67 research outputs found
sj-docx-1-msj-10.1177_13524585211044479 – Supplemental material for Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study
No full textSupplemental material, sj-docx-1-msj-10.1177_13524585211044479 for Rapid and sustained B-cell depletion with subcutaneous ofatumumab in relapsing multiple sclerosis: APLIOS, a randomized phase-2 study by Amit Bar-Or, Heinz Wiendl, Xavier Montalban, Enrique Alvarez, Maria Davydovskaya, Silvia R Delgado, Evgeniy P Evdoshenko, Natasa Giedraitiene, Katrin Gross-Paju, Sulev Haldre, Craig E Herrman, Guillermo Izquierdo, Guntis Karelis, Fritz Leutmezer, Miroslav Mares, Jose E Meca-Lallana, Dalia Mickeviciene, Jacqueline Nicholas, Derrick S Robertson, Denis V Sazonov, Kenneth Sharlin, Bharathy Sundaram, Natalia Totolyan, Marta Vachova, Martin Valis, Morten Bagger, Dieter A Häring, Inga Ludwig, Roman Willi, Martin Zalesak, Wendy Su, Martin Merschhemke and Edward J Fox in Multiple Sclerosis Journal</p
Implementing Research Cyberinfrastructure for the 21st Century
No full text2 online resources (PDF files): Final report and Poster presentationAs a result of innovative partnerships between the Office of Information Technology, collegiate units, and other Central units, outstanding technological support systems for administrative and academic needs have been developed to serve faculty, staff and students. Central and local IT support staffs maintain servers and desktop computers to ensure availability and security of information technology tools and resources. The University’s Digital Media Center, along with academic technology support staffs in local units, provides a variety of services to instructors and students using technology in teaching and learning. .
Dramatic advances in information technology make way for exciting new opportunities for research as well. New technologies allow projects to span disciplines and institutions, enabling researchers to seek new answers to critical questions in ways that were impossible just years or even months ago. Indeed, research computing is a top priority for leading universities and research institutions around the globe; furthermore, cyberinfrastructure is seen as a key factor in securing research funding and attracting and retaining top faculty and students.
The expanded research agendas in many disciplines are now outpacing the computing resources available to individual researchers, departments, or even institutions. Enabling this research requires large-scale investments in high-performance computing, storage and networking, as well as the development of cyberinfrastructure to integrate these components into a meaningful whole.
Cyberinfrastructure includes the instruments, sensors, high performance computational systems, massive storage systems, data resources, and visualization facilities, tied together by high speed networks and made to work together by advanced software to accomplish goals that would not be possible by any single information technology system. It also includes the people, processes, training, security, policies, and capabilities to sustain the systems and networks over time. Implementing cyberinfrastructure requires a high level of coordination and collaboration between researchers and an information technology workforce with expertise in scientific computing.President's Emerging Leadership ProgramAnderson, Tracy; Gjerdinge, Craig; Herrman, Bryan; Himes, Katherine; Johnston, Lisa R. (2009). Implementing Research Cyberinfrastructure for the 21st Century. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/91772
David Graeber: Purity, Alienation and Dignity
No full textDavid Graeber wrote about debt, jobs and the negative effects of globalization. He was an American anthropologist, anarchist activist, and was an author known for his books Debt: The First 5000 Years, The Utopia of Rules and Bullshit Jobs: A Theory. A professor of anthropology at the London School of Economics, he passed away 2 September 2020, at age 59
Fábulas Bilingües. The Bilingual Series
No full textThis story does not strike me as being a fable in the traditional sense. However, it is a delightful story. Martina is a beautiful ant. Many wooers come beneath her balcony: cat, duck, dog, rooster, frog, bull, pig, and finally the hoped for mouse Pérez. To each she answers Maybe yes, maybe no. How will you speak to me in the future? Pérez wins her heart and they marry. Alas, Pérez carelessly falls into a Christmas rice pudding that Martina is making for him. Everyone runs to Martina's house. Pérez is saved in the nick of time, and everyone stays to celebrate Christmas. The picture of Pérez floating in the pudding (25) is excellent! And what is one to learn from this story?Language note: Bilingual: English/SpanishOriginal language: spaMarjorie E. Herrman
Interventions in the Health and Non-health Sectors Aimed at Promoting Mental Health
No full textThe impact of social determinants on women's mental health is becoming clearer worldwide. Poverty, violence and communal insecurity are among the main challenges to women's mental health and the health of their families. Depression is one of the most common mental disorders experienced by women. It typically has an early onset in life and is more frequently found in women made vulnerable by trauma.Improving mental health for women and girls requires early intervention for depression and other mental disorders; with gender sensitive clinical care and support for recovery in primary health care, and mother, child and reproductive health settings. Early intervention in primary health care and collaboration with patients and family carers encourage integration of mental health with the health care system, in turn protective of human rights.In addition, gender equity and observance of human rights need to be embedded in policy and practice in health and non-health sectors to ensure that women's mental health is promoted and mental illnesses adequately prevented and treated. Effective promotion of mental health and prevention of mental disorders is possible in countries of all income levels.Disclosure of interestThe author has not supplied his declaration of competing interest.</jats:sec
Philosophy and Meditation
No full textPreview:
/Review: Michael Webb, The Whole at Once: A Conversation on Meaning (Austin,TX: Fire Hill Press, 2020), 244 pages./
