23,806 research outputs found
Three-Dimensional System-in-Package Using Stacked Silicon Platform Technology
No full textIn this paper, a novel method of fabricating three– dimensional (3-D) system-in-package (SiP) using a silicon carrier that can integrate known good dice with an integrated cooling solution is presented. The backbone of this stacked module is the fabrication of a silicon carrier with through-hole conductive interconnects. The design, process, and assembly to fabricate silicon through-hole interconnect using a wet silicon etching method is discussed in this paper. The process optimization to fabricate silicon carriers with solder through-hole interconnect within the design tolerance has been achieved. The design and modeling methodology to optimize the package in terms of electrical aspects of the stacked module is carried out to achieve less interconnect parasitics. An integrated cooling solution for 3-D stacked modules using single-phase and two-phase cooling solutions is also demonstrated for high-power applications. Known good thin flip-chip devices with daisy chain are fabricated and attached to the silicon carrier by flip-chip processes making it a known good carrier after electrical testing. Individual known good carriers are vertically integrated to form 3-D Si
Biotrickling Filtration for the Reduction of N<sub>2</sub>O Emitted during Wastewater Treatment: Results from a Long-Term In Situ Pilot-Scale Testing
No full textWastewater treatment plants (WWTPs) are a major source of N2O, a potent greenhouse gas with 300 times higher global warming potential than CO2. Several approaches have been proposed for mitigation of N2O emissions from WWTPs and have shown promising yet only site-specific results. Here, self-sustaining biotrickling filtration, an end-of-the-pipe treatment technology, was tested in situ at a full-scale WWTP under realistic operational conditions. Temporally varying untreated wastewater was used as trickling medium, and no temperature control was applied. The off-gas from the covered WWTP aerated section was conveyed through the pilot-scale reactor, and an average removal efficiency of 57.9 ± 29.1% was achieved during 165 days of operation despite the generally low and largely fluctuating influent N2O concentrations (ranging between 4.8 and 96.4 ppmv). For the following 60-day period, the continuously operated reactor system removed 43.0 ± 21.2% of the periodically augmented N2O, exhibiting elimination capacities as high as 5.25 g N2O m-3·h-1. Additionally, the bench-scale experiments performed abreast corroborated the resilience of the system to short-term N2O starvations. Our results corroborate the feasibility of biotrickling filtration for mitigating N2O emitted from WWTPs and demonstrate its robustness toward suboptimal field operating conditions and N2O starvation, as also supported by analyses of the microbial compositions and nosZ gene profiles.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Sanitary Engineerin
College of Engineering's Roe-Hoan Yoon named University Distinguished Professor
No full textThirty-one years after joining the Virginia Tech College of Engineering's mining and minerals engineering department, Roe-Hoan Yoon has been named a University Distinguished Professor by the Virginia Tech Board of Visitors.</p
Decentralized Approximate Bayesian Inference for Distributed Sensor Network
No full textBayesian models provide a framework for probabilistic modelling of complex datasets. Many such models are computationally demanding, especially in the presence of large datasets. In sensor network applications, statistical (Bayesian) parameter estimation usually relies on decentralized algorithms, in which both data and computation are distributed across the nodes of the network. In this paper we propose a framework for decentralized Bayesian learning using Bregman Alternating Direction Method of Multipliers (B-ADMM).We demonstrate the utility of our framework, with Mean Field Variational Bayes (MFVB) as the primitive for distributed affine structure from motion (SfM).Peer reviewe
Fast ADMM Algorithm for Distributed Optimization with Adaptive Penalty
No full textWe propose new methods to speed up convergence of the Alternating Direction Method of Multipliers (ADMM), a common optimization tool in the context of large scale and distributed learning. The proposed method accelerates the speed of convergence by automatically deciding the constraint penalty needed for parameter consensus in each iteration. In addition, we also propose an extension of the method that adaptively determines the maximum number of iterations to update the penalty. We show that this approach effectively leads to an adaptive, dynamic network topology underlying the distributed optimization. The utility of the new penalty update schemes is demonstrated on both synthetic and real data, including an instance of the probabilistic matrix factorization task known as the structure-from-motion problem.Peer reviewe
Jennifer C. POST, Sunmin YOON, and Charlotte D’EVELYN eds : Mongolian Sound Worlds
No full textLe présent ouvrage collectif, coordonné par les ethnomusicologues étatsuniennes Jennifer C. Post, Sunmin Yoon et Charlotte D’Evelyn, est justifié par un constat : les Mongols ont toujours vécu « dans un dialogue constant avec la musique et le son » (Yoon : 1). Le propos du livre est donc d’« embrasser la situation complexe des cultures sonores mongoles à l’orée du XXIe siècle [et] de partager des informations sur un large éventail de genres et de paysages sonores [eng. soundscapes] de la cult..
