201 research outputs found
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Literature Search and Application: Interventions for Children with Insulin-dependent Diabetes Mellitus
No full textThis article presents the results of a literature search designed to demonstrate the guidelines for conducting an evidence-based investigation as outlined by Leonard Gibbs (2003) and to identify interventions used in the psychosocial treatment of children with insulin-dependent diabetes mellitus (IDDM). The article will also propose strategies to apply and implement those interventions in a treatment plan for patients and families at Children’s Memorial Hospital in Chicago. Application and implementation strategies focus on a community-based, family support intervention adapted to fit the needs of the hospital’s patient and family population, as well as the parameters of the hospital setting
Managing food safety and hygiene: governance and regulation as risk management
No full textFood safety and hygiene is of critical importance to us all. In this wide ranging book, Bridget Hutter explores how we are all dependent on others to ensure that the food we consume from food in the retailing and hospitality sectors is safe. This has prompted a governance system embracing state regulation and groups beyond the state such as consumers, insurance, media and businesses themselves. The book argues that state regulation is ‘necessary but not sufficient’ as an influence on business risk management practices. Using research data from the UK, the author examines the relative importance of these other groups, in relation to each other and in relation to state regulation
The effect of reinforcement on loadbearing capacity of structural glass
No full textThesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 49-50).The transparent property of glass makes it a favored choice of material in the design of structures because it maximizes light and creates an illusion of larger spaces. However, it is a very brittle, making it difficult to use as a common building material. Laminated glass significantly improves the strength through a layer of resin called polyvinyl butyral (PVB). Laminated glass is typically used for buildings in which human impact is vulnerable, such as hurricane prone areas or important government buildings. However, laminated glass still lacks the residual loadbearing capacity that one would find in reinforced steel, for instance. Residual loadbearing capacity is important to ensure the safety and reliability of glass as a structural material. This thesis will provide an overview of the common glass treatments, fixings, structural systems, and design methods used today. Additionally, two research studies investigating the effects of reinforced glass will be examined. Finally, the author will provide a simulation of a three-layer laminated glass stair tread with an applied design load. The simulation compares the stresses and displacements of the unreinforced glass tread with a glass tread reinforced with a 4 mm thick steel plate. The results from the simulation are inconclusive. However, experimental results from the two research studies show promise for the use of reinforcement in glass to improve load bearing capacity.by Bridget I. Navarro.M.Eng
Independent and interacting effects of diet and genetic risk on obesity-related comorbidities
No full textIntroduction: Dyslipidemia results from behavioral and biological factors. Elevated triglyceride (TG) and decreased high-density lipoprotein cholesterol (HDL-C) concentrations are common in obesity. Dietary guidelines for dyslipidemia management encourage replacing saturated (SFA) with unsaturated fat (UFA) and increasing fiber intake. Diet alone does not produce metabolic disease, and genetic variation can increase dyslipidemia risk. Nutrigenetics is a body of research investigating dietary and genetic interactions, but less research exists in non-European populations and individuals with obesity. Our objective was to explore dietary and genetic factors associated with dyslipidemia in populations at risk for metabolic disease.
Methods: Meta-analysis of randomized controlled trials (RCT) was conducted investigating SFA-UFA replacement on total cholesterol (TC), HDL-C, and TG concentrations. Genetic contributions to dyslipidemia in Mexicans were explored through creation of a genetic risk score (GRS) from SNPs associated with dyslipidemia. Nutrigenetic interactions were explored in adults with obesity enrolled in a clinical trial, who were randomized to receive a meal with or without an avocado for 12 weeks. Interactions among dietary fat intake, genotype, and blood lipid concentrations were determined pre- and post-intervention.
Results: In a meta-analysis of 8 RCT, SFA-UFA replacement on TC concentrations approached significance (P=0.06) in favor of UFA intake. GRS was significantly associated with TG and HDL-C. Among adults enrolled in the clinical trial, dietary fat intake and genotype interactively impacted TC and HDL-C concentrations at baseline. Following dietary intervention, several gene-diet interactions were associated with changes in TC and HDL-C. The glucokinase regulator rs1260326 SNP was associated with TC changes, by which individuals in the avocado group experienced differential changes by presence or absence of the risk allele.
