4,021 research outputs found

    Correction: Differences between experimental and placebo arms in manual therapy trials: a methodological review (BMC Medical Research Methodology, (2022), 22, 1, (219), 10.1186/s12874-022-01704-8)

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    Following publication of the original article [1], the authors reported an error in the presentation of author names. The given name and family name were swapped. The correct author names are as follows: Giandomenico D’Alessandro, Nuria Ruffini, Alessandro Aquino, Matteo Galli, Mattia Innocenti, Marco Tramontano, Francesco Cerritelli. The author group has been updated above and the original article [1] has been corrected

    boot_tide: residual bootstrap methods for parameter uncertainty assessment in tidal analysis with temporally correlated noise

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    Source code implementing the residual bootstrap algorithms presented in Innocenti, S. and Matte, P. and Fortin, V. and Bernier, N. B., (2022), Residual bootstrap methods for parameter uncertainty assessment in tidal analysis with temporally correlated noise, JTECH, DOI:10.1175/JTECH-D-21-0060.

    Our 10 Years’ Experience in Breast Asymmetry Correction

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    We read with great interest the article titled: ‘‘Our 10 Years’ experience in Breast asymmetry correction’’ by Patlazhan G. et al. The authors presented their personal experience with breast asymmetry correction, reporting a very large case series including different types of clinical findings. We completely agree with the authors that correction of asymmetry is a common problem in breast surgery, representing a difficult challenge for plastic surgeons, including preservation of the long-term results. Breast surgery includes a wide range of clinical aspects, and therefore, every single case should be carefully evaluated. We congratulate the authors for the significant number of presented cases and results, but we have some elements to discuss. According to the authors, simple augmentation mammoplasty with different implants in patients with native breast asymmetry could not be sufficient and breast glands should be remodelled to achieve a long-term satisfactory symmetry. The authors’ personal classification of asymmetry includes shape, volume, presence and severity of ptosis and nipple–areola complex aspects, but we believe that also the difference in consistency between the breasts, including gland and soft tissue coverage, should be considered and included as parameter in the classification of breast asymmetry. This parameter is a very sensitive finding, especially in some congenital breast malformations such as tuberous breasts because different consistencies strictly reflect in maintaining long-term symmetry [1–3]. Authors proposed the Volume Shift Test (VST) to assess breast asymmetry preoperatively as well as during the surgical procedure. While intraoperative VST is a real objective evaluation of asymmetry, preoperative VST is very subjective and affected by personal sensibility based on a great experience and therefore it could be useful for experienced surgeons. We cannot agree with the authors that in size 1-mammary glands-Grade 1-asymmetry patients, different implants alone could be sufficient to maintain long-term results. Forty ml in difference could be considered a very low difference in larger breasts, but it could represent a very sensitive issue producing an evident asymmetry over time for size 1 mammary glands-Grade 1-asymmetry patients, strongly reflecting in conserving long-term stability of surgical correction [1]. In fact, this relatively small amount of breast in this type of patient could be considerably modified during the woman’s life and therefore gland reduction of the bigger breast should be considered also in size 1-mammary glands-Grade 1-asymmetry patients. Moreover, breast reduction of size 1-mammary glands-Grade 1-asymmetry patients represents a non-invasive surgical step without particular morbidities [4, 5]

    Gynecomastia and Chest Masculinization: An Updated Comprehensive Reconstructive Algorithm

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    Background: Gynecomastia is a common finding in males. Clinical aspect varies widely in world populations showing peculiar hallmarks according to different body shapes reflecting personal expectations; therefore, a surgical plan must be tailored on individual basis to all type of patients. Materials and Method: A total of 522 patients, treated for bilateral gynecomastia from January 2007 to January 2019, were included and reviewed in this retrospective study. Considering physical status BMI, muscular trophism, hypertrophy of the mammary region, nipple–areola disorder, gland and skin cover consistency, a four-tier classification system has been used to classify the deformity and to assess a surgical plan. In all cases, a subcutaneous mastectomy was performed under direct vision. Results: No recurrence of the deformity was observed as well as major complications such as necrosis, and high level of satisfaction was observed in all groups. No breast cancer was found at the histological examinations Operative time ranged from 25 minutes up to 120 minutes and hospitalization time ranged from 1 to 3 days. Conclusion: Since the physical status is strictly related to the clinical features of the disorder, a comprehensive classification system and a reconstructive algorithm are proposed. Level of Evidence IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/0026

    The use of resected SMAS as autologous graft for the correction of nasolabial folds during rejuvenating procedures

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    Background and aim: Despite several techniques are proposed, treatment of nasolabial folds is often challenging. During rejuvenation procedures, the SMAS could be redraped or partially resected during the procedure. The aim of this study is to investigate the use of obtained SMAS strip as autologous graft, because of its solid but pliable consistence and fatty composition, to correct nasolabial folds during procedures with SMAS resection. Methods Between 2015 and 2018, 23 patients underwent SMAS graft for nasolabial fold correction. All procedures were performed under local anesthesia and no other cosmetic treatments, including HA fillers, have been done in the past 12 months. Results: 22 patients were declared eligible for the study. 20 patients were female, accounting for 90,91%. Mean age was 53 years old. Ancillary procedures were performed in 17 patients, including upper blepharoplasty (3, 13,63%), upper and lower blepharoplasty (5, 22,73%) and submental neck lift with platysma plication (15, 68,18%). Mean follow-up was 9 months. No major complications have been recorded: Only 1 case of minimal hematoma in the retroauricular region have been recorded and 1 patient required laser treatment for pathological scars. At follow-up, graft is completely integrated into the mid-fat compartment. As evinced from the FACE-Q analysis, the overall satisfaction rate is extremely high. These are very convincing data regarding the effectiveness of the technique and, despite a little bit longer downtime, is not invasive and led to natural long-lasting results event during motion. Conclusions: The use of SMAS graft during face-lift as nasolabial fold filler results in a satisfactory but natural filling of the folds, reducing the need for lateral tension and therefore assuring more natural results. Since its nature, SMAS, reduced in width to properly fit into the nasolabial fold, can be considered as an optimal autologous graft for replenish loss volumes of the face with aging. (www.actabiomedica.it)

    The diameter of cortical axons depends both on the area of origin and target

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    In primates, different cortical areas send axons of different diameters into comparable tracts, notably the corpus callosum (Tomasi S, Caminiti R, Innocenti GM. 2012. Areal differences in diameter and length of corticofugal projections. Cereb Cortex. 22:1463-1472). We now explored if an area also sends axons of different diameters to different targets. We find that the parietal area PEc sends thicker axons to area 4 and 6, and thinner ones to the cingulate region (area 24). Areas 4 and 9, each sends axons of different diameters to the nucleus caudatus, to different levels of the internal capsule, and to the thalamus. The internal capsule receives the thickest axon, followed by thalamus and nucleus caudatus. The 2 areas (4 and 9) differ in the diameter and length of axons to corresponding targets. We calculated how diameter determines conduction velocity of the axons and together with pathway length determines transmission delays between different brain sites. We propose that projections from and within the cerebral cortex consist of a complex system of lines of communication with different geometrical and time computing properties. © The Author 2013

    Stability Considerations in Quaternion Attitude Control using Discontinuous Lyapunov Functions

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    Unit quaternions are a powerful tool for singularity free analysis and the control of arbitrary amplitude motion in a three-dimensional space. The authors present the use of proportional derivative quaternion feedback stabilisation for relative motion attitude control. Global asymptotic stability is guaranteed by defining a particular Lyapunov function and formal requirements are established. Conditions for a finite time control are also presented
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