9 research outputs found
Serum cardiac troponin I values in patients after different kinds of coronary artery bypass surgery
Serum cardiac troponin I after conventional and minimal invasive coronary artery bypass surgery
Adipokines, hormonal parameters, and cardiovascular risk factors : similarities and differences between patients with erectile dysfunction of arteriogenic and nonarteriogenic origin
Introduction. Erectile dysfunction (ED) is often associated with metabolic disorders. Leptin and adiponectin are adipose tissue-derived hormones involved in the regulation of metabolic homeostasis and considered important players in the relationship among obesity and cardiovascular diseases. Aim. Leptin, adiponectin, leptin to adiponectin ratio (L/A), and their correlation with hormonal and metabolic parameters were examined in male with arteriogenic- (A-ED) and nonarteriogenic-ED (NA-ED). Main Outcome Measures. Biochemical, metabolic, and hormonal parameters of men with A-ED were compared with those of male with NA-ED. Methods. Diagnosis of ED was based on the International Index of Erectile Function Score. Its etiology was classified with penile echo-color Doppler at baseline and after intracavernous injection of prostaglandin E1. Leptin and adiponectin were measured by enzyme-linked immunosorbent assay. Results. In A-ED subjects, increased levels of insulin, glycated hemoglobin, homeostasis model assessment of insulin resistance (HOMA-IR) index, body mass index (BMI), leptin, and L/A and decreased levels of total, free, and bioavailable testosterone were observed compared with NA-ED subjects. A trend toward lower estradiol level was also present in A-ED patients, even if not statistically significant. Reduced levels of adiponectin have been observed in both groups compared with patients without ED. Leptin and L/A correlated similarly with several parameters (negatively with testosterone/estradiol ratio and positively with BMI, insulin, HOMA-IR, and 17-beta estradiol). L/A resulted further correlated negatively with high-density lipoprotein and positively with triglycerides. Conclusions. Not all ED cases are similar. In fact, A-ED patients display a more complicated metabolic status characterized by overweight and obesity and associated to sexual hormone alteration. Whether changes in body composition and modulation of adipokine levels can improve local endothelial function need further investigation. Dozio E, Barassi A, Dogliotti G, Malavazos AE, Colpi GM, D'Eril GVM, and Corsi MM. Adipokines, hormonal parameters, and cardiovascular risk factors: Similarities and differences between patients with erectile dysfunction of arteriogenic and nonarteriogenic origi
Nonlinear Measurement Update for Recursive Filtering Based on the Gauss von Mises Distribution
AbstractIn conventional Kalman-based state estimation algorithms, there is an assumption that the uncertainties in the system state and measurements are Gaussian distributed. However, this Gaussian assumption ignores the periodic nature of angular or orientation quantities. In this paper, the Gauss von Mises (GVM) distribution model defined on a cylindrical manifold is employed, the Dirac mixture approximation method is extended to deal with sampling with GVM, in order to perform recursive filtering, the GVM approximation to joint distribution is proposed, the formula to compute posterior distribution is derived. Finally, the measurement update algorithm is developed. Simulation results show that when the system state contains a circular variable, the proposed GVM filter can achieve more accurate estimates than the traditional extended Kalmanfilter(EKF), thereby providing a novel method to estimate system state specialized to GVM distribution
Mental health conditions and use of rhythm control therapies in patients with atrial fibrillation: a nationwide cohort study
Publisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.OBJECTIVES: Mental health conditions (MHCs) have been associated with undertreatment of unrelated medical conditions, but whether patients with MHCs face disparities in receiving rhythm control therapies for atrial fibrillation (AF) is currently unknown. We assessed the hypothesis that MHCs are associated with a lower use of antiarrhythmic therapies (AATs). DESIGN: A nationwide retrospective registry-based cohort study. SETTING: The Finnish AntiCoagulation in Atrial Fibrillation cohort included records on all patients with AF in Finland during 2007-2018 identified from nationwide registries covering all levels of care as well as drug purchases. MHCs of interest were diagnosed