1,721,036 research outputs found
Multimodal imaging of peripheral myelinated retinal nerve fiber layers without optic disk involvement
No full textDemonstration of Choroidal Neovascularization Associated With an Intraretinal Lesion on Indocyanine Green Angiography Independent of Choroidal New Vessel on Optical Coherence Tomography
No full textResolution of vitreomacular traction and pigment epithelium detachment
No full textPurpose: To report a case of spontaneous combined resolution of vitreomacular traction (VMT) and pigment epithelial detachment (PED). Methods: A 70-year-old woman presented with a 10-day history of metamorphopsia in her right eye. Medical history was unremarkable. The patient underwent a complete ophthalmic examination. Best-corrected visual acuity (BCVA) was 20/50 in the right eye. Fundus examination, fluorescein angiography, indocyanine green angiography, and optical coherence tomography (OCT) revealed a shallow elevated area with irregular edges suggestive of drusenoid avascular PED associated with VMT. Results: During the follow-up, OCT showed combined resolution of VMT and PED with almost complete normalization of the outer retinal layers; BCVA increased to 20/40. Conclusions: The temporal sequence of events in our case strongly suggests that the spontaneous resolution of PED could be the consequence of or could be favorably influenced by the VMT resolution
Spontaneous retinal pigment epithelium tear in geographic atrophy
No full textPurpose. - To report two cases of spontaneous retinal pigment epithelial (RPE) tears occurring in two patients affected with geographic atrophy (GA) due to non-exudative age-related macular degeneration (AMD). Case report. - Two patients (a 79-year-old man and a 71-year-old woman) presented to our department with progressive visual loss. The man had a best-corrected visual acuity (BCVA) of 20/100 in the right eye (RE) and 20/50 in the left eye (LE); the woman had a BCVA of 20/200 in the RE and 20/160 in the LE. Upon complete ophthalmologic examination, revealing a large area of atrophy (> 175 mu m in diameter) along with pigmentary changes, calcified drusen and no choroidal neovascularization (CNV) in either eye, the patients were diagnosed with GA due to non-exudative AMD. Interestingly, the imaging modalities performed, including fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (SD-OCT), clearly highlighted the presence of spontaneous RPE tears in the context of non-exudative AMD, while in general, RPE tears are a well-recognized complication of exudative AMD. Conclusions. - To our knowledge, this is the first description of spontaneous RPE tears as a possible complication of GA due to non-exudative AMD. (C) 2015 Elsevier Masson SAS. All rights reserved. OI Corvi, Federico/0000-0002-2661-5500Purpose. - To report two cases of spontaneous retinal pigment epithelial (RPE) tears occurring in two patients affected with geographic atrophy (GA) due to non-exudative age-related macular degeneration (AMD). Case report. - Two patients (a 79-year-old man and a 71-year-old woman) presented to our department with progressive visual loss. The man had a best-corrected visual acuity (BCVA) of 20/100 in the right eye (RE) and 20/50 in the left eye (LE); the woman had a BCVA of 20/200 in the RE and 20/160 in the LE. Upon complete ophthalmologic examination, revealing a large area of atrophy (> 175 mu m in diameter) along with pigmentary changes, calcified drusen and no choroidal neovascularization (CNV) in either eye, the patients were diagnosed with GA due to non-exudative AMD. Interestingly, the imaging modalities performed, including fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (SD-OCT), clearly highlighted the presence of spontaneous RPE tears in the context of non-exudative AMD, while in general, RPE tears are a well-recognized complication of exudative AMD. Conclusions. - To our knowledge, this is the first description of spontaneous RPE tears as a possible complication of GA due to non-exudative AMD. (C) 2015 Elsevier Masson SAS. All rights reserved
Static characteristics and dynamic functionality of retinal vessels in longer eyes with or without pathologic myopia
No full textPurpose To analyze major retinal vessels in eyes with high myopia by means of the Dynamic Vessel Analyzer (DVA) in order to gather insight on retinal vascular functionality and better understand why these eyes are resistant to diabetes-related changes. Methods A total of 20 high-myopia eyes with pathologic myopia, 20 high-myopia eyes without pathologic myopia and 20 age- and sex-matched control subjects (without pathologic myopia) were included and compared. Results Dynamic analysis showed mean arterial dilation of 2.44 +/- 1.59 % in high-myopia eyes with pathologic myopia, 2.67 +/- 1.17 in high-myopia without pathologic myopia eyes, and 3.28 +/- 1.46 % in healthy eyes. Mean venous dilation was 3.45 +/- 1.82 %, 3.57 +/- 1.72, and 4.45 +/- 2.72 % respectively. Static analysis in high myopia eyes with pathologic myopia showed a mean central retinal artery equivalent (CRAE) of 171.6 +/- 24.3, a mean central retinal vein equivalent (CRVE) of 199.5 +/- 27.73, and a mean arteriovenous ratio (AVR) of 0.86 +/- 0.01. In patients with high myopia without pathologic myopia, we found a mean CRAE of 173 +/- 21.6, a mean CRVE of 198.2 +/- 18.8, and a mean AVR of 0.87 +/- 0.1. In control subjects, mean CRAE was 190.3 +/- 11.93, mean was CRVE 215.7 +/- 13.30, and mean AVR was 0.88 +/- 0.04. Conclusions Static and dynamic tests revealed that in high-myopia eyes, the vessels at the retinal posterior pole have reduced diameter, but are functionally comparable to control subjects. This supports the hypothesis of reduced oxygen consumption in high-myopia eyes. OI Corvi, Federico/0000-0002-2661-5500Purpose To analyze major retinal vessels in eyes with high myopia by means of the Dynamic Vessel Analyzer (DVA) in order to gather insight on retinal vascular functionality and better understand why these eyes are resistant to diabetes-related changes. Methods A total of 20 high-myopia eyes with pathologic myopia, 20 high-myopia eyes without pathologic myopia and 20 age- and sex-matched control subjects (without pathologic myopia) were included and compared. Results Dynamic analysis showed mean arterial dilation of 2.44 +/- 1.59 % in high-myopia eyes with pathologic myopia, 2.67 +/- 1.17 in high-myopia without pathologic myopia eyes, and 3.28 +/- 1.46 % in healthy eyes. Mean venous dilation was 3.45 +/- 1.82 %, 3.57 +/- 1.72, and 4.45 +/- 2.72 % respectively. Static analysis in high myopia eyes with pathologic myopia showed a mean central retinal artery equivalent (CRAE) of 171.6 +/- 24.3, a mean central retinal vein equivalent (CRVE) of 199.5 +/- 27.73, and a mean arteriovenous ratio (AVR) of 0.86 +/- 0.01. In patients with high myopia without pathologic myopia, we found a mean CRAE of 173 +/- 21.6, a mean CRVE of 198.2 +/- 18.8, and a mean AVR of 0.87 +/- 0.1. In control subjects, mean CRAE was 190.3 +/- 11.93, mean was CRVE 215.7 +/- 13.30, and mean AVR was 0.88 +/- 0.04. Conclusions Static and dynamic tests revealed that in high-myopia eyes, the vessels at the retinal posterior pole have reduced diameter, but are functionally comparable to control subjects. This supports the hypothesis of reduced oxygen consumption in high-myopia eyes
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
