1,721,411 research outputs found
Long-Lasting Nanoscale Wireless Communications with Energy-Harvesting
Full text linkIl progresso tecnologico innescato dalle nanotecnologie ha recentemente promosso lo sviluppo di nanodispositivi che abilitano differenti nuove promettenti applicazioni in diversi campi. Data la dimensione limitata dei nano-dispositivi, la letteratura scientifica ha introdotto due nuovi paradigmi di comunicazione per la loro interazione: comunicazioni nella banda dei terahertz e comunicazioni molecolari. Tuttavia, la progettazione di schemi di trasmissione di lunga durata (cioè supportati da fonti energetiche rinnovabili) in questo contesto rappresenta ancora un argomento di ricerca inesplorato. Negli ultimi anni, i nanogeneratori piezoelettrici sono emersi come un punto di svolta nella progettazione di schemi di trasmissione basati sulla raccolta di energia su scala nanometrica. Di conseguenza, questa tesi considera la loro adozione nelle comunicazioni elettromagnetiche in banda terahertz e nelle comunicazioni molecolari basate sulla diffusione, proponendo strategie di controllo della potenza in trasmissione basate sulla teoria del controllo in retroazione. Nel dettaglio, la potenza di trasmissione viene impostata dinamicamente in modo proporzionale al budget energetico utilizzando uno schema di controllo ad anello chiuso. Inoltre, per quanto riguarda le comunicazioni molecolari basate sulla libera diffusione, questa tesi propone una nuova metodologia per calcolare il numero di molecole ottimale da rilasciare per ogni frame, garantendo sia la semplicità del processo di trasmissione che i vincoli energetici e i valori di Bit Error Rate predefiniti. A tal fine, la tesi formula anche un problema di ottimizzazione con lo scopo di minimizzare una funzione obiettivo dipendente dalla quantità di energia disponibile e dal numero di pacchetti in coda. Le simulazioni sono state utilizzate per convalidare i modelli analitici formulati, rappresentare il comportamento degli approcci proposti in scenari realistici e dimostrare la capacità unica degli approcci concepiti di garantire il livello di prestazioni previsto.The advance of nanotechnologies recently promoted the development of nanodevices enabling promising applications in different fields. Given the restricted size of nano-devices, the scientific literature introduced two novel communication paradigms for their interaction: terahertz band communications and molecular communications. However, the design of long-lasting transmission schemes (i.e., supported by renewable energy sources) in this context still represents an open research topic. In the last years, piezoelectric nanogenerators emerged as a turning point in the design of energy-aware and energy harvesting transmission schemes at the nanoscale. Accordingly, this thesis considers their adoption in electromagnetic communications in the terahertz band and in diffusion-based molecular communications, proposing power control strategies based on feedback control theory. Here, the transmission power is dynamically set proportionally to the available energy budget by using a closed-loop control scheme. Furthermore, concerning the diffusion-based molecular communications, this thesis proposes a novel methodology for optimally tuning the number of molecules to release on a per-frame basis, while guaranteeing the simplicity of the transmission process, energy constraints and target Bit Error Rate values. To this end, the thesis also formulates an optimization problem willing to minimize an objective function depending on the available energy budget and the number of enqueued packets. Computer simulations are used to validate the formulated analytical models, depict the behavior of the proposed approaches in conceivable scenarios, and demonstrate the unique ability of the conceived approaches to ensure the expected performance level
Design, Synthesis and Evaluation. Int J Mol Sci. 2025 Jun 25;26(13):6090
No full textAmong the fundamental pathological processes, tumorigenesis is arguably the most complex. It results from the accumulation of genetic alterations that typically unfold over many years, leading to the gradual breakdown of homeostatic barriers at the cellular, tissue, and ultimately organismal levels. Over the past few decades, discoveries on the molecular and cellular mechanisms of tumorigenesis have had, and continue to have, a profound impact on anticancer pharmacotherapy. It is noteworthy that since the early 2000s, the number of anticancer drugs approved for clinical use has increased from a few dozen [1] to several hundred distinct agents [2]. With the aim of targeting the hallmarks of tumorigenesis [3]—the functional traits that enable cancer cells to survive, proliferate, and disseminate—numerous classes of anticancer drugs are currently under active investigation and development. This Special Issue on “New Anticancer Agents: Design, Synthesis and Evaluation” brings together experimental studies and review articles that, at least in part, reflect the complexity of this disease and highlight several aspects of basic research aimed at therapeutic innovation
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
