1,720,995 research outputs found
Modelling fast forms of visual neural plasticity using a modified second-order motion energy model
No full textThe Adelson-Bergen motion energy sensor is well established as the leading model of low-level visual motion sensing in human vision. However, the standard model cannot predict adaptation effects in motion perception. A previous paper Pavan et al.(Journal of Vision 10:1–17, 2013) presented an extension to the model which uses a first-order RC gain-control circuit (leaky integrator) to implement adaptation effects which can span many seconds, and showed that the extended model’s output is consistent with psychophysical data on the classic motion after-effect. Recent psychophysical research has reported adaptation over much shorter time periods, spanning just a few hundred milliseconds. The present paper further extends the sensor model to implement rapid adaptation, by adding a second-order RC circuit which causes the sensor to require a finite amount of time to react to a sudden change in stimulation. The output of the new sensor accounts accurately for psychophysical data on rapid forms of facilitation (rapid visual motion priming, rVMP) and suppression (rapid motion after-effect, rMAE). Changes in natural scene content occur over multiple time scales, and multi-stage leaky integrators of the kind proposed here offer a computational scheme for modelling adaptation over multiple time scales
Quantitative material characterization based on the spectral decomposition of X-ray tomographic images
No full textA single-energy CT provides a map of gray levels simply related to X-rays linear attenuation coefficients, which could be very similar for different materials at a given energy. Images acquired at multiple energies allows for a quantitative description of an object. In this work, phantom images were acquired using synchrotron radiation CT at precisely defined energies. A successful attempt was made to differentiate the phantom materials with respect to their decomposition into basis materials
Sparks fade with distance: The effect of electric field distribution on global motion perception using different tES techniques
No full textPrevious evidence has shown that high-frequency transcranial random noise stimulation (hf-tRNS) reduces motion coherence thresholds when applied with a cephalic montage (i.e., return electrode over Cz). Extracephalic montages, which avoid stimulating regions under the return electrode, have also been used to modulate behavioral performance. In this study, we investigated the effects of different transcranial electrical stimulation (tES) protocols on visual motion discrimination, placing the return electrode on the ipsilateral arm. We assessed the impact of electrode positioning using hf-tRNS, anodal, cathodal transcranial direct current stimulation (tDCS), and Sham stimulation over hMT+, a brain region involved in global motion perception. Motion direction discrimination was measured using random dot kinematograms (RDKs). Given the increased distance between the stimulation and return electrodes in this montage, we expected a smaller reduction in motion discrimination thresholds compared to our previous study. Our results suggest that increasing interelectrode distance alters current flow characteristics-such as current distribution and focality-within the cortical areas under the target electrode, producing different effects. Additionally, no significant effects were observed with the other tES protocols tested. Our findings suggest that change in the interelectrode distance influences current flow characteristics, such as current distribution and focality, within the cortical areas under the target electrode, resulting in differential neuromodulatory effects. These results highlight the importance of stimulation configuration on performance, particularly a potential electric field shift due to the change in the interelectrode distance. Given the widespread application of brain stimulation techniques in clinical and cognitive research, our results can guide future studies carefully considering this further aspect of stimulation montage configurations. (c) 2025 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract ID: 176 Geant4 implementation of inter-atomic interference effect in small-angle coherent X-ray scattering for materials of medical interest
No full textAdvanced applications of digital mammography such as dual-energy and tomosynthesis require multiple exposures and thus deliver higher dose compared to standard mammograms. A straightforward manner to reduce patient dose without affecting image quality would be removal of the anti-scatter grid, provided that the involved reconstruction algorithms are able to take the scatter figure into account [1]. Monte Carlo simulations are very well suited for the calculation of X-ray scatter distribution and can be used to integrate such information within the reconstruction software. Geant4 is an open source C++ particle tracking code widely used in several physical fields, including medical physics [2,3]. However, the coherent scattering cross section used by the standard Geant4 code does not take into account the influence of molecular interference. According to the independent atomic scattering approximation (the so-called free-atom model), coherent radiation is indistinguishable from primary radiation because its angular distribution is peaked in the forward direction. Since interference effects occur between x-rays scattered by neighbouring atoms in matter, it was shown experimentally that the scatter distribution is affected by the molecular structure of the target, even in amorphous materials. The most important consequence is that the coherent scatter distribution is not peaked in the forward direction, and the position of the maximum is strongly material-dependent [4]. In this contribution, we present the implementation of a method to take into account inter-atomic interference in small-angle coherent scattering in Geant4, including a dedicated data set of suitable molecular form factor values for several materials of clinical interest. Furthermore, we present scatter images of simple geometric phantoms in which the Rayleigh contribution is rigorously evaluated
