48,828 research outputs found
Prenatal Stress Diminishes the Cytokine Response of Leukocytes to Endotoxin Stimulation in Juvenile Rhesus Monkeys
No full textSeawater redox variations during the deposition of the Kimmeridge Clay Formation, United Kingdom (Upper Jurassic): evidence from molybdenum isotopes and trace metal ratios
No full textThe Kimmeridge Clay Formation (KCF) and its equivalents worldwide represent one of the most prolonged periods of organic carbon accumulation of the Mesozoic. In this study, we use the molybdenum (Mo) stable isotope system in conjunction with a range of trace metal paleoredox proxies to assess how seawater redox varied both locally and globally during the deposition of the KCF. Facies with lower organic carbon contents (TOC 1–7 wt %) were deposited under mildly reducing (suboxic) conditions, while organic-rich facies (TOC >7 wt %) accumulated under more strongly reducing (anoxic or euxinic) local conditions. Trace metal abundances are closely linked to TOC content, suggesting that the intensity of reducing conditions varied repeatedly during the deposition of the KCF and may have been related to orbitally controlled climate changes. Long-term variations in ?98/95Mo are associated with the formation of organic-rich intervals and are related to third-order fluctuations in relative sea level. Differences in the mean ?98/95Mo composition of the organic-rich intervals suggest that the global distribution of reducing conditions was more extensive during the deposition of the Pectinatites wheatleyensis and lower Pectinatites hudlestoni zones than during the deposition of the upper Pectinatites hudlestoni and Pectinatites pectinatus zones. The global extent of reducing conditions during the Kimmerigidan was greater than today but was less widespread than during the Toarcian (Early Jurassic) oceanic anoxic event. This study also demonstrates that the Mo isotope system in Jurassic seawater responded to changes in redox conditions in a manner consistent with its behavior in present-day sedimentary environment
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Sequence stratigraphy: using changes in relative sea-level and sediment supply to divide, correlate and understand the stratigraphical record
No full textChapter 8 of Deciphering Earth’s History: the Practice of Stratigraphy takes a pragmatic step-by step approach to show how the sequence stratigraphy model can be applied to the full range of sedimentary strata. The chapter demonstrates how this holistic technique can be used to gain valuable insights for stratigraphical correlation, predict facies distributions, establish changes in relative sea-level and help detect hiatuses and changes in sedimentation rate and hence assist in deciphering the chronostratigraphy of successions. There is emphasis on real-world challenges and how the sequence stratigraphy framework complements and provides possible frameworks for other stratigraphical techniques
Hybrid bounds for twisted L-functions
No full textThe aim of this paper is to derive bounds on the critical line Rs 1/2 for L- functions attached to twists f circle times chi of a primitive cusp form f of level N and a primitive character modulo q that break convexity simultaneously in the s and q aspects. If f has trivial nebentypus, it is shown that
L(f circle times chi, s) << (N vertical bar s vertical bar q)(epsilon) N-4/5(vertical bar s vertical bar q)(1/2-1/40),
where the implied constant depends only on epsilon > 0 and the archimedean parameter of f. To this end, two independent methods are employed to show
L(f circle times chi, s) << (N vertical bar s vertical bar q)(epsilon) N-1/2 vertical bar S vertical bar(1/2)q(3/8) and
L(g,s) << D-2/3 vertical bar S vertical bar(5/12)
for any primitive cusp form g of level D and arbitrary nebentypus (not necessarily a twist f circle times chi of level D vertical bar Nq(2))
Carinomella lactea Coe 1905
No full textCarinomella cf. lactea Coe, 1905 (Figure 2 [2 a– 2 b]) Carinomella lactea: Coe, 1905: 127, Pl. 5, figs. 45–49, Pl. 6, figs. 50–54, Pl. 7, figs. 55, 56, Pl. 8, figs. 57, 58, Pl. 9, figs. 59–61, Pl. 10, figs. 63–65, Pl. 11, figs. 66 – 62; Boesch, 1973: 230; Turbeville & Ruppert, 1983: 103; Fox & Ruppert, 1985: 37; Norenburg, 1993: 212; Hochberg & Lunianski, 1998: 295; Ritger & Norenburg, 2006: 941; Turbeville, 2006: 968, figs. 4, 5, 6 c; Chernyshev, 2010: 2288. Material examined. One specimen (26 mm), MZUSP 0 0 0 12, Brazil, Ceará, Paracuru, Praia da Pedra Rachada, 3 ° 23.95 ' S 39 ° 0.85 ' W, on mud sand, coll. Cecili Mendes, 16. VI. 2014. Field diagnosis. Body small, rounded anteriorly, flattened intestinal region; translucent, whitish anteriorly and yellowish-orange posteriorly. No eye spots, white dorsomedian line on head. Large mouth, immediately posterior to cerebral ganglia. Alimentary canal divided