91,319 research outputs found
Leon Battista Alberti. Momo, Testo critico e Nota al testo di P. d'Alessandro e F. Furlan, Introduzione e Nota bibliografica di F. Furlan, Traduzione del testo latino, note e Postfazione di M. Martelli, volume a cura di F. Furlan
No full textDel “Momus” di Leon Battista Alberti, che l'autore non si decise mai a pubblicare, sono state pubblicate modernamente diverse edizioni, ma fino a oggi non si era mai riuscito a chiarire i rapporti semmatici interocorrenti tra i diversi testimoni del testo, tra cui due manoscritti idiografi e due edizioni a stampa contemporanee. Nell'edizione di Furlan e d'Alessandro, accompagnata da un'ampia e dettagliata “Nota al testo”, si ricostruiscono per la prima volta le diverse fasi di composizione, correzione e trasmissione dell'opera, stabilendo con certezza i rapporti tra i manoscritti e le edizioni a stampa e fornendo per la prima volta un testo conferme alla volontà ultima (se pure non definitiva) dell'Alberti
Leon Battista Alberti. Momo, Testo critico e Nota al testo di P. d'Alessandro e F. Furlan, Introduzione e Nota bibliografica di F. Furlan, Traduzione del testo latino, note e Postfazione di M. Martelli, volume a cura di F. Furlan
No full textDel “Momus” di Leon Battista Alberti, che l'autore non si decise mai a pubblicare, sono state pubblicate modernamente diverse edizioni, ma fino a oggi non si era mai riuscito a chiarire i rapporti semmatici interocorrenti tra i diversi testimoni del testo, tra cui due manoscritti idiografi e due edizioni a stampa contemporanee. Nell'edizione di Furlan e d'Alessandro, accompagnata da un'ampia e dettagliata “Nota al testo”, si ricostruiscono per la prima volta le diverse fasi di composizione, correzione e trasmissione dell'opera, stabilendo con certezza i rapporti tra i manoscritti e le edizioni a stampa e fornendo per la prima volta un testo conferme alla volontà ultima (se pure non definitiva) dell'Alberti
On the complexity of Simon automata over the Dyck language
No full textIn this paper the following problem is studied. Let be a finite alphabet where and are disjoint and equipotent sets. Let be a rational language over and let be the Simon distance automaton on L. Let be the square matrix with entries in the extended set of natural numbers given by the formula: for every pair of states of , is the minimum weight of a computation in from to labelled by a Dyck word if such a computation exists, otherwise it is . We exhibit a polynomial time algorithm which allows us to compute the matrix in the case in which is the unary alphabet. This result partially solves an open question raised in [F. d'Alessandro and J. Sakarovitch, Theoret. Comput. Sci. 293 (2003), no. 1, 55--82; MR1957613 (2003m:20025)]
Leonis Baptistae Alberti Momus, ediderunt Paolo d'Alessandro e Francesco Furlan, e Nota al texto, por Paolo d'Alessandro y Francesco Furlan, in Leon Battista Alberti. Momo (Biblioteca de la Utopiá, 16)
No full textRicostruzione stemmatica dei testimoni del Momus di Leon Battista Alberti (2 idiografi, alcuni apografi, due edizioni a stampa, di cui una instar codicis) ed edizione critica del test
A methodology to measure the acoustic performance of access floors
No full textThe European standard EN ISO 140-12:2000 gives a methodology to measure the acoustic performance of access floors in terms of both airborne and impact sound insulation.
Access floors are often used in office buildings and working environments as they create a hollow space below the floor surface for network cabling and electrical wiring: in this way they are useful from the functional (ease of inspection, repair and changing of system elements), the aesthetic (no exposed wires and elements) and acoustic point of view.
This paper presents the measurement procedures used at the Acoustic Laboratory of the University of Perugia – Italy, in order to perform the tests defined by the EN ISO 140-12.
The standard requires the measurement of two parameters, Ln,f e Dn,f , that qualify respectively the airborne and the impact sound insulation trough an access floor, and the calculation of the two corresponding single number indexes Ln,f,W e Dn,f,W.
A sample of access floor has been tested in the purposely prepared reverberating rooms of the Laboratory, with and without covering.
