1,568 research outputs found

    Measurement of the CKM matrix element |Vcb | from B0 →d∗-l+νl at Belle

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    We present a new measurement of the Cabibbo-Kobayashi-Maskawa matrix element |Vcb| from B0→D∗-l+νl decays, reconstructed with the full Belle data set of 711 fb-1 integrated luminosity. Two form factor parametrizations, originally conceived by the Caprini-Lellouch-Neubert (CLN) and the Boyd, Grinstein and Lebed (BGL) groups, are used to extract the product F(1)ηEW|Vcb| and the decay form factors, where F(1) is the normalization factor and ηEW is a small electroweak correction. In the CLN parametrization we find F(1)ηEW|Vcb|=(35.06±0.15±0.56)×10-3, ρ2=1.106±0.031±0.007, R1(1)=1.229±0.028±0.009, R2(1)=0.852±0.021±0.006. For the BGL parametrization we obtain F(1)ηEW|Vcb|=(34.93±0.23±0.59)×10-3, which is consistent with the world average when correcting for F(1)ηEW. The branching fraction of B0→D∗-l+νl is measured to be B(B0→D∗-l+νl)=(4.90±0.02±0.16)%. We also present a new test of lepton flavor universality violation in semileptonic B decays, B(B0→D∗-e+ν)B(B0→D∗-μ+ν)=1.01±0.01±0.03. The errors quoted correspond to the statistical and systematic uncertainties, respectively. This is the most precise measurement of F(1)ηEW|Vcb| and form factors to date and the first experimental study of the BGL form factor parametrization in an experimental measurement

    Bone loss during gonadotropin-releasing-hormone agonist treatment in girls with true precocious puberty is not due to an impairment of calcitonin secretion

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    Gonadal steroids drive the significant bone mineral increase that occurs at puberty, while estrogen deprivation in postmenopausal women results in bone mass reduction. We looked for bone mineralization in girls with true precocious puberty (TPP) before and after six months of LH-RH analogs treatment. Calcitonin secretion in these girls were studied too. Bone mineral content (BMC) and BMC/BW ratio (single photon absorptiometry) were measured in seven girls (aged 4.3 to 8.7 years) with TPP before LH-RH agonist therapy (long acting D-Trp6-LH-RH 60-mu-g/kg im every 28 days) was started; the patients were reevaluated after six months of therapy. Before therapy, BMC and BMC/BW were increased for chronological age but appropriate for bone age according to our mineralization normative data. After six months of LH-RH analog administration, 17-beta-estradiol and LH levels were suppressed and BMC and BMC/BW showed a small but significant decrease (respectively - 5.4%, p < 0.02 and -6.3%, p < 0.02). Basal and calcium stimulated calcitonin levels (total and extractable) did not significantly change during the study period. We conclude that in girls with TPP bone mineralization was increased for chronological age but normal for bone age. The estrogen withdrawal secondary to LH-RH analog therapy caused a reduction in bone mass. Such a bone loss is not due to an impairment of calcitonin secretion

    Resilienza, tecnologia, ambiente costruito

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    L'articolo, nell’ambito delle attività di costituzione del cluster Progettazione ambientale della SITdA, presenta alcune riflessioni condotte sul tema della resilienza dal gruppo BETHA dell'Università degli Studi G. d'Annunzio di Chieti-Pescara e che possono delineare potenziali linee di sviluppo di interesse centrale per l’area della Progettazione tecnologica dell’architettura

    Cardiac autonomic modulation in normal, high-risk, and in vitro fertilization pregnancies during the first trimester

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    Objectives: The purpose of this study was to test the adaptation of autonomic modulation of heart rate in high-risk or in vitro fertilization (IVF) pregnancies during the first trimester. Study design: Thirty-three pregnant women were studied between 6.0 and 12.5 weeks of gestation and were divided into three groups: normal (n = 17), high-risk (n = 7), and IVF pregnancies (n = 9), together with 9 nonpregnant women of comparable age. All subjects underwent a short-term continuous electrocardiographic recording to measure short-term heart rate variability (HRV). Results: Average values of mean R-R interval, total power, and low-frequency (LF) component were similar in nonpregnant and normally pregnant women. The high-frequency (HF) component was only slightly increased in normal pregnant women but no difference was observed in LF/HF ratio. High-risk and IVF pregnancies were characterized by a significant increase in LF component in comparison to normal pregnancies. In pregnancies that had obstetric complications, signs of abnormal autonomic modulation of the sinus node were particularly evident. Conclusion: Short-term analysis of HRV in high-risk and IVF pregnancies was significantly different from that observed in normal pregnancies. These differences were more significant in those pregnancies later complicated by an adverse outcome, suggesting an early origin of these pathologic conditions
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