840 research outputs found
Innovation performance in traditional industries: Does proximity to universities matter
No full textFirms operating in traditional industries are characterized by low investment in R&D and little capabilities for autonomous innovation. This situation is changing given the increasing relevance of general purpose technol-ogies, such as ICT. As a result, the innovative performance of firms in these sectors should be more dependent on the interaction with firms and institutions outside their production chain. The aim of this paper is to analyze to what extent the proximity to universities affects firms' capability to innovate as opposed to the other charac-teristics of the local context, such as specialization or variety, which motivated firms' location choice. The analysis focuses on Italian firms in traditional industries: agri-food, textile and clothing, leather and footwear. The empirical evidence suggests that the local context still plays a relevant role for the innovative performance of traditional firms while proximity to a university is not always statistically significant
Changing models of innovation in the eu textile and clothing industry
No full textFirms in the textile and clothing industry are generally considered as «suppliers dominated» for their innovation model, being characterized by low investment in r&d and little capabilities for autonomous innovation. As a result, technological innovation is not considered a key competitive factor. This situation is supposed to rapidly changing as a result of the increasing relevance of the so-called transversal technologies, such as ict, and the diffusion of open innovation models. The main aim of this paper is to analyze the characteristics and changes in the innovation model of eu firms in the textile and clothing industry over the last two decades. Empirical results reveal that in general firms remain characterized by a low intensity of innovation and patenting activity. However, the patenting and co-patenting activity of firms and the technological span of patents have significantly increased during the last decade, suggesting significant changes in their innovation model. Moreover, the innovation activity is highly concentrated in specific areas within the eu
Development of viscous fingering between enclaves and host magma: evidence from Vegetation Island (Terra Nova Intrusive Complex, Antarctica)
No full textA wide range of types of contact morphology among mafic and felsic magmas are observed in outcrops on Vegetation Island (Terra Nova Intrusive Complex, Antarctica). Image analysis and fractal geometry techniques were applied for in-depth study of the mafic/felsic interface, with the aim of studying the origin of the varied morphologies. In particular, the length (IPN) and fractal dimension (D-box) of interfaces were measured. Results indicate that there is a close exponential dependence of IPN on D-box.
The observed morphologies are identical to those observed during viscous fingering processes induced by the displacement of a more viscous fluid by a less viscous one. To test if viscous fingering was responsible in this case too, IPN and D-box values were measured on viscous fingering structures obtained experimentally using various viscosity ratios (V-R) from the literature. Results indicate that, as in the natural case, there is an exponential dependence of IPN on D-box, leading to the conclusion that the varied interface morphologies between mafic and felsic magmas are the result of viscous fingering dynamics. In addition, experimental studies clearly show that there is an exponential relationship between the viscosity ratio of fluids and the interface fractal dimension (D-box), and the ratio between the two types of magma was estimated using this relationship. It is shown that viscosity contrasts between mafic and felsic magmas varied considerably, ratios ranging from ca. 6 to 49. These results, together with outcrop evidence, provide indications regarding the evolution of the magmatic system, which generated the actual mafic/felsic associations on Vegetation Island
Entrepreneurial ecosystems and economic resilience at local level
No full textThe main aim of this paper is to investigate if and to what extent entrepreneurial ecosystems (EE) have an impact on economic resilience at local level. The paper is based on a quantitative analysis for the Italian provinces (NUT-3 level) and presents two novelties: first, it provides a composite index of EE at local level by capturing the different aspects encompassing political, social, cultural and economic dimensions of an EE; second, it analyzes the role of EE in terms of resistance to and recovery from external shocks. The empirical results show that EE has a relevant role in explaining the resilience of local systems to economic shocks. The positive effect also remains when controlling for the direct impact of new firm formation, thus highlighting that the EE concept has a greater significance for characterizing resilience and entrepreneurial activity at local level than entrepreneurial rates
Entrepreneurial ecosystems in Italy
No full textThe main aim of this paper is to develop a measure of entrepreneurial ecosystems (ee) at local level. We select and aggregate into a composite index 13 variables that represent the different features of an ee. Data refers to Italian provinces (nuts-3 level) in the years 2004 and 2011. The ee index shows a large variation between Italian provinces but a high persistence over time. We analyse the consistency of the index to different weighting procedure, normalization and aggregation methods. We also check for the sensitivity of the index in ranking the provinces to the removal of each variable
Monografia: Karl Mannheim
No full textSi tratta della sezione monografica della rivista Studi Perugini dedicata al pensiero di Karl Mannheim e curata da A. Santambrogio, con contributi di H. E. S. Woldring, D. Kettler e V. Meja, K. H. Wolff, A. Santambrogio, R. Kilminster, A. Izzo, L. Bailey, B. Longhurst, D. Pels, G. Perrotti, G. Morra, F. Ferrarotti, C. C. Canta, L. Allodi, E. Gabor
Smart Specialisation Strategy in practice: have regions changed the allocation of Structural Funds?
