143,976 research outputs found
Muerte s\ufabita en cardiopat\ueda cong\ue9nita
Ia muerte cardiaca s\ufabita es un mecanismo frecuente de defunci\uf3n relacionado con anormalidades cardiacas cong\ue9nitas. Los diversos mecanismos comprenden la falta de la circulaci\uf3n transicional, erritmias. complicaciones posoperatorias y perioperatorias en el neonato. y la isquemia coronaria, arritmias, sepsis, trombosis o crisis hipertensiva pulmonar en el ni\uf1o mayor. El conocimiento (le la evoluci\uf3n natural de las formas tratadas quir\ufargicamente y (le las formas no operadas de c:udiopal\ueda cong\ue9nita y la vigilancia s largo plazo con la detecci\uf3n y tralntnicnto de las anormalidades hemodin\uedutticts suby:tcenies deben mejorar los resultados. llay uno, cuantos pacientes con anomal\uedas cw(liacas cong\ue9nitas que son curados, y la mayor\ueda requiere lratamici\ufao a largo plazo
Giu COVID an toan cho nguoi lao dong doi hoi nhieu hon la chi tuan theo cac lenh y te cong cong
Cho den nay trong dai dich, loi khuyen ve suc khoe cong dong cua nha nuoc da tro thanh trung tam cua thong diep cong khai ve viec bao ve cong dong khoi su lay lan cua COVID-19. Nhung chi tuan theo cac lenh y te cong cong se khong nhat thiet phai dap ung cac nghia vu cua nguoi su dung lao dong de bao ve nhan vien khoi COVID, dac biet la khi cac han che de dang o cac bang mien Dong. Tat nhien, bao ve nhan vien khoi COVID la tot cho nhan vien va cung tot cho to chuc vi no se giam kha nang nhan vien bi om. Chi rieng viec tiem phong se khong dam bao mot noi lam viec an toan COVID. Ngay ca nhung nguoi duoc tiem phong hai lan cung co the bi nhiem benh. Tiem phong giam nguy co lay nhiem tu 60% (AstraZeneca) den 80% (Pfizer). Va nhung nguoi duoc tiem phong hai lan cung co the truyen vi rut, mac du mot lan nua voi ty le thap hon nhieu
Hierarchical Structure Formation of Cylindrical Brush Polymer-Surfactant Complexes
The complex formation of cylindrical brush polymers with poly(L-lysine) side chains (PLL) and sodium dodecyl sulfate (SDS) can induce a helical conformation of the cylindrical brush polymer in aqueous solution (Gunari, N.; Cong, Y.; Zhang, B.; Fischer, K.; Janshoff, A.; Schmidt, M. Macromol. Rapid Commun. 2008, 29, 821-825). Herein, we have systematically investigated the influence of surfactant, salt, and pH on the supramolecular structure formation. The cylindrical brush polymers and their complexes with surfactants were directly visualized by atomic force microscopy in air and in aqueous solution. The alkyl chain length (measured by the carbon number, n) of the surfactant plays a key role. While helical structures were formed with n = 10, 11, and 12, no helices were observed with n 13. Addition of salt destroys the helical structures as do pH conditions below 4 and above 6, most probably because the polymer-surfactant complexes start to disintegrate. Circular dichroism was utilized to monitor the PLL side chain conformation and clearly revealed that beta-sheet fort-nation of the side chains induces the helical conformation of the atactic main chain.German Science Foundation [SFB 625
BLEFAROFIMOSIS, PALADAR HENDIDO Y CARDIOPAT\ucdA CONG\uc9NITA ASOCIADA A D\uc9FICIT COGNITIVO, S\ucdNDROME DE BLEFAROFIMOSIS TIPO OHDO
El S\uedndrome Blefarofimosis tipo Ohdo est\ue1 constituido por m\ufaltiples malformaciones cong\ue9nitas, entre ellas; blefarofimosis, ptosis palpebral e hipoplasia dental, adem\ue1s de retardo en el crecimiento, discapacidad intelectual y auditiva. Se presenta el caso de una escolar femenina, de 11 a\uf1os que presenta dismorfias faciales entre las que destaca blefarofimosis y paladar hendido. Presenta, adem\ue1s, antecedentes de cardiopat\ueda cong\ue9nita y retardo global del desarrollo, de padres aparentemente sanos, los cuales niegan isonimia. Se discuten los hallazgos y se comparan las caracter\uedsticas de la paciente con respecto a la bibliograf\ueda. Se han descrito menos de 30 pacientes en todo el mundo, lo cual hace el diagnostico de este s\uedndrome un hallazgo interesante. La sospecha diagn\uf3stica en vida intrauterina o temprana es fundamental para disminuir repercusiones en la calidad y esperanza de vida de los pacientes, la importancia de hacer un diagn\uf3stico temprano conlleva oportunamente al asesoramiento gen\ue9tico y multidisciplinario pertinente.
