1,721,071 research outputs found
Risk stratification in secondary cardiovascular prevention
No full textWorldwide, more than 7 million people experience acute myocardial infarction (AMI) every year (1), and although substantial reduction in mortality has been obtained in recent decades, one-year mortality rates are still in the range of 10%. Among patients who survive AMI, 20% suffer a second cardiovascular event in the first year and approximately 50% of major coronary events occur in those with a previous hospital discharge diagnosis of AMI (2). Despite the evidence that lifestyle changes and risk factors management strongly improve long-term prognosis, preventive care post-AMI remains sub-optimal. Cross-sectional data from the serially conducted EUROASPIRE surveys in patients with established ischemic heart disease (IHD) and people at high cardiovascular risk have demonstrated a high prevalence of unhealthy lifestyle, modifiable risk factors and inadequate use of drug therapies to achieve blood pressure and lipid goals (3). Secondary prevention programmes, defined as the level of preventive care focusing on early risk stratification, are highly recommended in all IHD patients, to restore quality of life, maintain or improve functional capacity and prevent recurrence
INFLUENCE OF INTRA-CORONARY ENHANCEMENT ON DIAGNOSTIC ACCURACY WITH 64-SLICE CT CORONARY ANGIOGRAPHY
No full textAbstract We assessed the effect of
intra-coronary attenuation on diagnostic
accuracy using 64-slice
computed tomography coronary
angiography (CT-CA). We enrolled
170 patients with suspected coronary
artery disease who underwent conventional
coronary angiography (CA)
and 64-slice CT-CA (100 ml of
Iomeprol 400 mg I/ml at 4 ml/s). The
study population was divided into two
groups (85 patients each based on
median attenuation of 326 HU) based
on mean arterial attenuation; group 1
with low attenuation and group 2 with
high attenuation. Diagnostic accuracy
for the detection of significant coronary
artery stenosis was determined
for both groups using CA as reference
standard. Overall, 163 significant stenoses
were detected in 1,030 assessable
coronary artery segments in
group 1 compared with 160 significant
stenoses in 1,020 assessable segments
in group 2. The average intra-coronary
attenuation was significantly (P<
0.05) higher for group 2 (388±46 HU)
compared with group 1 (291±33 HU).
The corresponding sensitivity and
specificity values for detection of
significant coronary artery stenosis
were higher for group 2 (96.3% and
97.6%, respectively) than for group 1
(82.8% and 93.2%, respectively) and
were more marked in distal coronary
segments than in proximal segments.
Higher intra-coronary attenuation on
CT-CA results in greater diagnostic
accuracy for detection of coronary
artery stenosis.
Prediction of cardiovascular events using risk scores or electrocardiogram: A farewell to arms
No full text
[Groups with volunteers cardiac surgery patients: experience in a cardiovascular rehabilitation department].
No full textAlterato riempimento ventricolare sinistro in soggetti sani insulino resistenti
No full textItalian Heart Journa
Autologous heterotopic transplant of the thyroid in man: functional and clinical study after twenty-four years
No full textEffects of "Central Hypervolemia" by water immersion on renin -aldosterone system and ACTH-cortisol axis in haemodialyzed patients
No full textWater immersion up to the neck (WI) results in a central hypervolemia; the increased atrial pressure, evoked by this maneuver, stimulates low pressure receptors (LPR) which exert tonic inhibition on sympathetic activity and suppresses both the renin (PRA)-aldosterone (PA) system and the ACTH-cortisol axis in normal man. In hemodialyzed patients (HP), in whom autonomic neuropathy has been frequently found, PRA and ACTH were not suppressed during WI while plasma cortisol and PA were reduced. Other modulators, like dopamine, are supposed to be involved in regulating cortisol and PA levels in HP
[Paraneoplastic polymyalgia rheumatica. Case contribution].
No full textPolymyalgia rheumatica (PMR) is an inflammatory disease which mainly affects the elderly and is highly responsive to steroid therapy. PMR can be associated with giant cell arteritis as well as with malignancy. Three cases of malignant neoplasms of the digestive apparatus beginning with a clinical picture similar to that of the "idiopathic" PMR, but with poor response to steroid therapy are presented. In one case the primary neoplasm was found only at the autopsy. These observations suggest that a careful clinical evaluation and a long follow-up are necessary for a correct diagnosis of "idiopathic" PMR
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