1,720,988 research outputs found
Use of long-acting antipsychotic medications: Practical issues
No full textIntroduction Non-adherence to therapy is a significant problem in treatment of patients with a diagnosis of schizophrenia; the rate of non-adherence in psychiatric patients varies from 24% to 90%, with average of about 60%. This may be due to the lack of awareness of the disorder, weak conviction of the utility of therapy by the patient or family, complexity of treatment, or severity of side effects. To increase adherence to treatment formulations of extended- release injectable antipsychotics (long-acting injectable, LAI) have been developed that ensure a continuous supply of the drug with stable blood concentrations. Objective The objective of this review is to evaluate the advantages and disadvantages of LAI antipsychotics, the main guidelines, and attitudes of the physician and patient to their prescription and administration. Methods Review of the literature using PubMed. The keywords "antipsychotic long-acting", "LAI", "schizophrenia", "poor compliance" and "antipsychotic depot" were used. Conclusions Many authors agree on the poor use of LAI in clinical practice due to the lack of knowledge of the type of drug by both physicians and patients. A careful examination of guidelines may help to identify the ideal profile of patients who can benefit from LAI
Construct and concurrent validity of the Italian version of the Brief Multidimensional Measure of Religiousness/Spirituality.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Which metacognitive components of insight in schizophrenia? The relationship between subjective and objective measures of metacognition and insight
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Validation of a brief version of the resilience scale for adults on an Italian non-clinical sample
No full textAim. The Resilience Scale for Adults (RSA) is a self-administered 7-point Likert scale of 33 items, structured in 6 factors measuring personal and interpersonal resources. We aimed to develop and validate a brief form of the RSA, in order to produce a short, fast and handy tool for assessing resilience. Materials and methods. A non-clinical sample of 500 university students was recruited using a research website. Reduction of the RSA-33 was performed using an item response theory (IRT) analysis by means of a Graded Response Model (GRM) protocol on the 6 RSA factors separately. After the IRT reduction process, a Pearson's correlation matrix of the original RSA-33 and the reduced version was estimated. Finally, a CFA was estimated to assess factorial validity. The estimation of item discrimination from the GRM ranged from 0.69 and 5.94 and allowed to retain 11 items. Results. For both the original RSA-33 and the brief RSA-11, the strongest correlations were between Family Cohesion and Social Resources factors. CFA was estimated to assess factorial validity in a simplified model with two latent first-order factors, i.e., Personal and Contextual resources. Conclusions. The availability of short and psychometrically robust measures is needed to improve evaluation and monitoring in mental health programs. For this reason, we provided a brief and effective tool to assess resilience resources in both research and clinical settings
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