72,311 research outputs found
Cox, H R T, QX8836
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/379279Surname: COX
Given Name(s) or Initials: H R T
Military Service Number or Last Known Location: QX8836
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 36319193091
Item: [2016.0049.11572] "Cox, H R T, QX8836
Cox, N T R, VX8943
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/379297Surname: COX
Given Name(s) or Initials: N T R
Military Service Number or Last Known Location: VX8943
Missing, Wounded and Prisoner of War Enquiry Card Index Number: 4827193109
Item: [2016.0049.11590] "Cox, N T R, VX8943
Cox Thompson
Airmen grouped in front of aircraft - P-40 Curtiss Kittyhawk. No. 77 Squadron, Royal Australian Air Force. Sergeant G. B. Rich; Sergeant M. Holdsworth; Sergeant T. P. Power; Flying Officer John G. Gorton (later Prime Minister of Australia); Pilot Officer C. I. Winter-Irving; Pilot Officer J. A. T. Hodgkinson; Sergeant C. Laing; Flying Officer G. Gratton. Front row: Sergeant P. R. McEwen; Flying Officer B. Wilson; Flying Officer J. C. Hastwell; Flight Lieutenant George Shave, Flight Commander; Flight Lieutenant R. C. Kimpton.Thompson, Cox.Date:1942-1
Selective COX-2 inhibitors and risk of myocardial infarction
Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids. Recently some coxibs, which were designed to exploit the advantageous effects of non- steroidal anti-inflammatory drugs while evading their side effects, have been reported to increase the risk of myocardial infarction and atherothrombotic events. This has led to the withdrawal of rofecoxib from global markets, and warnings have been issued by drug authorities about similar events during the use of celecoxib or valdecoxib/ parecoxib, bringing about questions of an inherent atherothrombotic risk of all coxibs and consequences that should be drawn by health care professionals. These questions need to be addressed in light of the known effects of selective inhibition of COX- 2 on the cardiovascular system. Although COX- 2, in contrast to the cyclooxygenase-1 ( COX- 1) isoform, is regarded as an inducible enzyme that only has a role in pathophysiological processes like pain and inflammation, experimental and clinical studies have shown that COX- 2 is constitutively expressed in tissues like the kidney or vascular endothelium, where it executes important physiological functions. COX- 2- dependent formation of prostanoids not only results in the mediation of pain or inflammatory signals but also in the maintenance of vascular integrity. Especially prostacyclin ( PGI(2)), which exerts vasodilatory and antiplatelet properties, is formed to a significant extent by COX- 2, and its levels are reduced to less than half of normal when COX- 2 is inhibited. This review outlines the rationale for the development of selective COX- 2 inhibitors and the pathophysiological consequences of selective inhibition of COX- 2 with special regard to vasoactive prostaglandins. It describes coxibs that are currently available, evaluates the current knowledge on the risk of atherothrombotic events associated with their intake and critically discusses the consequences that should be drawn from these insights. Copyright (C) 2005 S. Karger AG, Basel
Implementation of complex interactions in a Cox regression framework
The standard Cox proportional hazards model has been extended by functionally describable interaction terms. The first of which are related to neural networks by adopting the idea of transforming sums of weighted covariables by means of a logistic function. A class of reasonable weight combinations within the logistic transformation is described. Apart from the standard covariable product interaction, a product of logistically transformed covariables has also been included in the analysis of performance of the new terms. An algorithm combining likelihood ratio tests and AIC criterion has been defined for model choice. The critical values of the likelihood ratio test statistics had to be corrected in order to guarantee a maximum type I error of 5% for each interaction term. The new class of interaction terms allows interpretation of functional relationships between covariables with more flexibility and can easily be implemented in standard software packages
Concentration in Knowledge Output: A case of Economics Journals
This paper assesses the degree of author concentration in seven economics journals, which were published in India during 1990-2002. To measure the degree of author concentration, Lotka's Law was used. Moreover, we also make an exploratory analysis of the geographic, economics subfield and institutional concentration in 704 economics journals. An important finding of this paper is that specialized journals in the sample report the highest degree of author concentration. This result is quite similar to the findings by Cox and Chung (1991). Furthermore, there are several instances showing that the journals lean towards certain norms; this may affect the flow of innovative ideas into economics. We conclude that a knowledge activity, involving the high degree of concentration and a biased publication process, may affect the flow of new ideas into the discipline.Concentration, Lotka's Law
BOX-COX TRANSFORMATIONS AND ERROR TERM SPECIFICATION IN DEMAND MODELS
This paper analyzes the influence of error-term specification and functional form on a quarterly demand model for beef. The Box-Cox transformation is used to generalize the functional form while the equation error term is postulated to be both heteroskedastic and autoregressive. Results indicated that both functional form and error-term specification can play a major role in elasticity estimation, elasticity behavior, and hypothesis testing.Demand and Price Analysis,
Generating Survival Times to Simulate Cox Proportional Hazards Models
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression coefficients and the simulated random errors. Thus, the response variable can be generated from the regression function, once the regression coefficients and the error distribution are specified. However, in the Cox model, which is formulated via the hazard function, the effect of the covariates have to be translated from the hazards to the survival times, because the usual software packages for estimation of Cox models require the individual survival time data. A general formula describing the relation between the hazard and the corresponding survival time of the Cox model is derived. It is shown how the exponential, the Weibull and the Gompertz distribution can be used to generate appropriate survival times for simulation studies. Additionally, the general relation between hazard and survival time can be used to develop own distributions for special situations and to handle flexibly parameterized proportional hazards models. The use of other distributions than the exponential distribution only is indispensable to investigate the characteristics of the Cox proportional hazards model, especially in non-standard situations, where the partial likelihood depends on the baseline hazard
1993-1994 T. R. Pearson
T. R. Pearson, a.k.a. Rick Gavin, was born in Winston-Salem, North Carolina. He was a student at North Carolina State University, where he gained a B.A. and M.A. in English. He was the first recipient of the John and Renée Grisham Writer in Residence Fellowship. He is the acclaimed author of fourteen novels, including A Short History of a Small Place and Warwolf, and a dozen screenplays. Top of the Rock is his fifth nonfiction book. He lives in Virginia and Brooklyn, New York. (Photo credit: Marian Young)https://egrove.olemiss.edu/grisham_res/1026/thumbnail.jp
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