Early changes in 25-hydroxyvitamin D levelsand bone markers after monthly risedronatewith cholecalciferol in Korean patients with osteoporosis
No full textHo Yeon Chung,1 Jawon Koo,1 Su Kyoung Kwon,2 Moo-IL Kang,3 Seong-Hwan Moon,4 Jin-Young Park,5 Chan Soo Shin,6 Byung-Koo Yoon,7 Hyun-Koo Yoon,8 Jae-Suk Chang,9 Yoon-Sok Chung,10 Hyoung-Moo Park111Department of Internal Medicine, Kyung Hee University, 2Department of Statistics, 3Department of Internal Medicine, Catholic University of Korea, 4Department of Orthopedics, Yonsei University, 5Department of Orthopedics, Konkuk University, 6Department of Internal Medicine, Seoul National University, 7Department of Obstetrics and Gynecology, Sungkyunkwan University, 8Department of Internal Medicine, Kwandong University, 9Department of Orthopedics, University of Ulsan, Seoul, South Korea; 10Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea; 11Department of Obstetrics and Gynecology, Chung-Ang University, Seoul, South KoreaPurpose: This study investigated the efficacy and safety of monthly risedronate, with and without cholecalciferol, on 25-hydroxyvitamin D (25[OH]D) levels and bone markers in Korean patients with osteoporosis.Methods: A randomized, double-blinded, prospective, 16-week clinical trial was conducted in ten hospitals. A total of 150 subjects with osteoporosis were randomized to one of the two treatment groups: RSDM+ (monthly risedronate 150 mg and cholecalciferol 30,000 IU combined in a single pill, n = 74) or RSDM (monthly risedronate 150 mg alone, n = 76). We measured serum levels of 25-hydroxyvitamin D (25[OH]D), parathyroid hormone (PTH), and bone markers, as well as performing muscle-function tests at baseline and after 16 weeks of treatment.Results: After 16 weeks, serum 25(OH)D levels significantly increased from 17.8 to 26.8 ng/mL in the RSDM+ group, but did not change in the RSDM group. The RSDM+ group exhibited significantly decreased serum PTH from 46 to 36.7 pg/mL, while the RSDM group showed a tendency for PTH to increase from 38 to 40.6 pg/mL. In both groups, serum bone-specific alkaline phosphatase and C-terminal telopeptide rapidly declined, with significance at 16 weeks; there were no significant differences between the groups.Conclusion: A once-monthly pill of risedronate and cholecalciferol provided equivalent antiresorptive efficacy to risedronate alone in terms of bone turnover and improved 25(OH)D levels over the 16-week treatment period without significant adverse events in Korean patients with osteoporosis. Keywords: bisphosphonate, cholecalciferol, bone markers, 25(OH)
Kim Yoon Hwan
No full text학위논문(석사)--아주대학교 일반대학원 :응용생명공학과정,2010. 2감사의 글
Abstract
List of Figure
List of Table
Ⅰ. Introduction
Ⅱ. Theoretical Approach
A. Dextran
B. Pectin
C. Hyaluronic acid
D. Chitosan
E. Example regarding prevention of protein adsorption
F. Electrospinning
G. BCA(Bicinchoninic acid) assay
Ⅲ. Material and methods
A. Material
B. Attachment of polysaccharide on film
C. Adsorption of protein on surface
D. Analysis
E. Preparation of PVA membrane
F. Measurement of concentration amounts and adsorption amounts
Ⅳ. Results and discussions
A. Fluorescence Intensity for BSA quantitative analysis
B. Data analysis using Isoelectric point
C. Data analysis using structure of hydrogel
D. Hystogram regarding protein adsorption distribution
E. Preparation of PVA membrane
F. Polysaccharide coating on membrane surface
G. Relation between the concentration of solution and layer thickness
H. Measurement of water flow rate
I. Measurement of concentration amount and adsorption amount
J. Preparation of polysaccharide layer introduced hydrophilic branch
1 Carboxyl-terminated PEG synthesis
2 Surface modification of complex polysaccharide layer
3. Estimation of adsorption ability for modified polysaccharide layer
Ⅴ. Conclusion
Reference
국문요약MasterThis study makes to reduce a protein adsorption to the surface and obtain a high-yield product while we carry out the separation and extraction of protein. Adsorption of Protein, the most representative material among biomolecules, occurs at surface of membrane and disturbs efficient separation and extraction. To prevent the adsorption of protein, surface of membrane was modified into hydrophilic surface. In order to obtain hydrophilic surface, we used hydrophilic polysaccharide such as Pectin, Dextran, Hyaluronic acid and chitosan which is known a effective biomolecule's adsorption preventer. In order to enhance transmittance, we make membrane having a porous structure by using electrospinning. The modified surface of membrane was observed by SEM(Scanning Electron Microscope) and AFM(Atomic Force Microscope) and concentration amounts and adsorption amounts of protein were measured by BCA(Bicinchoninic acid) assay. And ultrafiltration system was used to investigate water flow rate. And the hydrophilic group is introduced into polysaccharide layer. Through this study, the protein adsorption of surface coated by polysaccharide was affected by electrostatic property between protein and polysaccharide. And the higher hydrophilicity of surface coated by polysaccharide is, the lower adsorption ratio of protein is. Also the membrane introducing MPEG-COOH on chitosan layer have an excellent performance regarding prevention of protein adsorption. These results lead us to the conclusion that membrane of several types were prepared by introducing functional group
Shewanella marisflavi Yoon, Yeo, Kim & Oh, 2004, sp. nov.
