1,721,001 research outputs found
New evidencies in PDD pathogenesis: can ganglioside sensitization satisfy Koch's postulates?
No full textAlternative medicine and non-invasive therapies for the treatment of Meniere’s disease.
No full textCharacterized by recurrent episodes of tinnitus, acute vertigo, sensorineural hearing loss and aural fullness, Ménière's disease is known for its debilitating impact on quality of life. Although the etiology and pathogenesis remain largely unclear, the most plausible hypothesis ascribes to endolymphatic hydrops abnormal fluctuations in the pressure of inner ear, which would be responsible for alterations in receptor elements. The management of Ménière's disease is controversial, consequently itstreatment is currently empirical and the therapies are aimed at controlling the symptoms.
The purpose of this paper was a review of the literature on complementary and alternative (CAM) methods currently available to cope with this disease. The control of water intake may be the simpler and more convenient procedure for patients. Even the adaptation of the lifestyle and the treatment of anxiety appear to be helpful. Nutrition education can improve the results of medical treatment: dietary protocols often include low-sodium diet and reduction of caffeine, nicotine, and carbohydrates intake. Some studies have assessed the impact of the ingestion of specially processed cereals (SPC) optimized to enhance the synthesis of endogenus antisecretory factor (AF). The AF acts as a modulator of water and ion transport by regulating the homeostasis of chlorides. The intake of Omega-3 seems to satisfy all necessary requirements to obtain a correct homeostasis of the inner ear. Finally, the repetitive application of excess pressure in the middle ear (Meniett device), virtual reality and acupuncture have been shown to induce improvements in patients with Ménière's disease
PDD: a possibile new therapeutical approach!
No full textProventricular Dilatation Disease (PDD) is a deadly wasting syndrome that affl icts wild and domesticated birds and parrots worldwide. The
symptoms of PDD are varied, and its outcome is fatal. There is currently no treatment for PDD. The Avian Bornavirus (ABV) is the fi rst candidate
in the list of the aetiological agent of PDD. However, the virus was regularly found in clinically healthy birds. This implicates that additional
factors for the development of PDD are likely. In our previous studies we have demonstrated that i) sera of PDD-affected parrots showed
auto-antibodies to gangliosides; ii) these auto-antibodies are localized in the crop or gastrointestinal ganglia of parrots that, in some cases, are
positive also for ABV PCR or P40 antibodies. In our opinion an immunomodulating therapeutical approach is request, for host’s gangliosides
antigens desensitization. We report preliminary data regarding a new therapy performed in severely affected birds
New acqusitions in PDD pathogenesis; an innovative test to reveal anti-ganglioside antibodies in sera of affected parrots.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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