1,721,175 research outputs found
The state of the art about etiopathogenetic models on breast implant associated–anaplastic large cell lymphoma (Bia‐alcl): A narrative review
Full text linkBackground: Breast‐implant‐associated anaplastic large cell lymphoma is a rare malignancy linked to texturized breast implants. Although many researchers focus on its etiopathogenesis, this topic is affected by a lack of evidence. Materials and Methods: A literature review about BIA‐ALCL was made. Results and conclusions: Although the incidence is reported between 1:355– 1:30.000, there is great attention to BIA‐ALCL. The incidence is uncertain due to many reasons. It may well be lower, due to inclusion in multiple databases as pointed out by the FDA and undiagnosed cases. The role of chronic inflammation, bacterial contamination, and mechanical forces was discussed. Clarification is needed to understand the mechanisms underlying the progression of alterations and mutations for BIA‐ALCL; new molecular analysis and pathogenetic models should be investigated
Submuscular and pre-pectoral ADM assisted immediate breast reconstruction: A literature review
Full text linkBackground and objectives: Breast cancer treatment has deeply changed in the last fifty years. Acellular dermal matrices (ADMs) were introduced for breast reconstruction, with encouraging results, but with conflicting reports too. The present paper aims to summarize the current data on breast reconstruction using acellular dermal matrices. Materials and Methods: We reviewed the literature regarding the use of ADM-assisted implant-based breast reconstruction. Results: The main techniques were analyzed and described. Conclusions: Several authors have recently reported positive results. Nevertheless, an increased complications’ rate has been reported by other authors. Higher cost compared to not-ADM-assisted breast reconstruction is another concern
DIETARY METHODS USING LACTOBACILLUS PARACASEI SUBSP. PARACASEI F19 AS NAPE-PLD GENE CARRIER FOR PRODUCING ON DEMAND PEA OR OEA AND RELATIVE BIOLOGICAL DIETARY COMPOSITIONS THEREOF
Full text linkMethod enabling to modulate and customize the production of active lipids involved in exerting an antagonistic action to local inflammation and in modulating the mast cell reactivity, comprising the administering to an host the probiotic Lactobacillus paracasei subsp. Paracasei F19, genetically modified with a nucleotide vector comprising a nucleic acid encoding the human N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD), in association with lipid substrates and precursors, to influence the enzymatic reactions of said probiotic agent in the host. The method is useful in the treatment of inflammatory bowel disorder and in the treatment of metabolic syndrome and for controlling of obesity
BIOLOGICAL COMPOSITION BASED ON ENGINEERED LACTOBACILLUS PARACASEI SUBSP. PARACASEI F19 FOR THE BIOSYNTHESIS OF CANNABINOIDS
No full textThe invention provides a method for producing therapeutic cannabinoids characterized by administering to an host the probiotic Lactobacillus Paracasei subsp. Paracasei F19, genetically modified to produce and secrete cannabinoids from Cannabis sativa, in association with caproic acid, able to establish the enzymatic reactions of the biosynthetic pathway leading to the production of cannabinoids directly in situ in said hos
Stem Cell Enriched Fat Grafts versus Autologous Fat Grafts in Reconstructive Surgery: Systematic Review and Meta-Analysis
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Letter on: “Artificial Intelligence: Enhancing Scientific Presentations in Aesthetic Surgery”
No full textAuthors discuss the paper titled “Artificial Intelligence: Enhancing Scientific Presentations in Aesthetic Surgery,” which explores how AI can improve the delivery and effectiveness of scientific presentations. They argue that the integration of AI in aesthetic surgery heralds significant possibilities for both academic and clinical applications. Currently, AI is already being utilized in various surgical aspects, including patient assessment, surgical planning, and intraoperative decision-making. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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