1,721,005 research outputs found
Composizione polifenolica del vino rosso “Castel del Monte” nel corso dell’invecchiamento
No full textInfluenza esercitata dall’aumento della produzione viticola sulla composizione antocianica del vino e considerazioni tecnologiche
No full textSulla validità dell’impiego degli enzimi pectolitici nelle vinificazione con macerazione
No full textL’influenza di alcuni trattamenti tecnologici sulla suscettibilità alla maderizzazione del vino bianco
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Ottimizzazione del Progetto di un Accoppiatore Direzionale Verticale con Cristalli Liquidi Ferroelettrici a Superfici Stabilizzate
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Anticancer Effects of Grape Seed Extract on Human Cancers: A Review
No full textGrape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols
and phenolic acids. Their consumption is safe and is recognized to exert several and meaningful health benefits.
In particular, grape-related anti-tumoral activity encompasses a wide array of biological mechanisms and cellular
targets, eventually leading to inhibition of cell growth and to enhanced apoptosis in several cancer cell lines, including
lung, colon, breast, bladder, leukemia and prostate tumors. Those effects are likely modulated at the molecular
level through selectively modulating the redox balance and displaying anti-oxidant as well as pro-oxidant actions,
according to the specific context. GSE-related anti-cancer activity mostly relies on the induced increase in reactive
oxygen species, followed by the orchestrated down- and up-regulation of several key-molecular pathways, including
MAPK kinases, PI3K/Akt, NF-kB, cytoskeleton proteins and metalloproteinases. Promising results obtained in vitro as
well as on animal studies suggest that GSE may have a great relevance as source of potential new pharmacological
molecules, and could represent an important opportunity for clinical research
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