87,166 research outputs found
Analisi dell'efficacia di alternativi modelli di finanziamento degli ospedali: studio di un caso
No full textAnalisi della domanda di salute espressa dalla popolazione straniera irregolare in una regione italiana
No full textAnalisi dell'efficacia di alternativi modelli di finanziamento degli ospedali: studio di un caso
No full textAnalisi della domanda di salute espressa dalla popolazione straniera irregolare in una regione italiana
No full textPacchetti di prestazioni alternative al ricovero ordinario: una proposta di tariffazione
No full textEEG spectral profile to stage Alzheimer's disease
No full textObjective: The present study was undertaken to investigate whether a synoptic parameter of quantitative EEG (qEEG), such as the power spectral profile, may be used as a simple marker to stage Alzheimer's disease (AD) in the clinical setting. Methods: To this purpose, the qEEG spectral profile was examined in 48 patients (mean age: 73 years) with probable (NINCDS-ADRDA criteria) AD, who were divided into 4 groups, according to the Global Deterioration Scale (GDS; score: 3-6). The spectral profile of each patient was expressed by the relative power of seven frequency bands (2-3.5, 4-5.5, 6-7.5, 8-9.5, 10-11.5, 12-13.5, 14-22.5 Hz). Mean values in each of the four GDS groups as well as in a control group of 18 healthy elderly subjects underwent multivariate analysis of variance. Results: A normally shaped but shifted-to-the left spectral profile was found in GDS 3 group, whereas a reduced background rhythm with various increase in slow activity power characterized both GDS 4 and 5 groups. Finally, an 'exponential asymptotic' profile with the highest power in the lowest frequencies was the hallmark of GDS 6 group. Overall, the 4-5.5 Hz and the 10-11.5 Hz band powers showed the highest statistical significance in differentiating the patient groups between one another and from controls (P < 0.0001). Conclusions: These data show that spectral profile is a very simple parameter which can be used to stage the disease on a pathophysiological basis
Fernando Copello, Marina Letourneur y Lucie Valverde (comps.), 3 poetas 3. Ensayos sobre la infancia en la obra de Juan Gelman, Alejandra Pizarnik y María Elena Walsh. Buenos Aires, Dedalus, 2020, 122 páginas
No full textRevisión del libro 3 poetas 3. Ensayos sobre la infancia en la obra de Juan Gelman, Alejandra Pizarnik y María Elena Walsh por F. Copello, M. Letourneur y L. Valverde (comps.)Revisión del libro 3 poetas 3. Ensayos sobre la infancia en la obra de Juan Gelman, Alejandra Pizarnik y María Elena Walsh por F. Copello, M. Letourneur y L. Valverde (comps.)
A pilot study to assess the feasibility and impact of a brief motivational intervention on problem drug and alcohol use in adult mental health inpatient units : study protocol for a randomized controlled trial
No full textBackground:
Substance misuse in those with severe mental health problems is common and associated with poor engagement in treatment and treatment outcomes. Up to 44% of those admitted into psychiatric inpatient facilities have coexisting substance-misuse problems. However, this is not routinely addressed as part of their treatment plan. A mental health admission may present a window of opportunity for inpatients to reevaluate the impact of their substance use. This study will aim to evaluate the effectiveness of a targeted brief motivational intervention in improving engagement in treatment and to assess how feasible and acceptable this intervention is to inpatients and staff as a routine intervention.
Methods/Design:
This randomized controlled trial will use concealed randomization; blind, independent assessment of outcome at 3 months; characterization of refusers and dropouts; and be analyzed according to the intention-to-treat principle. After baseline assessments, eligible participants will be randomized either to the Brief Integrated Motivational Intervention plus Treatment As Usual, or Treatment as Usual alone. Eligible participants will be those who are new admissions; >18 years; ICD-10 diagnosis of -schizophrenia or related disorder, bipolar affective disorder, recurrent depressive disorder, and DSM-IV diagnosis of substance abuse or dependence over the last 3 months. The primary outcome is engagement in treatment for substance misuse, and secondary outcomes include readiness to change substance misuse together with a cost-effectiveness analysis. Qualitative interviews with staff and participants will assess the acceptability of the intervention.
Discussion:
This pilot randomized trial will provide the first robust evidence base for inpatient care of people with severe mental health problems and co-morbid substance misuse and provide the groundwork for confirmatory trials to evaluate a potentially feasible, cost-effective, and easy-to-implement treatment option that may be readily integrated into standard inpatient and community-based care
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