No full textDescription of Shewanella marisflavi sp. nov. Shewanella marisflavi (ma.ris.fla 9vi. L. gen. neut. n. maris of the sea; L. masc. adj. flavus yellow; N.L. gen. n. marisflavi of the Yellow Sea). Cells are straight rods, 0·8–1·1×2·0–3·5 µm on MA. Nonspore-forming. Motile by means of a single polar flagellum. Colonies are smooth, glistening, circular, flat to slightly raised, light brown in colour and 2·0–4·0 mm in diameter after 3 days incubation at 30 °C on MA. Growth occurs at 4 and 42 °C, but not above 43 °C. Growth is observed at pH 5·0, but not at pH 4·5. Optimal growth occurs in the presence of 2–3 % NaCl. No growth occurs in the presence of more than 9 % NaCl. Growth occurs under anaerobic conditions on MA. Casein, tyrosine and Tween 80 are hydrolysed. Aesculin, hypoxanthine, urea, xanthine and xylan (birch wool) are not hydrolysed. When assayed with the API ZYM system, alkaline phosphatase, esterase (C 4), esterase lipase (C 8), α-chymotrypsin, acid phosphatase, naphthol-AS-BI-phosphohydrolase and N -acetyl-βglucosaminidase are present and leucine arylamidase is weakly present, but lipase (C 14), valine arylamidase, cystine arylamidase, trypsin, α-galactosidase, β-galactosidase, βglucuronidase, α-glucosidase, β-glucosidase, α-mannosidase and α-fucosidase are absent. Acid is produced from D-cellobiose, D-glucose, maltose and D-ribose. Acid is not produced from L-arabinose, D-fructose, D-galactose, lactose, D-mannose, D-melezitose, melibiose, D-raffinose, L-rhamnose, stachyose, sucrose, D-trehalose, D-xylose, adonitol, D-mannitol, myo -inositol or D-sorbitol. Both menaquinones and ubiquinones are present; the predominant menaquinone is MK-7 and the predominant ubiquinones are Q-7 and Q-8. The major fatty acid is iso-C15: 0. The DNA G+C content is 51 mol% (determined by HPLC). Other phenotypic characteristics are given in Table 1. The type strain (SW-117T = KCCM 41822T = JCM 12192T) was isolated from sea water of the Yellow Sea in Korea.Published as part of Jung-Hoon Yoon, Soo-Hwan Yeo, In-Gi Kim & Tae-Kwang Oh, 2004, Shewanella marisflavi sp. nov. and Shewanella aquimarina sp. nov., slightly halophilic organisms isolated from sea water of the Yellow Sea in Korea, pp. 2347-2352 in International Journal of Systematic and Evolutionary Microbiology 54 on page 2351, DOI: 10.1099/ijs.0.63198-
A Knowledge Distribution Model to Support an Author in Narrative Creation
No full textAdjusting the knowledge of characters and the reader is a critical task for an author in narrative creation. Throughout a narrative, both characters and the reader experience events according to their own timelines and perspectives. They interpret information accumulated through their experience and update knowledge to the narrative-world which the author constructed. In this paper, we present a Knowledge Distribution Model which supports an author in finely controlling the knowledge of characters and the reader. Within the model, the Knowledge Structure is constructed by connecting event, information, and knowledge. The Knowledge State is evaluated as the degree of belief under the knowledge structure. We adopted a probabilistic reasoning model to calculate the knowledge state. The change in knowledge state, defined as Knowledge Flow, is visually presented to the author. We designed a GUI prototype to implement the proposed modeling process, and demonstrated the knowledge flow with an actual cinematic narrative
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