44 research outputs found
Il riconoscimento giuridico del terzo sesso
No full textTaking inspiration from a recent ruling of the European Court of Human Rights, the Author investigates the condition of intersex people, questioning the possibility of legal recognition of a third sex within the Italian legal system. Given the only optional nature of health treatments aimed at conforming the anatomical aspect with the identity profile, as established by the most recent case law, the Author suggests the uselessness of gender indication, denying the constitutional protection of binary schematism
Sustainable methodologies for stability assessment of masonry vaulted structures
No full textThe analyses carried out on damaged masonry churches, after earthquakes that affected Italy
in recent years, highlighted that vaulted structures are among the most vulnerable elements. This paper
analyses a methodology for stability assessment of masonry vaults and domes, using non-invasive
methods to calculate their static equilibrium, without any destructive investigations. The survey is based
on a knowledge process, which provides the researchers with a series of information, from the historical
to the geometrical ones, accounting for peculiarities of each specific typology and related constructional
techniques
Safety and Efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A Prospective Randomized Clinical Trial
No full textIntroduction: Hemorrhoidal Disease (HD) is a very common anorectal disorder that affects millions of people around the world and represents a major medical and socioeconomic problem. The aim of the present study was to assess the safety and efficacy of Proctosoll Allevia® in patients affected by symptomatic HD in comparison with the results obtained from a control group.
Materials and methods: From January to February 2019, all the patients referred to the outpatient clinic of Rajalakshmi Hospital, who were complaining of first or second degree hemorrhoidal symptoms, were enrolled in the study. They were randomly assigned to either of the 2 arms. Group 1: patients were treated with the Proctosoll Allevia® and were under a controlled diet. Group 2: patients were only under a controlled diet without any treatment - control group.
Results: A total of 51 subjects were screened and 45 (13 F- 32 M) enrolled in the study. All the patients treated with topical application of the cream showed a statistically significant improvement of symptoms within 14 days from the beginning of the therapy if compared to patients who were treated only with a controlled diet. No major adverse events associated with the use of the new product were recorded.
Conclusion: The treatment of I-II degree symptomatic HD with Proctosoll Allevia® has demonstrated to be promising with a good profile of tolerability, safety and efficacy.
Keywords: Cortisone-free cream; Proctosoll Allevia®; hemorrhoidal prolapse; hemorrhoids; randomized clinical trial; safety and effica
Robot-assisted spleen preserving distal pancreatectomy: case report
No full textA 28-year-old female patient was incidentally diagnosed with a unilocular pancreatic cystic lesion
located in the body-tail of the pancreas. Findings at contrast-enhanced computed tomography scan and
magnetic resonance were both consistent with the diagnosis of mucinous cystadenoma. The patient was then
scheduled for a robot-assisted distal pancreatectomy with preservation of the spleen and the splenic vessels.
The procedure was completed safely in 255 minutes with minimal blood loss. The post-operative course was
uneventful and the patient was discharged on post-operative day 6. Final pathology confirmed the diagnosis
of mucinous cystadenoma. In the video presented herein we show the technique for robot-assisted distal
pancreatectomy with preservation of the spleen and the splenic vessels
Robot-assisted spleen preserving distal pancreatectomy (RA-SPDP): a single center experience
No full textAim: To define the outcome of robot-assisted spleen preserving distal pancreatectomy (RA-SPDP) in a highvolume
center.
Methods: A retrospective analysis of a prospectively maintained database was performed to identify RA-SPDP
performed at our Center between April 2008 to October 2017.
Results: During the study period, RA-SPDP was attempted in 54 patients. The spleen was preserved, always
along with the splenic vessels (Kimura procedure), in 52 patients (96.3%). There were no conversions to open
or laparoscopic surgery. Mean operative time was 260 min (231.3-360.0). Grade B post-operative pancreatic
fistula (POPF) occurred in 19 patients (35.2%). There were no grade C POPF. Two patients required repeat surgery
because of postoperative bleeding and splenic infarction, respectively. There were no post-operative deaths at
90 days. Excluding one patient with known diagnosis of metastasis from renal cell carcinoma, malignancy was
eventually identified in 7 of 53 patients (13.2%).
Conclusion: In the hands of dedicated pancreatic surgeons, robotic assistance results in a high rate of spleen
preservation with good clinical outcomes. Despite careful preoperative selection, several patients can be found to have a malignant tumor. Taken altogether these results suggest that patients requiring these procedures should be preferentially referred to specialized centers
L'ecografia nella diagnosi prenatale di displasie scheletriche
No full textLe displasie scheletriche sono un gruppo di oltre 400 patologie rare, a prognosi variabile e diverso rischio di ricorrenza. Scopo del presente lavoro è stato rivedere la casistica degli ultimi 30 anni in un singolo Centro di riferimento di ecografia ostetrica, per valutare le possibilità di diagnosi prenatale alle diverse età gestazionali.
Sono stati inclusi nello studio 29 feti riferiti per sospetto di malformazione e 11 feti di donne che avevano avuto un precedente feto con displasia scheletrica (2 casi di ricorrenza). Due neonati sono sopravvisuti, si sono avute 3 morti perinatali, in 18 casi la donna ha richiesto l’interruzione volontaria di gravidanza; gli ultimi 2 casi sono persi al follow-up. Le diagnosi erano: displasia tanatofora (n=8), osteogenesi imperfecta di tipo II (n=4), acondroplasia (n=3), sindrome di Shwachman-Diamond (n=2), disostosi spondilocostale (n=2) ed un caso ognuno di sindrome di Apert, ipocondrogenesi, ipofosfatasia ed ipostaturismo familiare. In 8 casi non è stato possibile effettuare una diagnosi esatta. La diagnosi è stata confermata con biologia molecolare in 13 casi, di cui 3 in epoca prenatale. Aspetti ecografici particolari erano riscontrabili nei casi di ipomineralizzazione, in 2/3 di acondroplasia (soltanto nel 3° trimestre), nei 2 di disostosi spondilocostale e nella sindrome di Apert
Duodenocefalopancreasectomia robotica: definizione di un modello predittivo preoperatorio di difficolta'
No full textAlcune evidenze mostrano che la duodenocefalopancreasectomia minimamente invasiva è associata a risultati migliori rispetto all'intervento chirurgico "open". Tuttavia, durante la fase di apprendimento, la sicurezza del paziente o l'efficacia oncologica potrebbero essere compromesse, sollevando così preoccupazioni sull'attuazione sicura dell'intervento. Il sistema chirurgico Da Vinci potrebbe abbreviare la curva di apprendimento e facilitare questo processo, anche se mancano prove chiare della superiorità della duodenocefalopancreasectomia robotica rispetto ad altri tipi di duodenocefalopancreasectomie mini-invasive (laparoscopica o ibrida) o open. Chiaramente ci sono diverse variabili correlate al paziente ed alla patologia di base che possono rendere un'operazione relativamente "semplice", con esito favorevole, o estremamente complessa, con un difficoltoso decorso postoperatorio. La capacità di prevedere la difficoltà della duodenocefalopancreasectomai robotica in ogni singolo paziente è estremamente importante sia per la selezione dei pazienti che per l'implementazione della learning curve
Comparison of drb1 and dqb1 allele frequencies and pre-transplant anti-hla antibodies in patients waiting for pancreas vs. kidney transplant. Abstracts of the 20th Biennial European Society for Organ Transplantation (ESOT) Congress
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