Particular attention has been paid to test rooms set up and to sample installation because of the complexity of these phases
Leonis Baptistae Alberti Momus, ediderunt Paolo d'Alessandro e Francesco Furlan, e Nota al texto, por Paolo d'Alessandro y Francesco Furlan, in Leon Battista Alberti. Momo (Biblioteca de la Utopiá, 16)
No full textRicostruzione stemmatica dei testimoni del Momus di Leon Battista Alberti (2 idiografi, alcuni apografi, due edizioni a stampa, di cui una instar codicis) ed edizione critica del test
Commento di F. D'Alessandro nel Codice delle confische, Parte II le confische nel codice penale e nella legislazione speciale
No full textLe confische nel codice penale e nella legislazione speciale: commento agli artt. 190 bis. 1 e 193 ter del Testo unico della finanza (d. lgs. 58/1998
La Treviri di Oswald Mathias Ungers
No full textTrier, characterized by the presence of numerous UNESCO World Heritage monuments, was considered by Oswald Mathias Ungers as his adoptive city. Here, the author had the opportunity to realise three build-ings that engage with the city’s historical heritage. The project for the redevelopment of Konstantinplatz, in front of the Basilica (1981-83), the Museum of the Thermen am Forum (1988-1996), and the entrance to the Kaiserthermen (2003-2007) are works that engage with the city’s historical legacy, making them exemplary witnesses of the relationship between architectural forms, history, and place. The paper proposes an interpre-tation of the works that not only aims to identify their characteristics and their relationship with history, but also and above all seeks to investigate the system of relationships that links Ungers to Trier. For this investi-gation, the author’s projects embody the value of a paradigm that outlines a possible contemporary attitude towards history in architectural design
Next generation sequencing for the molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy
No full textHypertrophic cardiomyopathy (HCM) is a common genetic heart disorder characterized by unexplained left ventricle hypertrophy associated with non-dilated ventricular chambers. Several genes encoding heart sarcomeric proteins have been associated to HCM, but a small proportion of HCM patients harbor alterations in other non-sarcomeric loci. The variable expression of HCM seems influenced by genetic modifier factors and new sequencing technologies are redefining the understanding of genotype-phenotype relationships, even if the interpretations of the numerous identified variants pose several challenges.We investigated 62 sarcomeric and non-sarcomeric genes in 41 HCM cases and in 3 HCM-related disorders patients. We found that 82% of the patients harbored at least one rare nsSNV: 11% of the patients showed only sarcomere nsSNVs, 20% of cases harbored at least one sarcomeric nsSNV with at least a desmosomal one and 14% displayed at least one desmosomal nsSNV but no other sarcomere change. We reported an association between desmosomal variations and the pathogenesis of HCM that has not been described to date. We employed an integrated approach that combines multiple tools for the prediction, annotation and visualization of functional variants. Several different methods were employed to predict the functional consequences of alleles that result in amino acid substitutions, to study the effect of some variants over the splicing process and to investigate the impact of these changes respect to the evolutionary conservation. Genotype-phenotype correlations were carried out for inspecting the involvement of each gene in age onset and clinical variability of HCM. Statistical analyses revealed an inverse correlation between the number of nsSNVs and age at onset, and a relationship between the clinical variability and number and type of variants. Then, we describe the clinical, pathological, and molecular features of the novel LAMP2 c.453delT mutation in one of our HCM-related disorders patients affected by Danon disease characterized by severe hypertrophic cardiomyopathy, mild intellectual impairment and rapid progression to heart failure, requiring heart transplant. Immunohistochemical analysis of LAMP2 in the explanted heart revealed a mosaic pattern of distribution, with discrete clusters of either stained or unstained cardiac myocytes, the latter being more frequent in the septum. Interestingly, multiple foci of microscarring were found on histology in the Left Ventricle (LV) free wall and septum. Our findings suggest that several features may contribute to the early and severe cardiac phenotype in female patients affected by Danon disease. In conclusion, this work aims to extend the mutational spectrum of HCM and to contribute in defining the molecular pathogenesis and inheritance pattern(s) of this condition. Besides, we delineate a specific procedure for the identification of the most likely pathogenetic variants for a next generation sequencing approach embodied in a clinical contex
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