1,762 research outputs found

    Science Fiction Collections in ARL Academic Libraries

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    This study assesses the extent to which ARL academic libraries collect science fiction novels. A core list of 200 novels, published between 1950 and 2000, that have either won science fiction awards or been cited on “best” lists were checked against the holdings of 112 ARL libraries. Findings suggest that science fiction is not extensively collected at most libraries studied. The study also assesses differences in how novels are collected by date and by nationality and gender of author. To support in-depth and serious research in a field of increasing scholarly interest, libraries may need to reconsider their collecting practices.The published version of this article appears in College & Research Libraries, and is available at this location: crl.acrl.org/content/67/1/15.full.pdf‎Peer reviewe

    Mapping the global geographic potential of Zika virus spread

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    This paper was submitted to the Memórias do Instituto Oswaldo Cruz on 14 April 2016 and was posted to the Zika Fast Track site on 15 April 2016, according to the protocol for public health emergencies for international concern as described in Dye et al. (2016) (http://dx.doi.org/10.2471/BLT.16.170860).Per the policy of Memórias do Instituto Oswaldo Cruz, the DOI listed in this record will not be active until the article is published in the journal.The Americas are presently experiencing the most serious outbreak of Zika virus (ZIKV) known. Here, we present a novel set of analyses using environmental characteristics, vector distributions, and socioeconomic risk factors to develop the first map to detail global ZIKV transmission risk in multiple dimensions based on ecological niche models. Our model predictions were tested against independent evaluation data sets, and all models had predictive ability significantly better than random expectations. The study addresses urgent knowledge gaps regarding the potential geographic scope of the current ZIKV epidemic, as well as the global potential for spread. It also provides a highly informative view of potential drivers of ZIKV distributions globally, pointing out areas vulnerable in terms of some drivers, but not in others. The results of these analyses can guide regional education and preparedness efforts, such that medical personnel will be prepared for diagnosis of potential ZIKV cases as they appear

    Polymer based immune modulation for the generation of an anti-tumor immune response

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    Increasing emphasis is being placed on overcoming tumor-associate immune escape mechanisms that facilitate disease progression. Understanding this immune tolerance and developing methods to overcome it provide advanced understanding to further develop vaccine strategies. In the current work we have engineered a polymer based therapy that enhances cellular immunity capable of generating anti-tumor activity. We have determined that a poly(lactic-co-glycolic acid) (PLGA) based delivery system encapsulating tumor associated antigen (ovalbumin, OVA) and the TLR9 agonist CpG motif DNA can initiate an effective type 1 mediated response. Local administration of the polymer therapy on E.G7-OVA lymphoma bearing mice significantly delayed tumor progression by eliciting a strong local and systemic IFN-γ mediated anti-tumor response. It was found that this response worked independently of antigen specific CTLs, which were active in the tumor draining lymph nodes yet incapable of retarding tumor formation. In analyzing the dendritic cell response to this polymer system, it was demonstrated that this delivery system indeed increased the Th1 phenotype of dendritic cells as measured by an increase in cell surface expression of CD80, CD86 and MHCII and secretion of the cytokines IL-12 and IFN-γ. In addition, introducing the immune modulator 1-Methyl Tryptophan (1-MT) in concert with the antigen and adjuvant enhanced the dendritic cell Th1 profile when delivered via the PLGA vesicle. Taken together, these studies demonstrate the immunological mechanisms and benefits of a PLGA based delivery system.Ph. D.Includes bibliographical referencesby Kevin P. Nikitczu

    Productivity in Higher Education/ Kevin Stange, Kevin Strange, Caroline M. Hoxby.

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    In English.How do the benefits of higher education compare with its costs, and how does this comparison vary across individuals and institutions? These questions are fundamental to quantifying the productivity of the education sector. The studies in Productivity in Higher Education use rich and novel administrative data, modern econometric methods, and careful institutional analysis to explore productivity issues. The authors examine the returns to undergraduate education, differences in costs by major, the productivity of for-profit schools, the productivity of various types of faculty and of outcomes, the effects of online education on the higher education market, and the ways in which the productivity of different institutions responds to market forces. The analyses recognize five key challenges to assessing productivity in higher education: the potential for multiple student outcomes in terms of skills, earnings, invention, and employment; the fact that colleges and universities are "multiproduct" firms that conduct varied activities across many domains; the fact that students select which school to attend based in part on their aptitude; the difficulty of attributing outcomes to individual institutions when students attend more than one; and the possibility that some of the benefits of higher education may arise from the system as a whole rather than from a single institution. The findings and the approaches illustrated can facilitate decision-making processes in higher education.Hoxby, Caroline M. / Stange, Kevin -- Staiger, Douglas -- Hoxby, Caroline M. -- Minaya, Veronica / Scott-Clayton, Judith -- Riehl, Evan / Saavedra, Juan E. / Urquiola, Miguel -- Altonji, Joseph G. / Zimmerman, Seth D. -- Courant, Paul N. / Turner, Sarah -- Vlieger, Pieter De / Jacob, Brian / Stange, Kevin -- Deming, David J. / Lovenheim, Michael / Patterson, Richard -- Carrell, Scott E. / Kurlaender, Michal -- Frontmatter -- Contents -- Acknowledgments -- Introduction / 1. What Health Care Teaches Us about Measuring Productivity in Higher Education / 2. The Productivity of US Postsecondary Institutions / 3. Labor Market Outcomes and Postsecondary Accountability: Are Imperfect Metrics Better Than None? / 4. Learning and Earning: An Approximation to College Value Added in Two Dimensions / 5. The Costs of and Net Returns to College Major / 6. Faculty Deployment in Research Universities / 7. Measuring Instructor Effectiveness in Higher Education / 8. The Competitive Effects of Online Education / 9. Estimating the Productivity of Community Colleges in Paving the Road to Four- Year College Success / Contributors -- Author Index -- Subject Index1 online resource (392 p.)

