177,458 research outputs found

    M. d'Ischia, C. Costantini, G. Prota. Reaction of dopamine with malondialdehyde: a possible underlying event in Parkinson's disease.

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    Under physiologically relevant conditions, malondialdehyde reacts with the neurotransmitter dopamine to give three major adducts that were identified as the enaminal 1, the dihydropyridine 2 and the novel oxaazabicyclo[3.3.1]nonadiene 3

    Polynomial cubic splines with tension properties

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    In this paper we present a new class of spline functions with tension properties. These splines are composed by polynomial cubic pieces and therefore are conformal to the standard, NURBS based CAD/CAM systems

    Obliquely reflecting Brownian motion in nonpolyhedral, piecewise smooth cones, with an example of application to diffusion approximation of bandwidth-sharing queues

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    This work gives sufficient conditions for uniqueness in distribution of semimartingale, obliquely reflectingBrownianmotion in a nonpolyhedral, piecewise C^2 cone, with radially constant, Lipschitz continuous direction of reflection on each face. The conditions are shown to be verified by the conjectured diffusion approximation to the workload in a class of bandwidth-sharing networks, thus ensuring that the conjectured limit is uniquely characterized. This is an essential step in proving the diffusion approximation. This uniqueness result is made possible by replacing the Krein–Rutman theorem used by Kwon and Williams (1993) in a smooth cone with the recent reverse ergodic theorem for inhomogeneous, killedMarkov chains of Costantini and Kurtz (Ann Appl Probab, 2024. https://doi.org/10.1214/23-AAP2047; Stoch ProcessAppl 170:104295, 2024. https://doi.org/10.1016/j.spa.2024.104295)

    Il nuovo contratto

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    Promesse vincolanti, atti unilaterali e contratti Offerta e accettazione La causa: qualificazione e liceità degli accordi Diritti e obblighi dei terzi Prova e interpretazione del contratto Le difese contro la vincolatività del contratto La giustizia contrattuale La buona fede Le tutele del consumatore L’inadempimento del contratto I rimedi contro l’inadempimento Il danno contrattuale Il danno contrattuale non patrimonial

    Manuale del nuovo contratto

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    1. Promesse vincolanti, atti unilaterali e contratti ad una sola dichiarazione 2. Offerta e accettazione 3. La causa: qualificazione e liceità degli accordi 4. Prova e interpretazione del contratto 5. Le difese contro la vincolatività del contratto 6. Le clausole e i temrini contrattual

    On the infimum of the Hausdorff metric topologies

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    Given a metrizable space X and a compatible metric d, one defines the Hausdorff metric topology Hd and the upper and lower Hausdorff topologies corresponding to d, Hd+ and Hd- respectively, on the collection C(X) of all closed subsets of X. In this paper we consider the infima τ, τ+ and τ−, of the topologies Hd, Hd+ and Hd- respectively, where d runs over the set M(X) of all compatible metrics on X. These topologies are sequential, that is, they are completely characterized by convergent sequences. In particular, the topologies τ+ and τ− are investigated in detail: a suitable topology U+ is defined which has the same convergent sequences as τ+, and the lower Vietoris topology V− plays a similar role with respect to τ−. We show that, in general, the equality τ = τ+ ∨ τ− does not hold. We also show that τ is a T2-topology on C(X) if and only if X is locally compact

    Climate and Pedoclimate of Italy

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    In Chap. 2 , the role played by the factors of soil formation in Italy is examined by different authors. Edoardo Costantini, Maria Fantappie ́ , and Giovanni L’Abate explore the potential strong influence of climate on soil nature and distribution. In spite of being placed in the middle of the temperate zone of the boreal hemisphere, the elongated shape of the Italian peninsula, stretching along 11 parallels in the middle of the Mediterranean sea, and the presence of two morphological barriers, the Alps and the Apennines, cause great local climatic variations, to an extent that they are much more important than means. In fact, long-term mean annual air temperature for the whole country is 12.6 C and total annual precipitation 932.5 mm, but the differences between minima and maxima span 30 C and 1,800 mm, respectively. Actually, in Italy there are 14 of the 35 climatic regions occurring in Europe. A general climatic change occurred in Italy in the period 1961–2000, with a general reduction of the mean annual precipitations, thenumber of rainy days, and a general increase of the mean air temperatures. The climate change had some influence on soil organic carbon variations, especially in the meadows and arable lands located in areas where a moderate or high decrease of the mean total annual precipitation value (\-100 mm) and a moderate to high increase of mean air temperature ([0.62 C) occurred

    Decomposition of topologies on lattices and hyperspaces

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    The notion of decomposable topology is introduced in a partially ordered set, and in particular in the lattice C(X) of all closed subsets (ordered by reverse inclusion) of a topological space X, which is also called the hyperspace of X. This notion is closely related to the concepts, defined in the same framework, of lower, upper and strong upper topology. In this paper we investigate decomposability and unique decomposability of the main hyperspace topologies, and of topologies which are defined on some quite natural lattices or semilattices

    Looking ahead: anticipatory gaze and motor ability in infancy

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    The present study asks when infants are able to selectively anticipate the goals of observed actions, and how this ability relates to infants' own abilities to produce those specific actions. Using eye-tracking technology to measure on-line anticipation, 6-, 8- and 10-month-old infants and a control group of adults were tested while observing an adult reach with a whole hand grasp, a precision grasp or a closed fist towards one of two different sized objects. The same infants were also given a comparable action production task. All infants showed proactive gaze to the whole hand grasps, with increased degrees of proactivity in the older groups. Gaze proactivity to the precision grasps, however, was present from 8 months of age. Moreover, the infants' ability in performing precision grasping strongly predicted their ability in using the actor's hand shape cues to differentially anticipate the goal of the observed action, even when age was partialled out. The results are discussed in terms of the specificity of action anticipation, and the fine-grained relationship between action production and action perception
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