Improvement in visual perception after high-frequency transcranial random noise stimulation (hf-tRNS) in those with migraine: An equivalent noise approach
Full text linkMigraine is a common neurological disorder with strong links to vision. Interictal migraine is thought to be characterised by internal noise in the brain, possibly due to increased variability in neural firing, which can be estimated using equivalent noise tasks. High-frequency transcranial random noise stimulation (hf-tRNS) can be used to modulate levels of internal noise in the brain, and so presents a possible therapy to redress noise levels in the migraine brain. This is a case-control study using a 2-alternative forced choice (2AFC) design. Hf-tRNS and Sham control stimulation were used alongside a global motion direction discrimination task and visually based equivalent noise tasks. The migraine group demonstrated increased baseline internal noise levels compared to the control group. Internal noise levels, and sampling, were reduced using hf-tRNS but not Sham stimulation. However, there were no differences in terms of coherence thresholds, slopes, and lapse rate for global motion discrimination between the two groups. This is the first demonstration of the possibility of decreasing internal noise levels in migraine using hf-tRNS. Future work could explore the possibility of neurostimulation as a therapy for migraine
Tilt aftereffect following adaptation to translational Glass patterns
Full text linkGlass patterns (GPS) consist of randomly distributed dot pairs (dipoles) whose orientations are determined by specific geometric transforms. We assessed whether adaptation to stationary oriented translational GPS suppresses the activity of orientation selective detectors producing a tilt aftereffect (TAE). The results showed that adaptation to GPS produces a TAE similar to that reported in previous studies, though reduced in amplitude. This suggests the involvement of orientation selective mechanisms. We also measured the interocular transfer (IOT) of the GP-induced TAE and found an almost complete IOT, indicating the involvement of orientation selective and binocularly driven units. In additional experiments, we assessed the role of attention in TAE from GPS. The results showed that distraction during adaptation similarly modulates the TAE after adapting to both GPS and gratings. Moreover, in the case of GPS, distraction is likely to interfere with the adaptation process rather than with the spatial summation of local dipoles. We conclude that TAE from GPS possibly relies on visual processing levels in which the global orientation of GPS has been encoded by neurons that are mostly binocularly driven, orientation selective and whose adaptation-related neural activity is strongly modulated by attention
The effects of high-frequency transcranial random noise stimulation (hf-tRNS) on global motion processing: An equivalent noise approach
No full textBackground: High frequency transcranial random noise stimulation (hf-tRNS) facilitates performance in several perceptual and cognitive tasks, however, little is known about the underlying modulatory mechanisms. Objective: In this study we compared the effects of hf-tRNS to those of anodal and cathodal tDCS in a global motion direction discrimination task. An equivalent noise (EN) paradigm was used to assess how hf-tRNS modulates the mechanisms underlying local and global motion processing. Method: Motion coherence threshold and slope of the psychometric function were estimated using an 8AFC task in which observers had to discriminate the motion direction of a random dot kinematogram presented either in the left or right visual hemi-field. During the task hf-tRNS, anodal and cathodal tDCS were delivered over the left hMT + . In a subsequent experiment we implemented an EN paradigm in order to investigate the effects of hf-tRNS on the mechanisms involved in visual motion integration (i.e., internal noise and sampling). Results: hf-tRNS reduced the motion coherence threshold but did not affect the slope of the psychometric function, suggesting no modulation of stimulus discriminability. Anodal and cathodal tDCS did not produce any modulatory effects. EN analysis in the last experiment found that hf-tRNS modulates sampling but not internal noise, suggesting that hf-tRNS modulates the integration of local motion cues. Conclusion: hf-tRNS interacts with the output neurons tuned to directions near to the directional signal, incrementing the signal-to-noise ratio and the pooling of local motion cues and thus increasing the sensitivity for global moving stimuli
Limited Attention Diminishes Spatial Suppression From Large Field Glass Patterns
No full textGlass patterns (GPs) consist of randomly distributed dot pairs (dipoles) whose orientations are determined by specific geometric transforms. We investigated the role of visuospatial attention in the processing of global form from GPs by measuring the effect of distraction on adaptation to GPs. In the nondistracted condition, observers were adapted to coherent GPs. After the adaptation period, they were presented with a test GP divided in two halves along the vertical and were required to judge which side of the test GP was more coherent. In the attention-distracted condition, a high-load rapid serial visual presentation task was performed during the adapting period. The magnitude of the form after-effect was measured using a technique that measures the coherence level at which the test GP appears random. The rationale was that if attention has a modulatory effect on the spatial summation of dipoles, in the attention-distracted condition, we should expect a weaker form after-effect. However, the results showed stronger form after-effect in the attention-distracted condition than in the nondistracted condition, suggesting that distraction during adaptation increases the strength of form adaptation. Additional experiments suggested that distraction may reduce the spatial suppression from large-scale textures, strengthening the spatial summation of local-oriented signals
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