into two portions, anterior clear and less opaque than yellowish intestinal region, as seen by Coe (1905). Lateral organs present posterior to start of intestine; circular orange band formed in this region after preservation. Distribution. Western Atlantic: USA (Florida [Corrêa 1961], South Carolina [Fox & Ruppert 1985] and Virginia [Boesch 1973]) and Brazil (Ceará [present study]) Eastern Pacific: USA (California [Coe, 1905]) Ecology. The present specimen was found in muddy sand, under rocks in the lower intertidal zone, which agrees with Coe (1905). However, Corrêa (1961) reports a specimen dredged from about 4 m in Biscayne Bay. Remarks. This species can be confused with Carinoma mutabilis because of the ground color, but C. mutabilis lacks lateral sense organs. Identification of the present specimens remains uncertain because there are few internal and external characters that can be compared with other species. A firmer identification awaits genetic study. A factor favouring the probability that this is conspecific with worms reported as C. lactea from Florida is the significant taxonomic overlap among nemerteans from Florida and Brazil. However, given the lack of morphological diagnostics, the identity for all Atlantic reports of this species must be held in doubt until compared with northeastern Pacific Ocean specimens from the vicinity of the type locale.Published as part of Mendes, Cecili B., Matthews-Cascon, Helena & Norenburg, Jon L., 2016, New records of ribbon worms (Nemertea) from Ceará, Northeast Brazil, pp. 146-156 in Zootaxa 4061 (2) on page 149, DOI: 10.11646/zootaxa.4061.2.4, http://zenodo.org/record/26358
Letter - House of Representatives
No full textLetter: From Mrs. Jo-Anne L. Coe, to Stewart Udall, September 11, 1961HAROLD D. COOLEY
NORTH CAROLINA
CHAIRMAN:
COMMITTEE ON AGRICULTURE
HOME ADDRESS:
NASHVILLE, NORTH CAROLINA
Congress of the United States
HOUSE OF REPRESENTATIVES
WASHINGTON, D. C.
September 11, 1961
Honorable Stewart L. Udall
Secretary
Department of the Interior
Washington 25, D. C.
Dear Mr. Secretary:
Mr. Cooley received and read with great interest your letter dated September first, urging his support of the Public Works Appropriations Bill. He has had an extremely busy schedule and left Saturday afternoon to attend the Fiftieth Annual Meeting of the Interparliamentary Union in Brussels. As you know, he is a Member of the Executive Committee of this great and ancient "peace organization", with which fifty nations of the world are now affiliated. Prior to his departure, however, he did ask me to write to you and acknowledge receipt of and thank you for your letter.
I do know that the Congressman appreciated very much your thoughtfulness in writing to him about this bill, and I am certain he regrets his inability to be present tomorrow when the vote is taken on this measure.
With cordial good wishes, I am
Sincerely yours,
Mrs. Jo-Anne L. Coe
SecretaryEpson Perfection 4870 Photo, 400 dpi, 24 bit, 2,155,394 byte
XMM-Newton observation of the highly magnetised accreting pulsar Swift J045106.8-694803: evidence of a hot thermal excess
No full textSeveral persistent, low luminosity (LX ~ 1034 erg s-1), long spin period (P > 100 s) High Mass X-ray Binaries have been reported with blackbody components with temperatures > 1 keV. These hot thermal excesses have correspondingly small emitting regions (< 1 km2) and are attributed to the neutron star polar caps. We present a recent XMM-Newton target of opportunity observation of the newest member of this class, Swift J045106.8-694803. The period was determined to be 168.5 ± 0.2 s as of 17 July 2012 (MJD = 56125.0). At LX ~ 1036 erg s-1, Swift J045106.8-694803 is the brightest member of this new class, as well as the one with the shortest period. The spectral analysis reveals for the first time the presence of a blackbody with temperature kTBB = 1.8 +0.2-0.3 keV and radius RBB = 0.5 ± 0.2 km. The pulsed fraction decreases with increasing energy and the ratio between the hard (> 2 keV) and soft (< 2 keV) light curves is anticorrelated with the pulse profile. Simulations of the spectrum suggest that this is caused by the pulsations of the blackbody being ~ π out of phase with those of the power law component. Using a simple model for emission from hot spots on the neutron star surface, we fit the pulse profile of the blackbody component to obtain an indication of the geometry of the system
"Rhodium catalysed borylation reactions via direct and indirect c-h activation"
