6,110 research outputs found

    Overuse tendinosis, not tendinitis part 2: applying the new approach to patellar tendinopathy.

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    Patellar tendinopathy causes substantial morbidity in both professional and recreational athletes. The condition is most common in athletes of jumping sports such as basketball and volleyball, but it also occurs in soccer, track, and tennis athletes. The disorder arises most often from collagen breakdown rather than inflammation, a tendinosis rather than a tendinitis. Physicians must address the degenerative pathology underlying patellar tendinopathy because regimens that seek to minimize (nonexistent) inflammation would appear illogical. Suggestions for applying the 'tendinosis paradigm' to patellar tendinopathy management include conservative measures such as load reduction, strengthening exercises, and massage. Surgery should be considered only after a long-term and appropriate conservative regimen has failed

    The mitochondrial component of intracrine action

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    Re RN, Cook JL. The mitochondrial component of intracrin

    Solutions of the relativistic two-body problem II quantum mechanics

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    This second paper of a series discusses the formulation of the quantum mechanical equivalent of the relative time classical theory put forward in Part 1. The relativistic wave function is derived and a covariant addition theorem put forward which allows a covariant scattering theory to be established. The free particle eigenfunctions are not plane waves and a covariant partial wave analysis is given. A means is given by which wave functions which yield probability densities in 4-space can be converted to ones yielding the equivalent 3-space density. Bound states are considered and covariant analogues are given of the harmonic oscillator potential, Coulomb potential, the square well potential, and two-body fermion interactions. RESEARCH ARTICLE Previous Next Contents Vol 25 (2) Solutions of the Relativistic Two-Body Problem. II. Quantum Mechanics JL Cook Australian Journal of Physics 25(2) 141 - 166 Published: 1972 Abstract This paper discusses the formulation of a quantum mechanical equivalent of the relative time classical theory proposed in Part I. The relativistic wavefunction is derived and a covariant addition theorem is put forward which allows a covariant scattering theory to be established. The free particle eigenfunctions that are given are found not to be plane waves. A covariant partial wave analysis is also given. A means is described of converting wavefunctions that yield probability densities in 4-space to ones that yield the 3-space equivalents. Bound states are considered and covariant analogues of the Coulomb potential, harmonic oscillator potential, inverse cube law of force, square well potential, and two-body fermion interactions are discussed.https://doi.org/10.1071/PH72014

    Studies of surgical outcome after patellar tendinopathy: clinical significance of methodological deficiencies and guidelines for future studies. Victorian Institute of Sport Tendon Study Group.

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    Patellar tendinopathy is often treated surgically after failure of conservative treatment but clinical experience suggests that results are not uniformly excellent. The aim of this review was to (i) identify the different surgical techniques that have been reported and compare their success rates, and (ii) critically assess the methodology of studies that have reported surgical outcomes. Twenty-three papers and two abstracts were included in the review. Surgical procedures were categorized and outcomes summarized. Using ten criteria, an overall methodology score was derived for each paper. Criteria for which scores were generally low (indicating methodological deficiency) concerned the type of study, subject selection process and outcome measures. We found a negative correlation between papers' reported success rates and overall methodology scores (r= -0.57, P<0.01). There was a positive correlation between year of publication and overall methodology score (r=0.68, P<0.001). We conclude that study methodology may influence reported surgical outcome. We suggest practical guidelines for improving study design in this area of clinical research, as improved study design would provide clinicians with a more rigorous evidence-base for treating patients who have recalcitrant patellar tendinopathy

    Diel rhythm and thermal independence of metabolic rate in a benthic shark

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    &lt;p&gt;Data presented in:&lt;br /&gt;Wheeler CR, Kneebone J, Heinrich D, Strugnell JM, Mandelman JW, Rummer JL. 2022. Diel rhythm and thermal independence of metabolic rate in a benthic shark (Journal of Biological Rhythms)&lt;/p&gt; &lt;p&gt;Data collected from adult epaulette sharks (H. ocellatum) at JCU MARFU from July 2020-2021. Ethical approval for this study was received from JCU under ethics approval A2655. The full methodology is available in the Open Access publication from the Related publications link below.&lt;/p&gt; &lt;p&gt;This dataset contributes to a PhD dissertation by Carolyn Wheeler from James Cook University and The University of Massachussetts Boston.&lt;/p&gt; &lt;p&gt;Software/equipment used to create/collect the data: OXROB3 fibre optic probe with a Firesting Optical Oxygen Meter (Pyroscience GmbH, Aachen, Germany).&lt;br /&gt;Software/equipment used to manipulate/analyse the data: R studio&lt;/p&gt

    Reflections of a Jewish, Lesbian Author

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    In this essay, Jewish lesbian author Leslea Newman speaks of the importance of finding one's own identity reflected in works of literature, citing examples of her own work, and recommending the writings of other Jewish lesbian authors of merit

    The challenges faced in the design, conduct and analysis of surgical randomised controlled trials

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    Randomised evaluations of surgical interventions are rare; some interventions have been widely adopted without rigorous evaluation. Unlike other medical areas, the randomised controlled trial (RCT) design has not become the default study design for the evaluation of surgical interventions. Surgical trials are difficult to successfully undertake and pose particular practical and methodological challenges. However, RCTs have played a role in the assessment of surgical innovations and there is scope and need for greater use. This article will consider the design, conduct and analysis of an RCT of a surgical intervention. The issues will be reviewed under three headings: the timing of the evaluation, defining the research question and trial design issues. Recommendations on the conduct of future surgical RCTs are made. Collaboration between research and surgical communities is needed to address the distinct issues raised by the assessmentof surgical interventions and enable the conduct of appropriate and well-designed trials.The Health Services Research Unit is funded by the Scottish Government Health DirectoratesPeer reviewedPublisher PD
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