1,721,045 research outputs found
Conventional exercise interventions for adults with intellectual disabilities: A systematic review and meta-analysis
Exercise is a well-established therapeutic component in the management of a wide range of intellectual disabilities (IDs). Our aim was to appraise the effects of conventional forms of exercise on anthropometric, cardiovascular, and motor-functional profiles of adults with IDs. Four databases (PubMed/Scopus/PEDro/Cochrane) were searched to detect any randomized controlled trial (RCT) pertinent to conventional exercise trainings for adults with ID. Meta-analyses were being performed for studies reported results on the same outcome measures employing RevMan 5.3. Thirteen RCTs involving 556 participants (56.7% men) entered the qualitative synthesis and eleven the meta-analyses. The effect of exercise was superior to controls (no exercise prescription) on several cardiovascular variables (peak oxygen uptake, MD 2.89, 95%CI 0.35;5.42, I-2 = 69%; heart rate peak, MD 4.64, 95%CI 2.15;7.14, I-2 = 7%; maximal exercise capacity, SMD 0.55, 95%CI 0.03;1.08, I-2 = 67%; systolic blood pressure, MD -9.62, 95%CI -17.07;-2.18, I-2 = 40%), without differences in diastolic blood pressure and total cholesterol. None of the anthropometric and body composition variables, six-minute walking test distance and handgrip strength values revealed significant changes at the follow-up. In adults with IDs, conventional exercise training substantially improves cardiovascular fitness and exercise capacity, while it seems of limited effectiveness on anthropometric and body composition variables
The reasons why cardiologists should consider prematurity at birth and intrauterine growth retardation among risk factors
The survival percentage of infants born preterm has risen steadily worldwide thanks to the giant steps forward made in the field of perinatal (the period immediately after birth) and neonatal (the first 4 weeks of birth following delivery) medicine. However, prematurity at birth and consequent low birth weight still represent the major causes of neonatal morbidity and mortality. Infants born preterm are at high risk of developing neurological, ophthalmological, and gastrointestinal complications as well. Furthermore, extensive more recent epidemiological findings have demonstrated an increase in risk factors and a higher mortality rate due to cardiovascular causes in patients born preterm and/or with intrauterine growth restriction. The aim of this review is to provide scientific evidence about how the cardiovascular system may be negatively influenced by prematurity and by a low birth weight that should by rights be viewed as new cardiovascular risk factors. This condition is referred to as 'cardiovascular perinatal programming'. In the light of the above, an early, constant, and prolonged cardiovascular follow-up should be implemented in former preterm individuals
Myopericarditis in a Male Adolescent Following the Second Shot of COVID-19 Pfizer m-RNA Vaccine: Typical Example and Analysis of 110 Single Case Reports
One of the most powerful weapons against COVID-19 is vaccines. After the worldwide spread of the disease, m-RNA vaccines were authorized not only in adult patients, but also in children and adolescents aged 12–18. Since then, alarming reports of cases of myocarditis and/or pericarditis have been noted, primarily involving males after the second vaccine shot. A typical example of myopericarditis occurring in an adolescent a few days after the second shot of an m-RNA vaccine is described here. An in-depth review of all 110 single case reports published up to July 2022 with related features and outcomes is also presented. This is the first extensive analysis focused solely on a significant number of single case reports, which have usually been excluded from systematic reviews and meta-analyses carried out in the field. The analysis presented here confirms that most cases occurred in males after the second injection of an m-RNA vaccine. Cases were mild and responsive to the usual medical treatment. What is newly reported is that not only adolescents, but also older people, especially females, were affected by this adverse event
How predatory journals leak into PubMed
PubMed, MEDLINE and PubMed Central are all funded by the
National Library of Medicine but are different databases.
• PubMed has been reported to include some articles published in
predatory journals.
• MEDLINE and PubMed policies for the selection of journals for
database inclusion are slightly different.
• Weaknesses in the criteria and procedures for indexing journals in
PubMed Central may allow publications from predatory journals
to leak into PubMed.
• Closing these loopholes is necessary to protect the integrity of
reputable databases and safeguard biomedical research
Bridging the mortality gap: A new challenge in percutaneous coronary intervention for patients with cancer
Physical Activity Levels And Health-related Quality Of Life In Italian University Students
Predatory Open Access in Rehabilitation
Increasingly scholars and researchers are being solicited by predatory open access journals seeking manuscript submissions and abusing the author-pays model by charging authors with publishing fees without any or proper peer review. Such questionable editorial practices are threatening the reputation and credibility of scholarly publishing. To date, no investigation has been conducted on this phenomenon in the field of
rehabilitation. This study attempts to identify specific predatory journals operating in this field to quantify the phenomenon and its geographic distribution. Beall’s List has been used to this end which, although not perfect, is a comprehensive and up-to-date report of predatory publishers.
Of the 1113 publishers on the list, 59 journals were identified, for a total of 5610 published articles. The median number of articles published by each journal was 21, and the median amount of article processing charges was $499. Only 1 out of 59 journals was included in the Directory of Open Access Journals, whereas 7 (12%) were indexed by PubMed. Most of the publishers were based in India (36%) followed by the United States (25%) and Pakistan (5%), and 25% were without a verifiable address. The data indicate that the threat of predatory publishing in rehabilitation is real. Physiatrists, physiotherapists, researchers, and academics operating in this field are advised to use the tools available to recognize predatory practices before considering publishing in open access journals
Exercise intensity and energy expenditure during a mini-trampoline rebounding exercise session in overweight women
Objectives The purpose of this study was to estimate the exercise intensity and energy expenditure during a mini-trampoline rebounding training session in a group of overweight women to assess whether such fitness activity meets the guidelines for exercise prescription in adults of the American College of Sports Medicine (ACSM) and whether it can be recommended for an overweight female population. Equipment and methods To achieve the aims of our study, eighteen overweight women (36.7 ± 10.6 years, BMI: 26.8 ± 1.6 kg/m2), were enrolled. All the participants underwent a maximal cardiopulmonary exercise test and the main physiological variables were recorded. Afterwards, the subjects performed a mini-trampoline rebounding exercise session where exercise intensity and energy expenditure were measured with a heart rate monitor, a rating perceived exertion scale and a portable armband device, respectively. Successively, the physiological responses obtained from these two activities were compared. Results The average heart rate throughout the mini-trampoline exercise session, lasting 46.1 ± 5.0 min, was 132.3 ± 7.7 bpm, corresponding to 72.2 ± 3.3% of that obtained in the preliminary maximal test. The estimated energy expenditure of participants to mini-trampoline rebounding exercise session was 6.9 ± 0.8 kcal/min, corresponding to a total of 317.3 ± 45.7 kcal for the duration of the entire session. Conclusions Our results showed that mini-trampoline rebounding exercise is a vigorous physical activity, which can be identified as an effective way to achieve an optimal level of training, as indicated by the ACSM guidelines
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