1,720,969 research outputs found
A case of ‘anaphylactic-like’ reaction during LDL apheresis: a pathophysiological hypothesis on white wine containing metabisulphite
No full textCase presentation: This report regards a 60-year-old man affected by heterozygous familial hypercholesterolemia associated with high levels of lipoprotein (a), coronary and polidistrectual atherosclerotic disease. Patient has been treated with Atorvastatin 20 mg OD and LDL-apheresis (Heparin mediated LDL precipitation system every 2 weeks treating 4000 ml of plasma for session) for eight years.
Patient was regularly treated without any relevant problem, but unexpectedly, he presented two consecutive episodes of systemic malaise characterized by sweating, paresthesias of the lips and flush. In the second episode, these symptoms were followed by bradycardia and presyncopal episode. Both events occurred after more than 2 hours treatment, and were cured with fluid administration and bolus of 500 mg methylprednisolone i.v. Blood pressure, normal before the LDL apheresis start of, was low but responsive to administration of fluids. The symptoms, however, were so grave to require the discontinuation of LDL apheresis procedures.
At the revaluation of the possible causes of these unexpected episodes, occurred in absence of technical problems and without drug therapy modifications (aspirin 100 mg OD, atenolol 50 mg OD and ramipril 5 mg OD), we observed changes in the lifestyle: at dinner, the patient drank 2 or 3 glasses of white wine craft produced. The following apheresis was performed without drinking wine and we did not report any inconvenient. Furthermore, no problems occurred in the subsequent 9 apheresis performed so far with this setting
Upregulation of the immune system in primary hypercholesterolaemia: effect of atorvastatin therapy
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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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