198,645 research outputs found
Voxel-based meta-analysis of regional white-matter volume differences in autism spectrum disorder versus healthy controls
No full textBackground We conducted a meta-analysis of voxel-based morphometry (VBM) studies in autism spectrum disorder (ASD) to clarify the changes in regional white-matter volume underpinning this condition, and generated an online database to facilitate replication and further analyses by other researchers.Method PubMed, ScienceDirect, Web of Knowledge and Scopus databases were searched between 2002 (the date of the first white-matter VBM study in ASD) and 2010. Manual searches were also conducted. Authors were contacted to obtain additional data. Coordinates were extracted from clusters of significant white-matter difference between patients and controls. A new template for white matter was created for the signed differential mapping (SDM) meta-analytic method. A diffusion tensor imaging (DTI)-derived atlas was used to optimally localize the changes in white-matter volume.Results Thirteen datasets comprising 246 patients with ASD and 237 healthy controls met inclusion criteria. No between-group differences were found in global white-matter volumes. ASD patients showed increases of white-matter volume in the right arcuate fasciculus and also in the left inferior fronto-occipital and uncinate fasciculi. These findings remained unchanged in quartile and jackknife sensitivity analyses and also in subgroup analyses (pediatric versus adult samples).Conclusions Patients with ASD display increases of white-matter volume in tracts known to be important for language and social cognition. Whether the results apply to individuals with lower IQ or younger age and whether there are meaningful neurobiological differences between the subtypes of ASD remain to be investigated. © 2011 Cambridge University Press
A general approach for combining voxel-based meta-analyses conducted in different neuroimaging modalities
No full textMeta-analyses are useful to summarize the exponential amount of inconsistent and conflicting neuroimaging data. However, they are usually separately conducted for each different neuroimaging modality, preventing the multimodal integration of different imaging findings in a given neuropsychiatric disorder. Here, we describe an innovative method to meta-analytically combine the results of different imaging modalities, such as structural and functional paradigms. The method accounts for the presence of noise in the estimation of the p-values, and can be easily applied to any meta-analytical software. We hope that with this advanced imaging tool, researchers will be able to provide more complete multimodal pictures of the brain regions affected in different neuropsychiatric disorders
Joannes Maior in primu[m][-secundum] sententiarum
No full textSign.: [ ]2, b-p8, q10, r8Tipus gòtics i 2 cols. - Capll. orn
Joannes Maior in primu[m][-secundum] sententiarum.
No full textSign.: [ ]2, b-p8, q10, r8Tipus gòtics i 2 cols. - Capll. or
Analysis of the precipitation and cloudiness associated with COLs occurrence in the Iberian Peninsula
No full text© Springer-Verlag 2006. This work was supported by the Spanish Ministry of Science and Technology (MCYT) under Grant REN2002-04558-C04- 01=02=03=04 and by the Galician Programme of Research and Development under Grant GIDIT03PXIC38301PN. This work was supported also by a postdoctoral fee (SFRH= BPD=22178=2005) to the principal author from the FCT of Portuguese Ministry of Science, Technology and Education. The authors wish to thank the Spanish National Meteorology Institute (INM) for providing the data analysed in this study.The Iberian Peninsula is one of the regions in the world with higher occurrence of cut-off low systems (COL). The aim of this paper is to analyse the weather events (rainfall and cloudiness layer) associated to COLs in the Iberian Peninsula with tools not previously used: (a) the use of the new multidecadal COLs database developed by Nieto et al (2005) that permit us to study a 41 years period (1958-1998), (b) the checking of the expected weather events (rainfall and cloudiness layer) associated with COLs in a conceptual model (Winkler et al, 2005) and (c) the extensive use of radiosoundings to analyse convective instability in areas inside and close to the COL. Two points of view are used to make the analysis: (1) a source oriented method, when a particular COL is followed and its associated precipitation and cloudiness is analysed over four quadrants in which Iberia was divided and (2) a receptor oriented method, when the precipitation associated to COLs is analysed in given areas, defined by patterns of precipitation. Results reveal that the precipitation and cloudiness patterns associated to COLs in the conceptual model reproduce quite well the main characteristics found over the Iberian Peninsula. The generalized idea that most of the COLs produce intense convective rainfall is show to be misleading. Convective phenomena are important usually when the centre of the COL is located on the Mediterranean region. Most of the rainfall associated with COLs comes from the baroclinic shield; specially in cases located over the west half of the Iberian Peninsula. It is shown that nearly 30% of COLs do not induce any rainfall; most of them located in the southern half of the Peninsula, and mainly during autumn. Only 30% of COLs produce generalized rainfall over the whole analysed territory, being most of them (about 90%) located over the western half of the Iberian Peninsula.Ministerio de Ciencia y Tecnología (España)Xunta de GaliciaFundação para a Ciência e a Tecnologia (Portugal)Depto. de Física de la Tierra y AstrofísicaFac. de Ciencias FísicasTRUEpu
Philibert Russo, Témoins de la surface pliocène de 200 m. de la Loire moyenne, dans les cols du Haut Charollais
No full textA. A. Philibert Russo, Témoins de la surface pliocène de 200 m. de la Loire moyenne, dans les cols du Haut Charollais. In: Revue de géographie jointe au Bulletin de la Société de géographie de Lyon et de la région lyonnaise, vol. 24, n°1, 1949. p. 86
The use of a nonimmersive virtual reality programme in Anorexia nervosa: A single case-report
No full textObjective: People with anorexia nervosa (AN) experience high levels of fear and anxiety related to eating. The aim of this case report was to describe the use of a virtual reality (VR) programme developed to facilitate exposure to food as a supplement to treatment for a person with AN. Method: A 21-year-old patient with AN was given the VR module in addition to the Maudsley Model of Treatment for Adults with Anorexia Nervosa. Weight, eating disorder symptomatology (EDE-Q) and general psychopathology (DASS) were assessed before and after the module was delivered. Results: At the end of the module, the patient reported lower levels of anxiety, safety behaviours and fears related to food. Both eating disorder symptoms and distress were reduced. Body mass index increased from 15 to 16.8kg/m 2 during the module. Conclusion: The VR exposure module was associated with a beneficial change in the relationship to food and was perceived to be helpful by the individual. Copyright © 2011 John Wiley & Sons, Ltd and Eating Disorders Association
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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