depression, bipolar disorder, anxiety disorder, schizophrenia and any MHC. PARTICIPANTS: We identified 239 222 patients (mean age 72.6±13.2 years; 49.8% women) with incident AF, in whom the prevalence of any MHC was 19.9%. OUTCOMES: Primary outcome was use of any AAT, including cardioversion, catheter ablation, and fulfilled antiarrhythmic drug (AAD) prescription. RESULTS: Lower overall use of any AAT emerged in patients with any MHC than in those without MHC (16.9% vs 22.9%, p<0.001). Any MHC, depression, bipolar disorder, anxiety disorder and schizophrenia were all associated with lower incidence of any AAT with adjusted subdistribution HRs of 0.790 (95% CI 0.771 to 0.809), 0.817 (0.796 to 0.838), 0.811 (0.789 to 0.835), 0.807 (0.785 to 0.830) and 0.795 (0.773 to 0.818), respectively. Adjusted rates of AAD, cardioversion and catheter ablation use were lower in all MHC groups compared with patients without MHC. The findings in patients with any MHC were confirmed in propensity score matching analysis. CONCLUSIONS: Among patients with AF, a clear disparity exists in AAT use between those with and without MHCs. TRIAL REGISTRATION NUMBER: ClinicalTrials Identifier: NCT04645537; ENCePP Identifier: EUPAS29845.Peer reviewe
Perioperative Bleeding Requiring Blood Transfusions is Associated With Increased Risk of Stroke After Transcatheter and Surgical Aortic Valve Replacement
Objectives: The authors aimed to investigate the impact of severe bleeding and use of red blood cell (RBC) transfusion on the development of postoperative stroke after surgical (SAVR) and transcatheter aortic valve replacement (TAVR), taken from the FinnValve registry. Design: Nationwide, retrospective observational study. Setting: Five Finnish university hospitals participated in the registry. Participants: A total of 6,463 patients who underwent SAVR (n = 4,333) or TAVR (n = 2,130). Interventions: Patients who underwent TAVR or SAVR with a bioprosthesis with or without coronary revascularization. Measurements and Main Results: The incidence of postoperative stroke after SAVR was 3.8%. In multivariate analysis, the number of trans-fused RBC units (odds ratio [OR], 1.098; 95% confidence interval [CI], 1.064-1.133) was one of the independent predictors of postoperative stroke. The incidence of stroke increased, along with the severity of perioperative bleeding, according to the European Coronary Artery Bypass Grafting (E-CABG) bleeding grades were as follows: grade 0, 2.2% (reference group); grade 1, 3.4% (adjusted OR, 1.841; 95% CI, 1.105-3.066); grade 2, 5.5% (adjusted OR, 3.282; 95% CI, 1.948-5.529); and grade 3, 14.8% (adjusted OR, 7.103; 95% CI, 3.612-13.966). The inci-dence of postoperative stroke after TAVR was 2.5%. The number of transfused RBC units was an independent predictor of stroke after TAVR (adjusted OR, 1.155; 95% CI, 1.058-1.261). The incidence of postoperative stroke increased, along with the severity of perioperative bleeding, as stratified by the E-CABG bleeding grades: E-CABG grade 0, 1.7%; grade 1, 5.3% (adjusted OR, 1.270; 95% CI, 0.532-3.035); grade 2, 10.0% (adjusted OR, 2.898; 95% CI, 1.101-7.627); and grade 3, 30.0% (adjusted OR, 10.706; 95% CI, 2.389-47.987). Conclusions: Perioperative bleeding requiring RBC transfusion and/or reoperation for intrathoracic bleeding is associated with an increased risk of postoperative stroke after SAVR and TAVR. Patient blood management and meticulous preprocedural planning and operative technique aiming to avoid significant perioperative bleeding may reduce the risk of cerebrovascular complications. (C) 2022 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Peer reviewe
0007
Young man I
Buy your
will be when you get a
home* and if you will
take the time to call at
my office, or write me
I will be glad to
explain a plan
whereby you
can get a home
|ust like paying
rent.
Cast your eye on the
following homes offered
for sale:
COTTAGE of 4 rooms and bath,
modern, sunny side of street,
size of lot 50x112; location four
blocks from Palo Alto Hotel
COTTAGE of 5 rooms and bath, size
of lot 40x115 with a barn; location one block from schoolhouse
This property can be purchased
at 500—Location Horner Avenue
50x200. This is a splendid
lot for the monoy.
$-00—Location Hawthorne Ave.
50,200. Tins is also a splendid bargain. *
A word to any um- desiring tu
purchase Pain Altu property. I believe thai all unimpruved property
ana' utTercd fur sale in Pain Aim
sbnuld be suld at least one-tbird
hiiihti. In nu place in California
can tbe same amount nf mnney lie
invested and equally, as good re-
- turns be obtained as in Palo Alto
real estate.
