4,885 research outputs found
Cummins, K F (Kevin Francis), NX36146
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/379994Surname: CUMMINS
Given Name(s) or Initials: K F (KEVIN FRANCIS)
Military Service Number or Last Known Location: NX36146
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 32425193806
Item: [2016.0049.12287] "Cummins, K F (Kevin Francis), NX36146
Agent-based Traffic Operator Training Environments for Evacuation Scenarios
No full textRealistic simulation environments play a vital role in the effective training of traffic controllers to respond to large-scale events such as natural disasters or terrorist threats. BAE SYSTEMS is developing a training environment that comprises of: a physical traffic control centre environment, a 3D visualisation and a traffic behaviour model. In this paper, we describe how an agent-based approach has been essential in the development of the traffic operator training environment, especially for constructing the required behavioural models. The simulator has been applied to an evacuation scenario, for which an agent-based model has been developed which models a variety of relevant driver evacuation behaviours. These unusual behaviours have been observed occurring in real-life evacuations but to date have not been incorporated in traffic simulators. In addition, our agent-based approach includes flexibility within the simulator to respond to the variety of decisions traffic controllers can make, as well as achieving a strong degree of control for the scenario manager
Therapist ratings of therapeutic alliance and their connections to psychotherapy outcome:
No full textThe present study was designed to build upon extant research in the area of the working alliance in psychotherapy and its relationship to treatment outcome. Utilizing a detailed archival data set and following upon a previous study that drew from this same set, the present study searched for significant interaction between treatment outcome and aspects of the working alliance as seen and rated by psychotherapists treating individual members of an actual clinical population, for a time-limited (30 session) treatment, in one of three different treatment conditions (varying by theoretical orientation, clinical emphasis, and/or technical approach). Therapy outcome was signified by the use of residual gains scores calculated from client responses to multiple assessment instruments, with the scores representing measures of the subject’s post-treatment (1) symptom picture and (2) level of interpersonal problems. The study was designed to detect significant associations between these outcome measures and: the strength of the therapeutic alliance; the “shape” of the alliance as represented by plotting shifts in alliance scores over the course of 30 therapy sessions; and the presence/absence, severity and quantity of alliance ruptures and related phenomena (e.g., alliance ruptures either repaired or unrepaired). Analysis of the data yielded findings consistent with those generally seen in the research literature – i.e., stronger therapeutic alliance was associated with better treatment outcome – as well as findings indicating a differential impact on therapy outcome of alliance ruptures and related phenomena. In addition, therapy treatment condition was found to be associated with whether certain rupture-related phenomena were correlated with therapy outcome. The implications of these findings are discussed, as well as the utility of these findings for the practitioner, the import of using therapists’ ratings of therapeutic alliance, the limitations of the present study, and directions for further research.Psy.DIncludes bibliographical references (p. 124-127)by Kevin F. Gillett
A discussion of pneumatology and the linguistic turn to practice, with reference to Kevin Vanhoozer’s canonical-linguistic approach to Christian theology
No full textThis dissertation assesses the pneumatological implications of Kevin Vanhoozer’s canonical-linguistic approach to Christian theology, in the context of the wider issue of recent interest in re-conceiving the cultural-linguistic approach to theology through a description of Christian practice in directly pneumatological terms. I seek to welcome Vanhoozer’s communicative-act description of the authority and identity of Scripture as God’s written Word, and the way in which this description affirms the key insights of the linguistic turn to practice whilst maintaining the normativity of Scripture (as divine communicative action) to Christian practice (participation in that action). My concern is that Vanhoozer constructs his proposal around a Triune model of divine communicative action that I believe has pneumatological shortcomings. In particular, I think that the importance of God’s personal presence by the Holy Spirit is hard to convey within Vanhoozer’s canonical-linguistic theology. I argue that this matters because answers to the epistemological and hermeneutical questions that Vanhoozer is seeking to address require a fully Trinitarian theology that draws upon the significance of God’s indwelling presence by his Spirit. Such pneumatology is vital to the description of both the ontological distinction between God and creation and the divine-human relation in the economy of salvation centred upon the life, death and resurrection of Jesus Christ. It should be part of a fully Trinitarian theology that enables us to address questions of epistemology, hermeneutics and agency without making those concerns appear to determine the nature of salvation or the being of God. In making this argument, I draw in particular upon Colin Gunton’s discussion of Karl Barth’s triune model of divine self-revelation and Gordon Fee’s exegesis of Paul’s teaching on the Holy Spirit
Truth and Robustness in Cross-country Growth Regressions