Palabras clave: blefarofimosis, paladar hendido, discapacidad intelectual.
ABSTRACT
The Ohdo blepharophimosis syndrome is constituted by multiple congenital malformations, among them; Blepharophimosis, palpebral ptosis and dental hypoplasia, as well as retarded growth, intellectual and auditory disability. We present the case of an 11 - year - old schoolgirl with facial dysmorphia, including Blepharophimosis and Cleft Palate. It also presents antecedents of congenital heart disease and global developmental delay, of apparently healthy parents, who deny isonimia. The findings are discussed and the characteristics of the patient compared to the literature are compared. Fewer than 30 patients have been described worldwide, making the diagnosis of this syndrome an interesting finding. Diagnostic suspicion in intrauterine or early life is essential to reduce the impact on quality and life expectancy of patients, the importance of making an early diagnosis leads timely to relevant genetic and multidisciplinary advice.
Key words: blepharophimosis, cleft palate, intellectual disability. <br
Self-Assembled Morphologies and Percolation Probability of Mixed Carbon Fillers in the Diblock Copolymer Template: Hybrid Particle-Field Molecular Dynamics Simulation
The self-assembly of polymer composites of mixed carbon fillers including single-walled carbon nanotube (SWCNT) and carbon black nanoparticles (CB NPs) in diblock copolymer (BCP) template are investigated using hybrid particle-field molecular dynamics simulations in this work. Simulations show, in agreement with experiments, that composites of BCP template with SWCNT have lower percolation threshold than that of BCP template with CB NPs. Moreover, the ratio between SWCNT and CB NPs has a strong influence on the percolation threshold of composites. The results of percolation probability show that adding more SWCNT (compared with CB NPs) to the BCP template could decrease the percolation threshold. However, a synergistic effect of percolation of the mixed carbon fillers in BCP template has been found. In particular, a nonlinear relation following the Boltzman function has been found, and the lowest percolation threshold exists with the volume ratio 4:1 (SWCNT/CB NPs) compared with the volume ratios of 1:1, 2:1, and 8:1 (SWCNT/CB NPs). The mixed carbon fillers also affect the morphologies of the BCP template, and the calculated radius of gyration of BCP shows that, in a higher concentration of the mixed fillers, the stretching of BCP is stronger, which results in the deformation of BCP template
Dr. LUIS DAO LAMEH Y EL PRIMER REPORTE DE CHAGAS CONG\uc9NITO
Se describe brevemente los logros cient\uedficos del Dr. Luis Dao, resaltando el primer reporte mundial de transmisi\uf3n cong\ue9nita del Trypanosoma cruzi y de la enfermedad
de Chagas, ocurrido en el estado Gu\ue1rico, Venezuela.