Call ur vita, tur raj .1.1 af bar.alas la
l,„|,,,,rr,l as w«ll as anirapritvril jirnpertjr.
J. J. Morris
Palo Alto. Cal.
AN OLD BOOK.
B. P. Hall bas Ln his possession a
volume that waa a popular addition to
the Sunday scbool libraries a half century ago. It was written by Amelia
Ople and is eoUUed "Lying In All IU
Branches." The author must have
been another, judging by tbe startling
occurrences related iu tbi* volume,
mauy of wbicb could not possibly bavo
happened except by special dispell
Mil imi uf providence. Tbe book must
bave afforded the children wbo read
it mauy new ideas iu tbe art of lylug
plausibly to tbeir puritanic jiareut*.
Yot sucb a book was suppoaeed to be
proper reading for young people. It
would not be allowed in a Sunday
scbool library at tbe present day aud
aurely no obild aould bo loducod to
read It now. Tho child of tbo proe-
ent day baa a better mental training
for hfc than did the children of
earlier generations, but perhaps thl*
advantage ia offset by tbo lack or
oourteey and good breediug that pro*
vails among twentieth century children.
Church News
Congregational Cburob—Tbe First
Congregational cburcb will bold Ita
Sunday school a; Fraternity Hall at
G: t... will null" with the Presbyterian
church at 11 a. m. and 6:45, and
with all the churches of the city at 8
p. m. In Mullen's Hall.
At tbe union service* of all tbe
churches to be held fSuuday evening
at 8 o'olook at Mullen'* Hall, Miss
Emily Blssell uf India will luij-eraon-
ate a blgb caste Indian woman and
will tell ber story iu costume". Miss
Hi- ''ll bos herself been a missionary
lu ludia : n.i'i- 1885 aud ber mother
haa boot, a missionary thereover flfty-
two years. The aervlce will be instructive uud lntereatlug to all.
Methodist Church— Hamilton are*
hue. aud Webster atreet. AIG:45 the
KpworLb League will have u -special
ttoug uud ri ni'-c service. Tbe music
will bo both lustrumental and vocal.
All are Invited to this service. Tbo
subject or tbe evening service is
"Wakllng witb Uod." Tbo Gloe Club
will slug at both or those services,
aud there will bo otber mualo. Mornlug worship at 11 a. m. Sunday
school at 0:46
Baptist Cburcb—Tbe pastor has
returned from the coast and will be
preseut at tbe aervlce* Sunday. In
tbe morning he will preach from tbe
same text u*ed by Mr. Wnitsker lost
Sunday evenlog, 2 Cor. 3:18. Tbe
church U to be congratulated on ae*
curing thoaerrlces ol Mr*. Dots Gibson, pupil or Llebliog or Chicago, for
tbe morning snd Professor Scott
Brook, the eminent organist of tbe
Memorial cburcb, 1* to play In tbe
evening. The morning numbers are:
Voluntary, AdagioSoatenuto, "Moonlight;" Sonata, Beethoven; offertory,
"To Spring," Orieg; Recessional,
Ve'raot, Lefebiiro-Wely. Tbe Sunday
achool meet* at 9:.5 a. m. and this
Suuday Bov. It. S. Tbompaou ol
Clovla, wIioho oomiug hH* oortainly
added much to tho working force of
j tho church, ha* kludly consented to
begin teaching tho adult Biblo class.
Tbe Voting Pooplo'a aoolety ia grow-
iug lu interest and attendance and
meeta at 7 :00 o'clock Suuday evening.
Uulon service In Mullon'a Hall lo tbe
evening.
TITLE QUIETED.
The trustees of tbe Congregational
cburcb purchased a lot near tbe corner of Hamilton avenue and Cowper
street a year or so ago and thia lot
was deeded to tbe late H. L. Brown
as trustee. Tbe lot was exchanged
for one opposite tbe Episcopal church,
but Mr. Brown'* death left no one
authorised to deed tbe lot to tbo new
owner. A friendly suit wus brought
by the trustees of tbo cburcb against
the heirs of Mr. Brown tu adjust tho
matter. On Weducsdity Judge BhodeH
ordered tho heirs to execute it deed
to tho fTuHit'i-.-. uud iu event of tholr
failure ao to do then the oounty clerk
In appointed commissioner to execute
auch deed. Norman E. Malcolm was
attorney for lbe plaintiffs and S. VV.