No full textThe work of Levine and Renelt (1992) and Sala-i-Martin (1997a, b) which attempted to test the robustness of various determinants of growth rates of per capita GDP among countries using two variants of Edward Leamerâ??s extreme-bounds analysis is reexamined. In a realistic Monte Carlo experiment in which the universe of potential determinants is drawn from those in Levine and Reneltâ??s study, both versions of the extreme-bounds analysis are evaluated for their ability to recover the true specification. Levine and Reneltâ??s method is shown to have low size and extremely low power: nothing is robust; while Sala-i-Martinâ??s method is shown to have high size and high power: it is undiscriminating. Both methods are compared to a cross-sectional version of the generalto-specific search methodology associated with the LSE approach to econometrics. It is shown to have size near nominal size and high power. Sala-i-Martinâ??s method and the general-to-specific method are then applied to the actual data from the original two studies. The results are consistent with the Monte Carlo results and are suggestive that the factors that most affect differences of growth rates are ones that are beyond the control of policymakers.growth, cross-country growth regressions, extreme-bounds analysis, general-to-specific specification search
Author Correction: Global diversity and biogeography of bacterial communities in wastewater treatment plants (Nature Microbiology, (2019), 4, 7, (1183-1195), 10.1038/s41564-019-0426-5)
No full textIn the version of this Article originally published, the name of the author ‘Mathew Robert Brown’ was incorrectly written as ‘Mathew Brown’ in the main author list and as ‘Matthew Brown’ in the Global Water Microbiome Consortium list. In addition, in the Global Water Microbiome Consortium list, the names of the authors ‘Kevin F. Boehnke’, ‘Janeth Sanabria’ and ‘Adalberto Noyola’ were incorrectly written as ‘Kevin Boehnke’, ‘Janeth Sanabria Gómez’ and ‘Adalberto Noyola Robles’, respectively. The names have now been corrected and the author initials in the author contributions section updated accordingly
Hacked: a radical approach to hacker culture and crime/ Kevin F. Steinmetz.
No full textIncludes bibliographical references and index.Acknowledgments -- Introduction: toward a radical criminology of hackers -- Setting the stage -- The front end of hacking -- Craft(y)ness -- On authority and protocol -- The radical turn -- The [hack] mode of production -- Crafting a crackdown -- Conclusion -- Appendix: field research lists -- Notes -- References -- Index -- About the author.1 online resource
THE REGULATION OF MICROTUBULE DYNAMICS BY +TIPS AND CROSS-LINKING PROTEINS
No full textABSTRACT
Rebecca Cressey Adikes: The regulation of microtubule dynamics by
+TIPs and cross-linking proteins
(Under the supervision of Kevin C. Slep)
The dynamic cytoskeleton is composed of distinct filamentous polymer networks. These polymers create highly dynamic scaffolds for many cellular processes in eukaryotes. The polymers provide tracks for cargo transport, mechanically stabilize the cell, establish cell polarity, and are central components of the force-generating machinery required for cell division. In order to perform these various cellular tasks the polymers undergo spatially and temporally regulated assembly and disassembly. Understanding the spatial and temporal regulation of these cellular polymers is essential to understanding cell function.
Here, we investigate the spatial and temporal regulation of two polymer networks in cells, the microtubule (MT) and F-actin networks. We developed and employed methods to alter protein targeting and localization using a novel optogenetic approach and a classical structural/functional approach to understand how the recruitment of effectors of these networks alters network dynamics.
We developed and employed an optogenetic tool to gain insight into the msec/sec resolution time regime of MT-F-actin cross-linking. This allowed us to uncover key immediate down stream cellular events of cross-linking including decreased MT comet velocities on the sec time scale and an exclusion of MT from the cell periphery on the min-hr time scale. Additionally, using more classical structure/function based experiments, we were able to alter protein targeting using protein domains and through mutation of the protein sequence by just 1-3Doctor of Philosoph
Real Options Models of the Firm, Capacity Overhang, and the Cross-Section of Stock Returns
No full textWe use a stochastic frontier model to obtain a stock-level estimate of the difference between a firm's installed production capacity and its optimal capacity. We show that this “capacity overhang” estimate relates significantly negatively to the cross-section of stock returns, even when controlling for popular pricing factors. The negative relation persists among small and large stocks, stocks with more or less reversible investments, and in good and bad economic states. Capacity overhang helps explain momentum and profitability anomalies, but not value and investment anomalies. Our evidence supports real options models of the firm featuring valuable divestment options
Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker
No full textWe developed a novel optogenetic tool, SxIP–improved light-inducible dimer (iLID), to facilitate the reversible recruitment of factors to microtubule (MT) plus ends in an end-binding protein–dependent manner using blue light. We show that SxIP-iLID can track MT plus ends and recruit tgRFP-SspB upon blue light activation. We used this system to investigate the effects of cross-linking MT plus ends and F-actin in Drosophila melanogaster S2 cells to gain insight into spectraplakin function and mechanism. We show that SxIP-iLID can be used to temporally recruit an F-actin binding domain to MT plus ends and cross-link the MT and F-actin networks. Cross-linking decreases MT growth velocities and generates a peripheral MT exclusion zone. SxIP-iLID facilitates the general recruitment of specific factors to MT plus ends with temporal control enabling researchers to systematically regulate MT plus end dynamics and probe MT plus end function in many biological processes.</jats:p
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