    Music for classical guitar by South African composers : a historical survey, notes on selected works and a general catalogue

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    Includes abstract.Includes bibliographical references (leaves 296-309).This is the first comprehensive investigation of music for, or including, the classical guitar by South African composers. The focus of this research has been, firstly, to uncover as much of the repertoire as possible, and, secondly, to collate, study, catalogue and report on the information. A brief historical survey of the guitar in South Africa provides the context within which this study was conducted. The primary sources of quantitative data collection were through the archival catalogues of the South African Music Rights Organisation and through personal contact with guitarists, composers and guitar teachers. Other sources consulted were publishers, broadcasting corporations, recording companies, libraries and the internet. The body of the dissertation comprises biographical sketches, background notes, analyses and technical notes on 17 selected solo and chamber works dating from 1947 to 2007 by some of South Africa's most prominent composers and guitaristcomposers. The repertoire ranges in style from the traditional and ethnically inspired to the experimental and abstract. As this is an empirical survey, each selected entry includes details on instrumentation, duration, level of difficulty, number of pages, scordatura, commissions or requests, sources or publishers, premières and recordings. A biography of each composer is provided as well as background notes which offer an overview of the selected work. The notes discuss historical, cultural, musical and extra-musical influences, and frequently include references to interview material. The commentaries on the selected works, with musical examples, include an analytical component describing structure, form, stylistic and compositional elements, while the technical observations include performance suggestions and a grading for each work

    Fixing Australia’s incredible defence policy

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    Australia’s new government must make tough decisions in defence policy. Australia’s broad national interests and the challenging strategic environment in Indo-Pacific Asia make it essential to modernise the Australian Defence Force. The nation’s defence capabilities remain underfunded and its strategic edge in the region is eroding. The gap between the nation’s interests and capabilities is widening, and it is getting harder to meet the demands of the US alliance. Australia’s new government needs to restore focus and funding to defence.Key findings: The Australian government will need a first-principles review to identify the military strategy and force structure required to protect and advance the nation’s interests. The Australian government must increase defence funding in order to modernise the Australian Defence Force\u27s capabilities. Otherwise it will need to make drastic cuts to planned defence capability. The government must also think deeply about the role of the US alliance in Australia\u27s security, and take the initiative in shaping that alliance in Australia’s interests

    Wealth reallocation and sustainability under climate change

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    Climate change is often described as the greatest environmental challenge of our time. In addition, a changing climate can reallocate natural capital, change the value of all forms of capital and lead to mass redistribution of wealth. Here we explain how the inclusive wealth framework provides a means to measure shifts in the amounts and distribution of wealth induced by climate change. Biophysical effects on prices, pre-existing institutions and socio-ecological changes related to shifts in climate cause wealth to change in ways not correlated with biophysical changes. This implies that sustainable development in the face of climate change requires a coherent approach that integrates biophysical and social measurement. Inclusive wealth provides a measure that indicates sustainability and has the added benefit of providing an organizational framework for integrating the multiple disciplines studying global change.Peer reviewe

    PEMBUATAN TOKO ONLINE PENJUALAN BATIK MENGUNAKAN TEMPLATE TOKOTALK

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    n this thesis the author focuses on the preparation of Digital Marketing in the store Batik Zalina Surabaya in the millennial period which aims to facilitate for saller and buyers . The author conducted field worlk practices for 4 month at Batik Zalina Surabaya Store in the digital marketing section . The result of the task end done by author is able to know what should be in do it in preparing for digital marketing in the milenial era

    Bipolar thermoelectric devices

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.Includes bibliographical references (p. 124-133).This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.The work presented here is a theoretical and experimental study of heat production and transport in bipolar electrical devices, with detailed treatment of thermoelectric effects. Both homojunction and heterojunction devices are considered, and particular attention is given to semiconductor laser diodes. The mechanisms that govern both internal heat exchange and heat transfer between a device and its environment are examined, leading to structures which are optimized for thermal management.by Kevin Patrick Pipe.Ph.D

    Vascular Disorders in the Athlete

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