1,721,115 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Les récepteurs Tyrosine kinases de Schistosoma mansoni : à la recherche de nouvelles cibles thérapeutiques
No full textMalgré les efforts entrepris pour contrôler sa transmission, la schistosomose reste la seconde endémie parasitaire mondiale et représente toujours un véritable problème de santé publique ainsi qu’un handicap pour la croissance économique de bon nombre de pays en voie de développement. Dans le cas de l’infection à Schistosoma mansoni, l’apparition de cas de résistance au praziquantel, drogue de choix actuelle pour le traitement de la maladie, représente une menace importante pour la santé des populations et motive la poursuite de recherches visant à la découverte de nouvelles molécules. Les récents succès obtenus en chimiothérapie anticancéreuse avec l’utilisation d’inhibiteurs spécifiques de récepteurs tyrosine kinases (RTK), tel que le récepteur EGF, nous ont conduits à considérer que, d’une manière analogue, les récepteurs aux facteurs de croissance du parasite pourraient être des cibles thérapeutiques potentielles. Trois RTK ont été identifiés chez S. mansoni : un récepteur de l’EGF, un récepteur de l’insuline et un récepteur complètement original appartenant probablement à une classe de RTK qui n’avait pas été encore identifiée. Les études structurales et fonctionnelles ont démontré la conservation et les divergences de ces RTK parasitaires et en font des candidats privilégiés en tant que nouvelles cibles chimiothérapeutiques
Venus Kinase Receptors at the crossroads of insulin signaling: their role in reproduction for helminths and insects
No full textVenus kinase receptors (VKRs) are invertebrate receptor tyrosine kinases (RTKs) first discovered in the human parasite Schistosoma. They contain an extracellular Venus FlyTrap (VFT) module similar to the ligand-binding domain of G protein-coupled receptors of class C and an intracellular tyrosine kinase domain similar to that of insulin receptors. VKRs are present from cnidarians to echinoderms. They were shown to be activated by amino-acids, to induce insulin-like intracellular pathways and to be highly expressed in larvae and in gonads of helminths and insects. The function of VKR in gametogenesis was demonstrated in schistosomes by VKR silencing and recent studies in Aedes aegypti have confirmed the importance of VKR in mosquito egg formation. AaeVKR was shown to bind to ovary ecdysteroidogenic hormone (OEH) and to activate the production of ecdysteroids by the ovary, independently of signaling mediated by insulin-like peptides. These new data confirm and specify the function of VKRs in the reproduction of helminths and insects and they open interesting perspectives for elucidating the role of VKRs in other models. VKR targeting would also provide opportunities for the control of parasites and various vector-borne diseases
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Les récepteurs Tyrosine kinases de Schistosoma mansoni : à la recherche de nouvelles cibles thérapeutiques
No full textkoamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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