5,758 research outputs found

    Synergy and Group Size in Microbial Cooperation

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    Microbes produce many molecules that are important for their growth and development, and the exploitation of these secretions by nonproducers has recently become an important paradigm in microbial social evolution. Although the production of these public-goods molecules has been studied intensely, little is known of how the benefits accrued and the costs incurred depend on the quantity of public-goods molecules produced. We focus here on the relationship between the shape of the benefit curve and cellular density, using a model assuming three types of benefit functions: diminishing, accelerating, and sigmoidal (accelerating and then diminishing). We classify the latter two as being synergistic and argue that sigmoidal curves are common in microbial systems. Synergistic benefit curves interact with group sizes to give very different expected evolutionary dynamics. In particular, we show that whether and to what extent microbes evolve to produce public goods depends strongly on group size. We show that synergy can create an "evolutionary trap" that can stymie the establishment and maintenance of cooperation. By allowing density-dependent regulation of production (quorum sensing), we show how this trap may be avoided. We discuss the implications of our results on experimental design.</p

    Report on Meteorological Research March 1, 1935 (m-1)

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    The object of the report was to elucidate in detail the various features of the research program in meteorology being carried on at the Daniel Guggenheim Airship Institute in Akron, Ohio. Mr. L. J. Fangman, of the U.S. Weather Bureau, was collaborating with the author in carrying out work such as a study of autographic records of the various meteorological elements during frontal passages with a view to the possible prediction of the intensity of the accompanying disturbance as it may affect the operation of aircraft and a study of atmospheric gustiness with a view to finding the dependence between frequency end amplitude of velocity fluctuations and the vertical temperature and velocity gradients

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    Defoe's Foes:The Author as Character

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    The most famous fictional Defoe features in J. M. Coetzee’s Foe (1986), in which he conjures Robinson Crusoe out of a memoir by a “true” castaway. Harrumphing across the country alongside the modern-day narrator of Stuart Campbell’s Daniel Defoe’s Railway Journey (2017), a surreal iteration quite literally leaps out of the pages of a Penguin Classics edition of his real-life counterpart’s travel writing. Setting aside a long tradition of neo-Georgian novels in which Defoe cameos as a seventeenth-century spy, a Defoe-as-character only for all intents and purposes, this chapter attends to two complex cases in the genre of author fictions: Coetzee’s Foe and Campbell’s Defoe

    Erratic Flu Vaccination Emerges from Short-Sighted Behavior in Contact Networks

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    Daniel M. Cornforth is with UT Austin, Timothy C. Reluga is with Pennsylvania State University, Eunha Shim is with Yale University School of Medicine, Chris T. Bauch is with University of Guelph, Alison P. Galvani is with Yale University School of Medicine, Lauren Ancel Meyers is with UT Austin and the Santa Fe Institute.The effectiveness of seasonal influenza vaccination programs depends on individual-level compliance. Perceptions about risks associated with infection and vaccination can strongly influence vaccination decisions and thus the ultimate course of an epidemic. Here we investigate the interplay between contact patterns, influenza-related behavior, and disease dynamics by incorporating game theory into network models. When individuals make decisions based on past epidemics, we find that individuals with many contacts vaccinate, whereas individuals with few contacts do not. However, the threshold number of contacts above which to vaccinate is highly dependent on the overall network structure of the population and has the potential to oscillate more wildly than has been observed empirically. When we increase the number of prior seasons that individuals recall when making vaccination decisions, behavior and thus disease dynamics become less variable. For some networks, we also find that higher flu transmission rates may, counterintuitively, lead to lower (vaccine-mediated) disease prevalence. Our work demonstrates that rich and complex dynamics can result from the interaction between infectious diseases, human contact patterns, and behavior.This research was supported by NIH grant U01 GM087719, grants from the James F. McDonnell Foundation and Bill and Stephanie Sick to LAM, and the Bill and Melinda Gates Foundation grant 49276 to TCR. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Biological Sciences, School o

    Letter from Daniel K. Inouye, Senator, to Sharon M. Tanihara, September 21, 1990

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    Correspondence from Senator Daniel Inouye to Sharon Tanihara regarding the Civil Liberties Act of 1988 and Tanihara's eligibility for restitution payments.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications

    Letter from Daniel K. Inouye, Senator, to Sharon M. Tanihara, January 11, 1991

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    Correspondence from Senator Daniel Inouye to Sharon Tanihara regarding the Civil Liberties Act of 1988 and eligibility for restitution payments for non-Japanese spouses who chose to live in an incarceration camp with their Japanese American partners.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications

    Letter from Sharon M. Tanihara to Daniel Inouye, Senator, December 10, 1990

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    Correspondence from Sharon Tanihara to Senator Daniel Inouye regarding Tanihara's views on the Civil Liberties Act of 1988 and her opinions on restitution payments for individuals previously excluded from that bill.The Japanese American Archival Collection documents the people, places, and daily life of Japanese Americans, primarily those who lived in the once thriving community of pre-war Florin in the Sacramento region, as well as the conditions in American incarceration camps during World War II. The approximately 7,000 original items include personal and official letters, photographs, diaries, arts and crafts, newsletters, textiles, camps artifacts, yearbooks and other publications

    American Roulette: The Effect of Reminders of Death on Support for George W. Bush in the 2004 Presidential Election

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    An experiment was conducted to assess the effect of a subtle reminder of death on voting intentions for the 2004 U.S. presidential election. On the basis of terror management theory and previous research, we hypothesized that a mortality salience induction would increase support for President George W. Bush and decrease support for Senator John Kerry. In late September 2004, following a mortality salience or control induction, registered voters were asked which candidate they intended to vote for. In accord with predictions, Senator John Kerry received substantially more votes than George Bush in the control condition, but Bush was favored over Kerry following a reminder of death, suggesting that President Bush's re-election may have been facilitated by non conscious concerns about mortality in the aftermath of September 11, 2001.This is an electronic version of the article published in Analyses of Social Issues and Public Policy, 5(1):177-187, 2005 Dec.The definitive version is available at www3.interscience.wiley.co

    Author correction: obesity and ethnicity alter gene expression in skin

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    Daniel Butler was omitted from the author list in the original version of this Article. The Author contributions section now reads: “J.M.W. designed, conducted, and contributed to the writing of the manuscript, prepared Fig. 1. S.G. evaluated and did statistical analysis on the skin and fat samples, prepared Figs. 2–9. J.O.A. evaluated and contributed to writing the manuscript. D.B prepared and sequenced DNA libraries for the skin microbiota data, and wrote the applicable parts of the methods section. C.M. analyzed and wrote up the skin microbiota data, prepared Fig. 10. All authors have read the manuscript and approved its contents. D.D. analyzed and wrote up the skin microbiota data. S.Z. ran and analyzed the skin metabolite data. J.S. assisted in design, analysis and wrote up the skin metabolite data. J.K. assisted in analysis write up of skin and fat data. J.L.B. assisted in analysis, interpretation and writing of the manuscript. P.R.H. designed, analyzed, interpreted the data, and was the primary author of the manuscript.” This has been corrected in the PDF and HTML versions of the Article, and in the accompanying Supplementary Information file.</p
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