1,720,963 research outputs found
“Follow-up dell’inquinamento da policlorobifenili (PCB) nel suolo e prodotti agricoli”
No full textJura Medic
Validation of an extraction and GC-MS quantification method of cocaine, methadone,and morphine in post-mortem adipose tissue
No full textAbstract
Adipose tissue is a complex biological matrix that necessitates several pre-analytical preparation steps to separate drugs and metabolites from the lipophilic matrix. A novel, sensitive, and specific gas chromatographic-mass spectrometric (GC-MS) method for the determination of cocaine (metabolites), methadone, and morphine in postmortem adipose tissue was developed, optimized, and validated. The method involves the aqueous acid extraction of analytes, alkalinization of the extract, solid-phase extraction with chloroform, and derivatization with BSTFA before GC-MS analysis. Deuterated compounds were used as internal standards for determination and quantification of analytes. Limits of detection were 0.005 μg/g for cocaine and cocaethylene, 0.02 μg/g for benzoylecgonine, 0.01 μg/g for ecgoninemethylester, 0.005 μg/g for methadone, and 0.01 μg/g for morphine. Linearity ranged from 0.1 to 1.000 μg/g for all analytes. Intra- and interday accuracy ranged from 70.6 to 105%, and intra- and interday precisions were less than 8.2% and 8.6%, respectively, for all analytes. The method showed a good recover
Validity of The Cozart Rapiscan Test for drug of abuse screening in hair by GC/MS Confirmation
No full textThis presentation will impact the forensic community and/or humanity by providing information on the testing of drugs of abuse in hair.
This project was carried out to evaluate the performance characteristic of the immunoassay Cozart Rapiscan oral fluid Test® for drugs of abuse screening in hair extracts.
The Cozart Rapiscan oral fluid Test® revealed good sensitivity and maximum specificity, proving to be a valid method of screening. To ensure the legal validity, confirmation analysis with chromatographic techniques (GC/MS or HPLC/MS) is required
Detection of cocaine and morphine in hair by Cozart Rapiscan oral fluid test
No full textnot availabl
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Post-mortem and adipose tissue: comparison of two biological alternative matrices to reveal illicit drugs abuse
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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