Cbarlea for tho defendants.
A POOR DIET.
Senator "Joe" Hitwley has a collection of dog stories, any ono of
which wins friends and votes.
He was taking a constitutional lu a
weateru New Vork village on a plena*
ant Hummer's day. While pas*ing
a cottage he wa* approached by Its
tenant, who looked like a panhaudlcr.
"Cau't you help me, sir?'* said tbe
man.
"Why, you cau't m---l anything,"
returned tbe Senator. "Vou have
four or five dog-i aiouud the place,
my man."
"That** true, sir," won the reply,
"but I can't compel my family lo eat
dog*."—Now Vork Time*.
BIDS ASKED.
Tbo regular date for the next meeting of the towo trustee* falls on July
4tb, a legal holiday, therefore tbe
meeting ba* been postponed to Thursday erenlng, July 0th. Bids will bo
received up to that time for tbe extension of tbe water system and for 500
feet uf Are hose. All wbo wish to
bid will Dud notice* in this issue, or
can gel any desired Information from
tbo towu clerk.
I). II. Wood met witb an accident
Wcdiicitduy night that laid him up
with a sprained ankle. He was riding Im!i.fi.ui'l-. uud in turning the corner at High uud University tbe horse
fell with .Mr. Wood underneath.
ProfoHnor Doiiglus Houghton Campbell of tho liotuuy department ut Stanfonl In olf on u trip to A nut ml in and
New Zealand. Flo will apoud the
Hummer vacation investigating plant
life in those countries.
E. K. I .--*- t-ll. wife and daughter will
go Into the l.i Honda couutry next
week, where they will enjoy camji life
foi a mouth or ao.
Mr*. Alfred Oriawold of Sau Francisco la vlaltlng her son, W. 11. Oris*
wold.
IN THE ARK.
It hub during tho llrnt bi-weekly
oakewalk In tbe iirk.
The other uuimtiltt hud done Iheir
best.
Then the Porcupine mid his wife
were teen coming down tho line doing
uu cMTuuiutliigly. funny atop.
"Isn't thut u pouch?" exclaimed
Father Ape, who was one of tho
Judges.
"1 thought it wurt a prickly pair?"
responded the Monkey, who limned!*
uli'ly round it advisable to seek the
j highest perch iu tbo vessel B«ltl*
I more American.
SUNDAY AT SEASHORE.
Low excursion rates to Sauta Cruz,
Monterey. Del Monte, Pacific Orovc,
C*plana. Try one day boating, bathing. Hulling, swimming, yachting.
Sec agent of Southern Pucillc.
RATES FOR THE FOURTH.
I The Southern Pacific Company announce* the usual low rates for Fourth
{of July travel. Tbo price* for round-
! trip tickets will be as follows: Ooe
j and ODe-thlrd fsre to points where tbe
rate I* 4,3.75 or less; 15 wben tbe
one way (arc hi 13.75 to 14.15; oue
and one-flfth fare wben tbe one-way
rate i* M. 15 to 90; 97.20 wben tbe
one-way fare is Id to 97.20; ono fore
wben tbe one-way rate Is 97.20 to
910. Tick.-i . will be sold on July 3d
and 4th, and will be good returning
until July 7th.
Profoesor .and* Mra. Eugene Smile
left tbla morning for (.leuwood, Santa
Cms oounty, for a month's vacation.
SPECIAL NOTICES.
LOST—A rnttorfiity pin. Finder
ploi.no return to postuiuuter and io-
celvo reward. 2f.lt*
0- II. ALLEN OIL CO. wish to nu-
iioiiuiio thut notwlthtiluiidlng the
existing shortage In gum-Hue thoy
are prepared to III! or.lent tor gitso-
llno Ht tho old price, 91.15 per 5
galloiis. 2U-tr
WANTED-Posltlou by u retlt.ed lady
to do light bouso work, plain cook,
take care of child, oi would take
charge of houne duriug owner's sb-
■euce. Befereuet**. Address Time*
office. 26tf
WANTED- Olri for general housework, uo cooking, wage* 915. Addreaa P. O. Box 7C, Menlo Park.
2G-lt
Miss Van Syckel has sold her. Interest In the novelty stoie to C. H.