No full textThis thesis describes both direct and indirect C-H activation borylation processes, catalysed by several Rh-based catalyst precursors. Chapter One presents an overview of the processes investigated, namely diboration, dehydrogenative borylation, and direct C-H activation of hydrocarbon substrates, which give borylated species that are of interest to synthetic chemists. The uses of such borylated species are also highlighted. Chapter Two highlights the synthetic procedure for the synthesis of the catalyst precursor [Rh(acac)(C0E)(_2)], which can be used to prepare bis-phosphine catalyst precursors of the form [Rh(acacXP(_2))]- Although a procedure appears in the literature, it is not well cited. Also, this new procedure replaces [Tl(acac)] with [Na(acac)] and hence avoids the use of thallium salts. Chapter Three investigates the reaction of two vinyl(boronate) esters (VBEs) with Bzcat], and a wide array of catalyst precursors, which yield, among other species, the tris(boronate) esters ArCH(_2)C(Bcat)(_3) and ArCH(Bcat)CH(Bcat)(_3); the former results from the addition of both borons of the B(_2) unit to the same carbon atom, and are of interest due to their wide synthetic versatility. Chapter Four investigates the dehydrogenative borylation of alkenes using both HBpin and B2pin2, and several catalyst precursors. Most significantly, this route allows the synthesis of 1,1-disubstituted vinyl(boronate) esters that cannot be made by alkyne hydroboration. Chapter Five investigates the direct C-H activation of benzylic and aromatic hydrogens using the catalyst precursor [Rh(Cl)(N(_2))(P(^i)Pr(_3))(_2)]. This allows the functionalisation of hydrocarbon substrates, which are ubiquitous. Chapter Six investigates the stability of B-chlorocatecholborane to phosphines with the view to a boron analogue of the Heck reaction. In such a reaction, phosphmes would likely be employed on the catalyst. An understanding of the stability of the boron reagent under typical reaction conditions is needed, therefore, in order to prevent degradation of B-chlorocatecholborane, a process that is known for catecholborane
Role of Standard Magnetic Resonance Imaging
No full textBone disease is a clinical hallmark of multiple myeloma (MM), occurring in almost all patients during the course of the disease. It represents one of the main causes of morbidity and mortality in affected patients and can justify on its own the initiation of treatment in presence of a biopsy-proven medullary or extramedullary plasmacytoma. Over the past few years, modern imaging techniques have gained increasing importance in the management of MM. Currently, cross-sectional imaging is incorporated in the definition of myeloma-related bone disease deserving of treatment and is required for a correct staging as well as for treatment-response evaluation. Magnetic resonance imaging (MRI) allows to directly visualize bone marrow infiltration much earlier than myeloma-related bone destruction and it is considered the imaging gold-standard method for the detection of myeloma bone marrow involvement. MRI is the procedure of choice to evaluate painful lesions and discriminating between benign from malignant vertebral fractures and it has also the ability to localize spinal cord and/or nerve root compression for surgical intervention or radiation therapy. Moreover, whole-body MRI is currently included in the diagnostic work-up of otherwise considered asymptomatic myeloma and solitary bone plasmacytoma, with remarkable therapeutic implications. However, despite its added value in the initial disease assessment, conventional MRI is of limited value in the evaluation of response after treatment since it only provides morphological information. This chapter will give a comprehensive overview of the role of conventional MRI in diagnostic and post-treatment evaluation of patients with myeloma, underlining its strengths and weaknesses at various time points of the disease. Exhaustive acquisition protocols for an adequate evaluation of bone marrow disease involvement will be discussed in the light of currently accepted standards and the most important MR imaging findings will be illustrated alongside their prognostic value. Understanding the advantages and limitations of conventional MRI and its complementary value in staging and disease monitoring compared to other imaging techniques is essential to optimize patients’ management, especially in the new era of novel treatment approaches that have significantly improved rates and depth of response
Erratum to: Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus (Diabetic Medicine, (2006), 23, 9, (974-981), 10.1111/j.1464-5491.2006.01886.x)
No full textIn an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola.In an article by Marfella et al, the author name C. Saron is incorrect and should be listed as C. Sardu. Therefore the correct author list is: R. Marfella, F. Cacciapuoti, M. Siniscalchi, F. C. Sasso, F. Marchese, F. Cinone, E. Musacchio, M. A. Marfella, L. Ruggiero, G. Chiorazzo, D. Liberti, G. Chiorazzo, G. F. Nicoletti, C. Sardu, F. D'Andrea, C. Ammendola, M. Verza and L. Coppola
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