1,720,975 research outputs found

    Antiviral treatment options for covid-19 by reduction of viral load and viral shedding

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    The coronavirus disease 2019 (COVID-19) virus is a public health emergency of international concern, without known effective pharmaceutical treatment so far. It is difficult to treat infected patients who are experiencing acute respiratory failure, liver or cardiac injury, gastroenteritis and many other complications without any drug recommendation. Reducing the viral load is the most important key for Covid-19 treatment, where complication due to infection is highly correlated with the number of viral particles present in the lung and other organs of the patient. Most antivirals are effective against a wide range of viruses, where they inhibit viral development. Some of the possible antiviral treatment options for COVID-19 could be discovered from flu viral treatment that had led to quick respiratory illness recovery through reduction of viral load and viral shedding

    Zinc supplementation for respiratory illness and acute gastroenteritis as complement treatment for covid-19

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    An outbreak of atypical pneumonia by the novel coronavirus disease 2019 (COVID-19), has been reported in Wuhan, China since December, 2019. It is a severe respiratory illness with many other symptoms such as gastroenteritis. Clinical trials has proved that Zn is a promising supplement that can ease of cough, fever and vomiting, dysentery, respiratory illness, diarrhea duration and recovery, duration of hospitalization and morbidity. This article suggests a potential role, which should be considered in the clinical management, and safeness for Zn supplementation for respiratory illness and acute gastroenteritis as compliment treatment for covid-19

    Risk factors of covid 19 transmission in cholera endemic countries

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    COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing deaths, illnesses and economic despair. The least developed countries have limited or lack of medicine, ventilators, beds, water electricity, availability of doctors’ service for a large population and facing challenges to handle the economic fallout of the crisis. Cholera patients are more likely to reside in a slum, and this triggers worries with higher infection and spread chances if they were to be contracted with coronavirus. Decrease maternal education and reduce family income could increase cholera risk in rural children. Low Socioeconomic status, clean water supply and limited healthcare facilities may pose risks of covid spread. Should an awareness and knowledge of covid 19 in cholera endemic setting is developed, it is the residents of poor nation that stand to benefit the most

    Treatment of gastroenteritis in covid-19 children

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    SARS-CoV-2 is highly contagious and has resulted in a rapid pandemic of COVID-19 that posing a threat to public health. They are causing a severe acute respiratory syndrome and known to infect the neurological, enteric, and hepatic systems. The aim of this document is to provide recommendations for a systematic approach for the gastroenteritis treatment in COVID-19 children where most important treatment options where discussed

    The poorly understood yet potent risk of pulmonary artery thrombosis in-situ in Post-Acute COVID-19 syndrome

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    Abstract Pulmonary artery thrombosis in-situ is a term used to describe a pulmonary embolism occurs in the absence of deep vein thrombosis in the lower extremities. Most cases occur in a patient who had a recent traumatic injury to the chest. Other risk factors include the presence of hypercoagulable conditions, including inflammatory state, hypoxia and vascular endothelial injury. Although it has been discussed extensively in the acute COVID-19 disease, pulmonary artery thrombosis in-situ that occur in the setting of Post-Acute COVID-19 syndrome is not commonly reported and poorly understood

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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