William* roMutly of Fresno.
Meura.Whltmer k William* expect
toonlarge their present stock and
extend the business.
Chas, Whoatley representing tbe F.
Thomoo Dyeing and Cleaning Work*
' will make regular tripe to Palo Alto
commanding next Monday. Look
for announcement next week.
fill RENT— 358 Homer avenue, 5
roomed cottage.two roar rooma woll
rurnlabed. Three front rooma now
ien!.'.I for 910; wbolo cottago 925,
or 2 rear room. 912. Also 3 room
cottage In rear lot, partly furnished.
Rent 910-60. Uood plumbing. Free
water. Apply to S. E. von derMeb
den, 26 O'Parrel I. St., San Francisco. 3t*
WANTED—Household work by the
day by competent woman. Apply
st Mr. Barker's on Waverfy near
tbe creek. Mrs. Ueo. Hall. 4t*
FOft SALE— Seven room bouse at a
bargain, 418 Ramona street. tf
945—To Jet for tbe summer; completely furnished upper flat.of movou
rooms and bath. All modern convenience*, gas range lu kitchen,
telephone, piano, etc. Family
going to tho couutry ror thu summer. Addross J. Q. II., 1003 McAllister street, Ssu Frauotsoo.
FOR LOTS In tho Coleman Truck,
Menlo Park, seo J. T. Dunn, local
agent, 521 Emerson atroot.
THE EAGLE DRUG CO. ta head*
quarters [or Wakalou'a wull known
specialties—Camolllne, for the com-
nlt-xlon: Llkola, tbo tonic; Rosea and
Itosomar-/, for thc hair; Ma-suango
Hoadscbe Powders; Wak aloe's Foot
Powder; Cold Cream, Cucumber
Cream, Squirrel poison and many
other**.
FOR LOTS in tho Coleman Track at
Menlo Park, see J. T. Dunn, local
agent, 521 Emerson sir-.—t.
TO LET— During vacations very nloo
4-room cottage, fioely furnished, low
rent. J. T. DUNN,
521 Emerson Si.
TO RENT—From June let. A nine-
room furnished bouse ln Palo Alto.
All modern improvements and ample grounds. Address, P. O. Box
42, Stanford University. tt.
DRESSMAKING— .Miss liatcheller.
Room 16, Stauford Building.
TO RENT—House of flvo rooma, fur-
nlubod. Corner or Huwthoruu and
Kamona streets. Address < Im.
Nunu, Moulu Park,
LOST- -Gold rlna. In tho vicinity ot
Pulo Alto. FiiidurpleaBerett.ru to
Times ollico aud rucelvo reward. .IL
FOR SALE—A good second-hand
surrey cheap, lor cash or ln ox-
change ror a good family horse.
A. B. Show.
tf-25 353 Melville Avenue.
WANTED—To buy a fn**h milch cow,
Jersey breed only. Inquire of N.
S. Gulbersoo, last bouse on Emerson street, near creek. 25-2t
SALE—Of household furniture on
account of removal. Call at residence, 455 University Ave. 25-3t
PROFITALBE to BUVER and
SELLER—Steady employment for
an Bgent, lady or gentleman, to
supply the de.uaud lor au up-tu
date medical book, OH|KH-iully for
womeu uud children. How to keep
well, diet iu health aud i--'.- in
very helpful hi the cure of the sick.
Is explicit lu the truutmeuL of fevers. Cost about tho sumo u* one
or two visits of a physician or a
duy'u aorvico of u nurse. No married couple ahoold be without It,
with childreu it Is n crlmo to bo
without sucb a book. Circular
tmiiled free, address, "Publishers'
Ageut," 417 Purrott Bldg., San
Francisco, or care ol the Times
oflice, Palo Alto.
PROFESSIONAL NURSE—Will
go out by tbe day. Doctor's
lefcrerices. Address .Mrs. K.
Inez Faby- at Menlo Park, or
Tel. "Red 26. kwfwood Citv. tf.
IP VOU ARE INTERESTED in spring
Harness and Saddlery goode, or
Carriages see I. Stewart. Sewing
machine- lor sale on easy terms, or
to rent. tf.
WANTED—A reliable, Intelligent local man an agent fur Metropolitan
Life Ins. Co. Good op*>nrtiiDlty to
engage iu a permanent anti profitable iii-iii.-;. olferlug eteiuly it')-
viiucement. Call or i-ddrc-**, A.