This is a book about a phenomenological challenge: to reach the depths of meaning. It relies principally on becoming aware of the self and of the core essence of wholes, be they collections of objects or sentences or ideas. But meaning is the end point constituting, according to the author, a drive more powerful even than the will to live (WO, 137). It lies beyond any given perspective. The work is presented as a dialogue between student and master; its 244 pages actually make for a quick and relatively easy read, not burdening the reader with jargon. It intends to be a popular presentation but without skimping on issues of relevance to philosophy
Philosophy and Meditation
No full textPreview: /Review: Michael Webb, The Whole at Once: A Conversation on Meaning, 244 pages./ This is a book about a phenomenological challenge: to reach the depths of meaning. It relies principally on becoming aware of the self and of the core essence of wholes, be they collections of objects or sentences or ideas. But meaning is the end point constituting, according to the author, a drive more powerful even than the will to live. It lies beyond any given perspective. The work is presented as a dialogue between student and master; its 244 pages actually make for a quick and relatively easy read, not burdening the reader with jargon. It intends to be a popular presentation but without skimping on issues of relevance to philosophy
Companions on the Journey: Symbolic Interaction in Helping Relationships and the Development of Spirituality For Young Adult Catholics
No full textMany young adults experience a shift in faith understanding and experiences after adolescence. This study sought to uncover the communicative nature of helping relationships in spiritual contexts. The author explored spiritual helping relationships as a comparative form of mentoring, placing focus on models offered by Buell (2004). Utilizing Symbolic Interaction, the study examined co-created meaning and developed meaning among young adults and helpers. The qualitative project utilized online open-ended survey instruments specifically designed for young adult Catholics and helpers which examined the value, role, and scope of spirituality in the lives of participants. Emergent themes included prayer life, discussion of spirituality, spiritual influences, and communication in helping relationships. Utilizing definitions of mentoring models indicated by Buell (2004) in her research, this research sought to provide comparative models of spiritual helping relationships
Embedding effective depression care: using theory for primary care organisational and systems change
No full textBackground: depression and related disorders represent a significant part of general practitioners (GPs) daily work. Implementing the evidence about what works for depression care into routine practice presents a challenge for researchers and service designers. The emerging consensus is that the transfer of efficacious interventions into routine practice is strongly linked to how well the interventions are based upon theory and take into account the contextual factors of the setting into which they are to be transferred. We set out to develop a conceptual framework to guide change and the implementation of best practice depression care in the primary care setting.Methods: we used a mixed method, observational approach to gather data about routine depression care in a range of primary care settings via: audit of electronic health records; observation of routine clinical care; and structured, facilitated whole of organisation meetings. Audit data were summarised using simple descriptive statistics. Observational data were collected using field notes. Organisational meetings were audio taped and transcribed. All the data sets were grouped, by organisation, and considered as a whole case. Normalisation Process Theory (NPT) was identified as an analytical theory to guide the conceptual framework development.Results: five privately owned primary care organisations (general practices) and one community health centre took part over the course of 18 months. We successfully developed a conceptual framework for implementing an effective model of depression care based on the four constructs of NPT: coherence, which proposes that depression work requires the conceptualisation of boundaries of who is depressed and who is not depressed and techniques for dealing with diffuseness; cognitive participation, which proposes that depression work requires engagement with a shared set of techniques that deal with depression as a health problem; collective action, which proposes that agreement is reached about how care is organised; and reflexive monitoring, which proposes that depression work requires agreement about how depression work will be monitored at the patient and practice level. We describe how these constructs can be used to guide the design and implementation of effective depression care in a way that can take account of contextual differences.Conclusions: ideas about what is required for an effective model and system of depression care in primary care need to be accompanied by theoretically informed frameworks that consider how these can be implemented. The conceptual framework we have presented can be used to guide organisational and system change to develop common language around each construct between policy makers, service users, professionals, and researchers. This shared understanding across groups is fundamental to the effective implementation of change in primary care for depressio
HYPERFINE STRUCTURE IN THE MICROWAVE SPECTRUM OF
No full text Supported by the National Science Foundation, and by the Joint Services (U. S. Army, Air Force Office of Scientific Research, and Office of Naval Research). Present address: Institute for Molecular Physics, University of Maryland. G. Herrman, J. Chem. Phys. 29, 875 (1958).Author Institution: Columbia Radiation Laboratory, Columbia UniversityHyperfine structure in the rotation-inversion transition of deuterated ammonia at 18,807.7 Mc/sec has been studied with a beam maser microwave spectrometer giving a linewidth of 6 kc/sec. All details of the observed hfs have been accounted for in terms of the various quadrupole, spin-rotation, and spin-spin interactions of the four nuclei. For the quadrupole coupling constant of the deuteron along the N-D bond direction we find that , and hence for the second derivative of the potential . This is slightly higher than the value for the coupling constant of kc/sec found by Herrman from the inversion spectrum of . For the spin-rotation constants of the protons we find that , and
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