ABSTRACT
Dr. LUIS DAO LAMEH FIRST REPORT OF CONGENITAL CHAGAS
It briefly describes the scientific achievements of Dr. Luis Dao, emphasizing the description of the first global report congenital transmission of Trypanosoma cruzi
and Chagas disease, occurred in Gu\ue1rico State, Venezuela
Frecuencia de sifilis cong\ue9nita en el hospital pedi\ue1trico Dr. Agustin Zubillaga. Barquisimeto Julio 2004 - Octubre 2005
La S\uedfilis cong\ue9nita se define como caso a todos los \uf3bitos y lactantes producto de madre con s\uedfilis no tratada o inadecuadamente tratada (sin penicilina o con ella en menos de 30 d\uedas antes del parto), independientemente de la cl\uednica o estado serologico del ni\uf1o. Objetivo: determinar la frecuencia de s\uedfilis cong\ue9nita en el Hospital Pedi\ue1trico Dr. Agust\uedn Zubillaga. Barquisimeto Julio 2004 - Octubre 2005, adem\ue1s de evaluar el m\ue9todo diagnostico, plan de estudio y terap\ue9utica utilizada. Metodolog\ueda: Se realiz\uf3 un estudio de tipo descriptivo de corte transversal; la poblaci\uf3n y muestra, qued\uf3 conformada por 12 pacientes, con diagnostico de s\uedfilis cong\ue9nita a los cuales se les aplic\uf3 el instrumento de recolecci\uf3n de datos. Resultados: el 75% de los casos pertenec\uedan al sexo masculino, el diagnostico de la enfermedad se realiz\uf3 en el 75% en menores de 15 d\uedas de edad; el 100% de los casos presento s\uedfilis cong\ue9nita precoz; el diagnostico de ingreso estuvo asociado a esta en un 58.33%; el 83.33% fueron sintom\ue1ticos, constituyendo las lesiones de piel el 47.36%. El VDRL se realiz\uf3 como prueba diagnostica en el 91.66%; el estudio radiol\uf3gico de huesos largos es el mas solicitado en el 91.66% de los casos; el protocolo de estudio se realiz\uf3 en el 83.3%, y solo en el 50% fue adecuado; anemia, la complicaci\uf3n mas frecuente, seguida de la periostitis-osteocondritis y neurosifilis; el tratamiento empleado fue la penicilina cristalina con un 100%. Conclusi\uf3n: La frecuencia de s\uedfilis cong\ue9nita fue de 12 casos, con predominio en el sexo masculino; adem\ue1s un porcentaje elevado present\uf3 sintomatolog\ueda cl\uednica caracter\uedstica, constituyendo las lesiones de piel, la m\ue1s frecuente. La evaluaci\uf3n no se realiza siguiendo el protocolo de estudio y el manejo terap\ue9utico empleado es adecuado
Spatially-localized time dependent solutions including turbulence and their interactions in 2D Kolmogorov flow
In 2D Kolmogorov flow in small aspect ratio domains, spatially-localized solutions such as kink, traveling or time-dependent kink-antikink pars coexist. However, the conservation of the flow rate in the y direction strongly restrict combination of localized solutions and their positioning. We find that by adding a homogeneous flow U y their positioning is controlled and each of localized solutions including a spatially-localized chaos is isolated. Numerical results suggest that these isolated solutions can be elements constructing a whole flow
Characteristics of overlap region in high-Reynolds number turbulent channel flow
Direct numerical simulation of the fully developed turbulent channel flows have been carried out at the Reynolds number based on the friction velocity and the channel half width, 2000, 4000 and 8000. A hybrid 10th order accurate finite difference scheme in the stream and spanwise directions, and a second-order scheme in the wall-normal direction is adapted as the spatial discretization method. We observed the plateau profiles in the indicator function corresponded to the von Karman constant. Furthermore, second peak of streamwise pre-multiplied spectra were appeared in the same wall normal height, 300 < y+ < 600, in case of Re = 4000. Nevertheless, the effects of the lager than the channel half height scale on the streamwise turbulent intensity are fixed contributions without dependence on Reynolds number. These results suggested that the new streamwise vortexes are formed between buffer layer and outer layer with increasing of Reynolds number
(Proc. XIX World's Poultry Cong. Vol.2,p618)Commercial production of local chickens in Taiwan
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