M. Castle. Ass't Sup't. Rooms 4
k 5 Patrick Block, Pulo Alto. tf.
FOR SALE— 358 Homer avenuo.
Cottago of llvu large ninnm uud
iiutii,'i>i-iii imall cottage r :i roomi
with good ;.|i; in l.i in.- in rear lot.
Apply to S. E, Vou dor Mohtlou
26 0'FurrolISt.,Sau Frauclsco. 3t*
s--SV-"sV-sO.-*«y-*a--^^^. *S>-s»*r-sV-*^
j White Mountain Freezers
' At I.liSS Than City Prices
1 QUART tl.25
2 " 1.75
3 '• 210
4 " 2.60
0' " 3.15
8 QUART U.C0
10 " 6.25
12 " 7.00
15 " 10.00
We need not explain the merits of this Freezer,
It is too widely known for that, the freezer is all right
and so is the price.
THE REASON
we are selling them so cheap is because we have lots
of them and want to sell them.
J. F. Partinson
Six
O'CarxL
Store
The Haberdasher
Millinery
R.&G.
10RSII
2 TWO STORES 2
A COW
SI.ml
III Oil
LAWNS! LAWNS!
IOOO yards of choice
patterns in Lawns. Regular 8lc, 10c, i.jajc, and
ice per yard
Sale Price 5c yard
THE BEST, THE VERY BEST—THAT'S OUR MOTTQ
EARLE & CO.
GROCERS
All High Grade Groceries—They Speak for Themtelve,
COLUMBIA
tiocktmltbiog
Repairing
Renting
Sundries
TRIBUNE
Smith's
i Columbia!
\ Cyelery /
FRED M. SMITH.: .MO..
CLEVELAND
On the Circle
Palo Alto
F.ncin.-i Gvm
WOLF-AMERiriN
Just armed ! Fresh stock ol lowncy'a
IMiii.iM- Cbocolates-PAUCl PMAKU'CY.
Notice to Creditors.
Estate of lliaui* Tarbell. Deceased.
Notice la hereby given by tbe undersigned administratrix of tbe Estate of Blanca Tarbell. deceased, to
tbe creditors or and all pereona having claims against tbe aald deceased,
to exhibit tbe aame. with the uocea-
sary vouchors, within 4 months after
tbe Hi.-' publicatiou or tbis Notice, to
tbe said Administratrix at tbe oBlce
or Corbet k Ooodwln, No. 331 Pine
Street, City and County or San Francisco, sti.t... ot California.
Sao Jose, this 29 day of May, A. D.
1903.
OLUA 8. TARBELL,
As administratrix of tbe estate of
Blanca Tarbell. 'Jl.lt
siiffi
10 GRAND.
Tho Popular Soonlc Line to
Salt Lake City, Lcadville, Pueblo,Colorado Springs, Denver
Omaha, .Kansas Gty, St. Louis, Chicago and all Points East
Connecting ut Ogdon Union Dopol with all Southern Paclllc Trains
Only Truiui-e-mtiiH-ntal line passing directly tliroagll Suit Luke City
Personally conducted Tourist Excursions daily from California
to St. Louis, Chicago ami Botjlon
Choir.! of three separate routes through the Rocky Mountains
Through Pullman and Ordinary Sleeping Cars
To Denver, Omaha, Kansas City, Chicago and St. Louis Without cbangu
Fkke Reclisiso Ciiaik Cars
DIN1NG CARS—Sqrrlco a la Carto ON ALL tbrough trains
Por Rite*. Free II lu. listed Hook* of Trs.rl. etc , i = ', ulre of o. a nit lo
L. a. JOHNSON, Prt. ft Pa-*. Aft. J. D. M.inm'|i;i.'.i C«b. Agt. ps-i. D-pL "■
Jo-*. Cal. S15 Ms.Itet St.. etso ft. di-Imx). c*l
. 1 »>! -..-.t* i.:.i.
■i+l .*«>!-■--*>--.*>a-a>--jr^ !■} ^-a^H^^, ■) - y V |r ,,, ,, [■■SS-.K-H
Coal
Wood
F.L. WORRELL
?
PHONE RED 205
Hay
Grain
*'.a.otr.j|i:si*ii;>i.:i.i;>.o>;>i.>>:,..sr;^avi:iaai
A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomized controlled trial
Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services
