313,105 research outputs found
Martha Dunn Corey personal correspondence
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Martha Dunn Corey legal documents
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Martha Dunn Corey professional correspondence
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Martha Dunn Corey and family photographs
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Travel, professional, and financial documents
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Pledge of love
No full textMartha Dunn Corey graduated from the Woman's Medical College of Pennsylvania in 1879. She became the first resident physician in La Jolla, California
Interview with Walter Corey by Andrea L’Hommedieu
No full textBiographical NoteWalter Ellsworth Corey III was born June 19, 1941, in White Plains, New York, to Walter E., Jr. and Theresa (Stallone) Corey and grew up mainly on Staten Island. His father was an insurance executive with Metropolitan Life and his mother was a homemaker. They divided their time between New York and Ogunquit, Maine. He attended Yale Law School, then moved to Maine to join the Portland law firm Bernstein Shur; he left the firm to serve in the Ken Curtis administration as Maine’s first federal coordinator. He was active in several of Mitchell’s campaigns, for governor and for the U.S. Senate, and they shared a fondness for tennis.
SummaryInterview includes discussion of: family and educational background; Ken Curtis administration; working with George Mitchell on policy and speeches in the late 1960s; description of playing tennis with George Mitchell and foot faulting; 1974 Maine gubernatorial campaign; 1982 U.S. Senate campaign; sense of humor and tennis stories (Harold Pachios and Juris Ubans); and description of George Mitchell’s accomplishments and attributes
Silencing disease genes in the laboratory and the clinic
No full textSynthetic nucleic acids are commonly used laboratory tools for modulating gene expression and have the potential to be widely used in the clinic. Progress towards nucleic acid drugs, however, has been slow and many challenges remain to be overcome before their full impact on patient care can be understood. Antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) are the two most widely used strategies for silencing gene expression. We first describe these two approaches and contrast their relative strengths and weaknesses for laboratory applications. We then review the choices faced during development of clinical candidates and the current state of clinical trials. Attitudes towards clinical development of nucleic acid silencing strategies have repeatedly swung from optimism to depression during the past 20 years. Our goal is to provide the information needed to design robust studies with oligonucleotides, making use of the strengths of each oligonucleotide technology
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
