128 research outputs found
Novel local/nonlocal formulation of the stress-driven model through closed form solution for higher vibrations modes
No full textIn the present work, an innovative two-phases local/nonlocal constitutive mixture model based on the stress-driven model for free vibrations problems is presented. The above two-phases model has been formulated by defining a convex combination of local/nonlocal phases through a mixture parameter and the closed form solution for free vibrations problems is given. The proposed local/nonlocal model has been applied to compute the natural frequencies of four nanobeams study cases. The results are presented in terms of normalised natural frequency as function of both nonlocal and mixture parameters. First, the influence of the two parameters is studied. The effectiveness of the present model is discussed by comparing the results with those obtained by applying the Gradient Elasticity theory. Finally, the normalised natural frequencies for the second, third and fourth modes of vibrations are presented and discussed for each study case
Approaches for mapping susceptibility to rockfalls initiation in carbonate rock-masses: a case study from the Sorrento coast (southern Italy)
No full textMost of the shoreline of the Campania region, Southern Italy, is characterized by steep and high rocky slopes, then several localities, densely populated and highly touristic attractive for the worldwide famous landscapes are exposed to an high rockfall risk. Particularly, the touristic localities on the Sorrentine Peninsula, such as Sorrento,
Vico Equense and Amalfi, can be considered among the most representative case-studies prone to the recurrent instability of rock blocks. Due to the frequent location of settlements and roads underneath and at very limited or null distances from the carbonate steep slopes, a diffuse condition of high rockfall risk exists. Consequently, the assessment of priorities in directing active remedial works to be carried out on the unstable rock slopes is still a challenging issue.
In order to find an effective method for assessing the susceptibility to rockfall initiation with approaches suitable for detailed mapping, a combined application of standard methods was tested.
The Romana’s Slope Mass Rating (SMR) and the Matheson’s graphical tests, for assessing the number of fundamental instability mechanisms, were applied in a test site of the Sorrento coast. Results of the two methods were separately evaluated and then combined in a new
rating approach by indexing the respective susceptibility classes. In addition, the number of joint sets and the macro-structural features of the rock-mass (faults and master joints) were considered. By means of statistical analyses of rockfalls occurred in the test area, the results obtained with the new combined approach were found
more accurate in assessing and mapping the most susceptible areas
Approaches for mapping susceptibility to slope instability in carbonate rock-masses: case studies from the Sorrento-Amalfi coast (southern Italy)
No full textAn observational retrospective/horizontal study to compare oxygen-ozone therapy and/or global postural re-education in complicated chronic low back pain.
No full text
Two cases of 16q12.1q21 deletions and refinement of the critical region
No full textInterstitial deletions of 16q chromosome including 16q12.1q21 region are very rare, with only three cases reported to date. Main clinical features include dysmorphisms, short stature, microcephaly, eye abnormalities, epilepsy, development delay, intellectual disability, and autism spectrum disorder. We report two independent subjects with 16q12.1q21 deletion syndrome presenting with dysmorphic facial features, developmental delay, strabismus, and aggressive behavior. A minimal region of overlap spanning 1.7 Mb on chromosome 16, including IRX5, GNAO1, and NUDT21 genes was shared among these two cases and those previously reported. This minimal region of overlap suggests the potential pathogenic role of these genes, previously implicated in diseases of the central nervous system
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