43,026 research outputs found

    Letter from J. L. Robinson to J. D. Cox, 1870

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    Regarding the claim of J. M. Roane for goods furnished to the Indians in California about the year 1858

    Lester J. Cappon and the publishing of modern documentary editions

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    Documentary editing is a well-developed field connected to the historical and archival professions. It was not always so well established, as a study of Lester J. Cappon's career suggests. Between his work at the Institute of Early American History and Culture starting in the 1950s and his final years as a fellow at the Newberry Library, Cappon played an important role in nurturing documentary editing as a profession

    Letter from J. L. Robinson to J. D. Cox with letter from J. M. Roane, 1870

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    Enclosed a letter from J. M. Roane explaning this business situation with the Indian service in California

    Illustration, Major General J. Dolson Cox

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    This black and white illustration is of Jacob D. Cox, a statesman, lawyer, Union Army general during the American Civil War, Republican politician from Ohio, Liberal Republican Party founder, educator, author, and recognized microbiologist. Cox is depicted wearing a dark, double-breasted military uniform with star-studded shoulder boards. The engraver\u27s name, J. C. Buttre, is listed along the bottom edge of the illustration. Cox\u27s signature is depicted below the illustration and his name is captioned beneath the signature. The original publisher, J. C. Buttre, is listed at the bottom of the page. The illustration is from volume nine of Abraham Lincoln : A History by John G. Nicolay and John Hay.https://scholarsjunction.msstate.edu/fvw-manuscripts-nicolay-and-hay-images/1507/thumbnail.jp

    Letter from J. D. Cox to Commissioner of Indian Affairs, 1869

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    Denied the claim of Thos. J. Henley for travel expenses to Washington D. C. to settle his account

    COX-2 immune-stained neurons in the brain sections of mice (magnifications: 10X, 40X).

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    The photomicrograph illustrates the following groups: (a, b) normal mice showing insignificant COX-2-immune positive cells, (c, d) control mice showing significant increase of COX-2 expression in the cerebral cortical neurons, (e, f) Ambrosin (5 mg/kg/day) treated mice showing reduction of COX-2 expression, (g, h) Ambrosin (10 mg/kg/day) treated mice showing COX-2 expression in fewer numbers of neurons, and (i, j) Curcumin treated mice showing individual COX-2 immune-stained cells. (COX-2 immunohistochemical stain).</p

    Selective COX-2 inhibitors and risk of myocardial infarction

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    Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids. Recently some coxibs, which were designed to exploit the advantageous effects of non- steroidal anti-inflammatory drugs while evading their side effects, have been reported to increase the risk of myocardial infarction and atherothrombotic events. This has led to the withdrawal of rofecoxib from global markets, and warnings have been issued by drug authorities about similar events during the use of celecoxib or valdecoxib/ parecoxib, bringing about questions of an inherent atherothrombotic risk of all coxibs and consequences that should be drawn by health care professionals. These questions need to be addressed in light of the known effects of selective inhibition of COX- 2 on the cardiovascular system. Although COX- 2, in contrast to the cyclooxygenase-1 ( COX- 1) isoform, is regarded as an inducible enzyme that only has a role in pathophysiological processes like pain and inflammation, experimental and clinical studies have shown that COX- 2 is constitutively expressed in tissues like the kidney or vascular endothelium, where it executes important physiological functions. COX- 2- dependent formation of prostanoids not only results in the mediation of pain or inflammatory signals but also in the maintenance of vascular integrity. Especially prostacyclin ( PGI(2)), which exerts vasodilatory and antiplatelet properties, is formed to a significant extent by COX- 2, and its levels are reduced to less than half of normal when COX- 2 is inhibited. This review outlines the rationale for the development of selective COX- 2 inhibitors and the pathophysiological consequences of selective inhibition of COX- 2 with special regard to vasoactive prostaglandins. It describes coxibs that are currently available, evaluates the current knowledge on the risk of atherothrombotic events associated with their intake and critically discusses the consequences that should be drawn from these insights. Copyright (C) 2005 S. Karger AG, Basel

    Torquay, Devon

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    'TORQUAY. DEVON. D. Cox. J. Rogers.

    Lester J. Cappon, scholarly publishing, and the atlas of early American history, 1957-1976

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    The Atlas of Early American History: The Revolutionary Era 1760-1790, published in 1976, remains one of the lasting legacies of the US Bicentennial. Funded by the National Endowment for the Humanities and a variety of private foundations, the publication was only incidentally a product of the celebration of the birth of a nation. The Atlas was the product of twenty years of effort by Lester J. Cappon-historian, archivist, and documentary editor-and because of his commitment to maintaining his own personal archives, we can learn more about this scholarly publishing venture than most. His rich diaries, personal papers, and Atlas archives enable us to follow the trials and tribulations of this publishing venture. We also learn that the kinds of issues facing scholarly publishing today, with a few differences (such as e-publishing), are not unique at all from those of half a century ago

    Laminicoccus asteliae Cox

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    Laminicoccus asteliae Cox Laminicoccus asteliae Cox, 1987: 50; Ben­Dov, 1994: 210. Holotype NEW ZEALAND, Auckland, Titirangi (NZAC). Comments Distinguishing characters of this species are the absence of a circulus and the presence of oral­collar tubular ducts on the venter around the vulva only. Oral­rim tubular ducts are absent completely and tubular ducts of any type are absent from the dorsum. Multilocular disc pores are represented by only one or two around the vulva or they are absent.Published as part of Williams, D. J. & Martin, J. H., 2005, (Hemiptera: Coccoidea: Pseudococcidae), pp. 1-12 in Zootaxa 804 on page 3, DOI: 10.5281/zenodo.17057
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