No full textThis paper evaluates to what extent the implementation of Smart Specialisation Strategy (S3) has changed the allocation of Structural Funds of Italian regions in the programming period 2014–20. Given the novelties introduced by this policy, we expect an increase in the sectoral and technological concentration of funds, a higher share assigned to research and technological development, and a stronger involvement of universities and research centres in the projects funded by regional authorities. In the empirical analysis, we exploit OpenCoesione, an original database that tracks all the projects funded with European Union Cohesion Funds in Italy. We compare the characteristics of the projects managed by regional authorities in two consecutive programming periods, namely, the one following and the one preceding S3 policy and implementation. The results show that changes between the two programming periods are modest and heterogeneous between regions. Overall, there is no strong evidence of any substantial change in how regions have allocated Structural Funds
Traigo conmigo todo el mapa de España. Le peregrinazioni di Teresa (León)
No full textSia nella sua opera più famosa, Memoria de la melancolia, come nelle sue raccolte di racconti, María Teresa León trova la sua cifra più personale e affascinante nella struttura rapsodica, con connessioni interiori e relazioni e oltre la logica e la cronologia degli eventi. L’autrice sembra leggere il tempo nello spazio attraverso una sorta di scrittura benjaminiana, costruita con citazioni ed episodi narrati in un necessario disordine di analessi e prolessi, rivivendo i tanti luoghi della la sua esistenza avventurosa, dall’Europa dilaniata dalla guerra all’America.Traigo conmigo todo el mapa de España. Teresa (León)’s travelsWell-evident in her most famous work, Memoria de la melancholia, as well as in her short story collections María Teresa León’s cypher shows a rhapsodic structure, based on internal connection and beyond the logic and chronology of events. The author seems to read time in space through a sort of Benjaminian writing, structured on quotations and episodes, ordered through analepsis and prolepsis
Method for the intracellular regeneration of hyaluronic acid and cosmetic composition therefor
No full textThe present invention relates to a cosmetic method for the regeneration of hyaluronic acid in cells of connective
tissues, starting from the hyaluronic acid precursors D-glucuronic acid and N-acetyl-D-glucosamine, or derivatives thereof.
More specifically the invention provides a cosmetic composition containing liposomes loaded with D-glucuronic acid
and N-acetyl-D-glucosamine, or derivatives thereof, in admixture with a physiologically-acceptable carrier
Prognostic utility of the Perugini grading of 99m Tc-DPD scintigraphy in transthyretin (ATTR) amyloidosis and its relationship with skeletal muscle and soft tissue amyloid
No full textAims
High-grade (Perugini grade 2 or 3) cardiac uptake on bone scintigraphy with 99mTechnetium labelled 3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) has lately been confirmed to have high diagnostic sensitivity and specificity for cardiac transthyretin (ATTR) amyloidosis. We sought to determine whether patient stratification by Perugini grade on 99mTc-DPD scintigraphy has prognostic significance in ATTR amyloidosis.
Methods and results
Patient survival from time of 99mTc-DPD scintigraphy was determined in 602 patients with ATTR amyloidosis, including 377 with wild-type ATTR (ATTRwt) and 225 with mutant ATTR (ATTRm) amyloidosis. Patients were stratified according to Perugini grade (0-3) on 99mTc-DPD scan. The prognostic significance of additional patient and disease-related factors at baseline were determined. In the whole cohort, the finding of a Perugini grade 0 99mTc-DPD scan (n = 28) was invariably associated with absence of cardiac amyloid according to consensus criteria as well as significantly better patient survival compared to a Perugini grade 1 (n = 28), 2 (n = 436) or 3 (n = 110) 99mTc-DPD scan (P < 0.005). There were no differences in survival between patients with a grade 1, grade 2 or grade 3 99mTc-DPD scan in ATTRwt (n = 369), V122I-associated ATTRm (n = 92) or T60A–associated ATTRm (n = 59) amyloidosis. Cardiac amyloid burden, determined by equilibrium contrast cardiac magnetic resonance imaging, was similar between patients with Perugini grade 2 and Perugini grade 3 99mTc-DPD scans but skeletal muscle/soft tissue to femur ratio was substantially higher in the latter group (P < 0.001).
Conclusion
99mTc-DPD scintigraphy is exquisitely sensitive for identification of cardiac ATTR amyloid, but stratification by Perugini grade of positivity at diagnosis has no prognostic significance
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