1,762 research outputs found

    Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis

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    Recurrent bacterial meningitis is a rare phenomenon and generally poses a considerable diagnostic challenge to the clinician. Ultimately, a structured approach and early diagnosis of any underlying pathology are crucial to prevent further episodes and improve the overall outcome for the affected individual. In this article, we are reviewing the existing literature on this topic over the last two decades, encompassing 363 cases of recurrent bacterial meningitis described in 144 publications. Of these cases, 214 (59%) were related to anatomical problems, 132 (36%) were related to immunodeficiencies, and 17 (5%) were related to parameningeal infections. The review includes a detailed discussion of the underlying pathologies and microbiological aspects as well as recommendations for appropriate diagnostic pathways for investigating this unusual entity

    Enterovirus infections in neonates

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    Enteroviruses, which include echoviruses, coxsackie A and B viruses, polioviruses and the ‘numbered’ enteroviruses, are among the most common viruses causing disease in humans. A large proportion of enteroviral infections occur in neonates and infants. There is a wide spectrum of clinical manifestations that can be caused by enterovirusinfection with varying degrees of severity. In the neonatal age group, enteroviral infections are associated with significant morbidity and mortality, particularly when infection occurs antenatally. This review provides a detailed overview of the epidemiology and clinical features of enterovirusinfections in the neonatal period. In addition, laboratory features and diagnostic investigations are discussed. A review of the currently available data for prophylactic and therapeutic interventions, including antiviral therapy, is also presente

    Adenovirus infection in the immunocompromised host

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    There are 51 known serotypes of human adenovirus, which are divided into subgroups (or species) A to F Table ). An additional serotype (52), which potentially constitutes a new species (G), has recently been reported after genomic sequencing and phylogenetic analysis of an isolate in the U.S

    Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation

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    The desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters

    Ep. #181 - Nigel Clark

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    This recording and transcript form part of a collection of podcasts conducted by the Cultures of Energy at Rice University. Cultures of Energy brings writers, artists and scholars together to talk, think and feel their way into the Anthropocene. We cover serious issues like climate change, species extinction and energy transition. But we also try to confront seemingly huge and insurmountable problems with insight, creativity and laughter.Cymene and Dominic discuss a strange effort to police sugar packet play on this week’s podcast. Then (15:52) we are delighted to welcome Nigel Clark to the conversation. Nigel is Chair of Social Sustainability and Human Geography at Lancaster University (https://www.lancaster.ac.uk/lec/about-us/people/nigel-clark ). He is the author of Inhuman Nature: Sociable Life on a Dynamic Planet (2011) and co-editor of Atlas: Geography, Architecture and Change in an Interdependent World (2012), Material Geographies (2008) and Extending Hospitality(2009).  We start things off by talking about a new book he is working on called The Anthropocene and Societythat he is working on with Bron Szerszynski and what it means to rethink humanity through planetary strata, flows, and multiplicity. We turn from there to Australian feminism, phosphates, Aotearoa New Zealand as a space of settler grassland experiments, wealth, and geocide. Then we touch on fire and its excess, our brittle life on an earth’s surface caught between solar and geothermal vitalities, metamorphosis, the early connection between gunpowder and combustion engines and European geotrauma. A special birthday week shout-out to our very own eternal Cymene Howe :

    Social theory and the sociological imagination: an interview with Nigel Dodd (1 of 2)

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    Part I of our interview with Nigel Dodd, interviewed by Riad Azar. Nigel Dodd is Professor in the Sociology Department at the LSE. He obtained his PhD from the University of Cambridge in 1991 on the topic of Money in Social Theory, and lectured at the University of Liverpool before joining the LSE in 1995. Nigel’s main interests are in the sociology of money, economic sociology and classical and contemporary social thought. He is author of The Sociology of Money and Social Theory and Modernity (both published by Polity Press). His most recent book, The Social Life of Money, was published by Princeton University Press in September 2014

    What's bugging you? An update on the treatment of head lice infestation

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    Head lice infestation (pediculosis capitis) is a common problem in paediatric practice. It can cause considerable distress to children and their families and may lead to bullying and social stigmatisation. Therapy with "conventional" topical pediculicides with neurotoxic mode of action-such as malathion, permethrin, phenothrin and carbaryl-is increasingly associated with treatment failure as a result of the emergence of resistance within the parasite population. This review provides an overview of the natural history, clinical symptoms and diagnosis of head lice infestation. It also discusses general management principles and summarises the current data on novel treatment strategies, including wet combing, dimeticone, isopropyl myristate, benzyl alcohol, plant-based compounds and oral medication
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