Conclusions: SFA-UFA replacement may not be effective in adults with obesity, yet remains a key recommendation in dietary guidelines. Cumulative genetic risk affects HDL-C and TG in the Mexican population, who experience increased dyslipidemia prevalence but remain underrepresented in genetic research. Nutrigenetic interactions between lipid-metabolism related SNPs and dietary fat intake were associated with blood lipid concentrations at baseline and following dietary fat modification. Exploring gene-diet interactions may provide insight into treatment response variability and the development of dyslipidemia despite behavioral risk.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2022-05-01The student, Bridget Hannon, accepted the attached license on 2020-04-19 at 13:09.The student, Bridget Hannon, submitted this Dissertation for approval on 2020-04-19 at 13:14.This Dissertation was approved for publication on 2020-04-22 at 16:07.DSpace SAF Submission Ingestion Package generated from Vireo submission #15003 on 2020-08-25 at 17:27:40Made available in DSpace on 2020-08-26T23:54:33Z (GMT). No. of bitstreams: 2
HANNON-DISSERTATION-2020.pdf: 4451134 bytes, checksum: 10648bfb38d1a19e3f08dc776af69cc6 (MD5)
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Previous issue date: 2020-04-22Embargo set by: Seth Robbins for item 115723
Lift date: 2022-08-26T23:54:40Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 115723
Lift date: 2022-08-26T23:55:59Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 115723
Lift date: 2022-08-26T23:57:28Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 115723
Lift date: 2022-08-26T23:58:55Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Onl
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The electric shepherd and the marvellous boy: literary evocations of Thomas Chatterton's 'suicide' in Philip K. Dick's 'A scanner darkly' and elsewhere
No full textSarah Fielding: Satire and Subversion in the Eighteenth-Century Novel
No full textThis study of Sarah Fielding (1710―68) is an original contribution to Fielding scholarship that has a dual purpose: to support those who are striving to re-introduce her to the modern literary landscape in an effort to restore her eighteenth-century literary standing, and to firmly establish Fielding as an early feminist writer. It is argued here that throughout her oeuvre Fielding challenged prevailing traditions that denied women a choice, particularly in education, employment and marriage. These themes are also considered in the political treatises of Mary Astell (1666―1731) and Mary Wollstonecraft (1759―97), who are now widely recognised as feminist writers.
It is further argued that Fielding’s subversion in fiction of the English patriarchal system is underscored by her unorthodox performance in the literary arena. This is fully explored alongside her use of sentimentalism as a literary tool with which she challenges her seemingly inhumane society. Fielding’s interest in ‘the Labyrinths of the Mind’ (in modern terms, human psychology) will also be addressed as will her placement in the history of feminism and her placement in the sentimental novel tradition. Fielding’s performance as a literary critic will be compared with the few female authors who, like her, dared to publish literary criticism during her writing career. Accordingly, extracts from Fielding’s novels and her two critical pamphlets will be thoroughly examined.
An updated biography of Fielding that is also included here will provide evidence for a further claim, that her fiction is autobiographical in part. A comprehensive account of Fielding’s performance as a literary critic forms the final chapter of this work. It is the first full-length examination of her contribution to the genre and includes an appraisal of her recently unearthed critical pamphlet entitled A Comparison Between the Horace of Corneille and The Roman Father of Mr. Whitehead (1750) that is yet to be formerly attributed to her. Ultimately this study of Fielding will go far beyond what has previously been written about this remarkable eighteenth-century author, particularly regarding her feminist activity
Time and the Human/Nature Relationship: An Examination of Alternative Temporalities in Contemporary Climate Fiction
No full textIn this three-part thesis, I examine three contemporary authors of climate fiction and how their works illustrate alternate views of time in their aims of creating more sustainable worlds. The first chapter focuses on Ursula Le Guin’s Always Coming Home (1985), in the second I examine Rebecca Roanhorse’s The Sixth World duology (2018-2019), and the final chapter explores N.K. Jemisin’s The Broken Earth series (2015-2017). Each work/series offers sustainable worldviews and ways of living that challenge dominant, global systems of imperialism/colonialism and capitalism. Through the lens of alternative temporalities, most often cyclical and ecologically regenerative, each author critiques the artificiality of linear, atomic time that has evolved to reflect the interests of western capitalism and global dominations at the cost of human and nonhuman life. As the global climate crisis worsens, it has become critical to not only examine the unsustainable components of contemporary worldviews, like that of the dominating West, but also portray solutions and imagine better worlds beyond today’s. In examining various temporalities and their resulting ecological sensibilities, I show how Le Guin, Roanhorse, and Jemisin each critique the societal structures that are clearly unsustainable in their dependence on human and natural exploitation, while illustrating worldviews that connect rather than separate the human and nonhuman. In doing so, I aim to illustrate the connection between cultural temporalities and their resulting ecological sensibilities, and point towards the sustainable, expanded, and complex worldviews Always Coming Home, The Sixth World, and The Broken Earth portray as we all seek to find sustainable ways of moving forward in the age of the Anthropocene.ProQuest Traditional Publishing Optio
A Refuge Remembered
No full textThe history of the author\u27s Kennebunkport home, a barn refurbished as living quarters. Details the progress of the barn, on land once known as Freedom Farm, from the property of an invalided dairy farmer to the refuge of twenty-eight Eastern European displaced persons after World War II, including Zbig Kurlanski, a refugee from Russia who came to the farm at the age of 4 with his mother and brothers, and is now the author\u27s neighbor
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