105 research outputs found
[The general intelligence factor: psychometric study. Approach to the problem of mental deterioration].
The authors have measured the correlation coefficient between W.B. and P.M. scores in 80 normal subjects, comparable for age and school. A mutual relationship between the two tests, connected by the hypothetical general intelligence factor "g", was really demonstrated. Correlation coefficient was positive and significative between W.B. total scores, excepted verbal scores, and P.M., the highest one between subtests 8, 9 and P.M. The intra-tests correlation between W.B. total scores and each subtest score was also evaluated: between sub-tests 8, 9 and W.B. total scores the highest one again. A new qualitative interpretation of mental deterioration in clinical neurology and psychiatry is suggested on the base of these results
The general rule applicable to torts, party autonomy and «specialized» conflict-of-law provisions in the Rome II Regulation
The paper discusses the main provisions of the European Union’s Regulation on tort conflicts (“Rome II”), by analyzing (i) the range of PIL techniques employed by the Regulation and (ii) its inspiring objectives. The need for legal certainty and foreseeability as to the law applicable permeates the whole Regulation and more specifically it motivates (a) the list of the issues which are governed by the lex delicti, as well as (b) the choice – within the general rule – of the connecting criterion based upon the locus damni. On the other hand, the will to «treat individual cases in an appropriate manner» has led to the introduction of exceptions to the general rule in relation to predetermined situations, such as the so called isolated torts, as well as to the provision of a more general and flexible power of the judge to determine the manifestly closer connection (through the escape clause). The establishment – as well as the preservation – of a reasonable balance among the parties has inspired not only the provision of special conflict-of-law rules (recital n. 19), but also the choice of the locus damni as the main connecting criterion (the fairness of such solution for the purposes of reaching a reasonable balance among the parties is extensively analysed in the paper), as well as the provision of peculiar limitations to the choice of the law applicable, in cases where weaker parties are involved. The safeguard of particular material interests deserving a special degree of protection is finally shown, for instance, by art. 7 concerning liability for environmental damage. In the light of the above, the paper underlines that the «system» of conflict-of-law rules laid down by Rome II Regulation appears to be particularly noteworthy in so far as it aims – by means of a remarkable range of solutions and techniques – at promoting several interests and objectives which are not always reciprocally consistent. Nonetheless, the real capacity of the Regulation to achieve such ambitious objectives will only be effectively assessable in the light of its future and broader application by the national courts. Paola Ivaldi is the author of paragraphs 3, 4, 5, 6 and 8
Civil Liability for Health Damages and Uniform Rules of Private International Law
The present contribution explores the attitude of uniform rules of private international law towards the achievement of the objective of health protection. As far as the rules on jurisdiction are concerned, the author – starting from an analysis of the international case-law involving health damages caused by multinational enterprises – focuses on the role that both the general forum provided by Article 4 of Regulation No 1215/2012 and the criterion of locus commissi delicti employed by Article 7(3) of the same Regulation might play for the purpose of health protection.
Attention is then turned to the conflict-of-law rules and more specifically to Article 5 of Regulation No 864/2007 and to the balance which such provision would be supposed to strike, according to Recital 20 of said Regulation, among different values including protection of consumers’ health. The article finally deals with the issue of recognition/exequatur of decisions concerning health damages and in particular of judgments awarding punitive damages, by critically assessing the Italian case-law on such issue, also in the light of the recent ruling of the Plenary Session of the Court of Cassation
Diritto dell'Unione europea e processo costituzionale (EU Law and the procedure before the Constitutional Court)
The paper illustrates the findings of the research financed under the Research Project of Relevant National Interest (PRIN) prot. n. 200832PPPJ, on the issue of “European integration through Procedural Law", which the author coordinated from 2012 as National and Local Unit Supervisor. In this perspective, the paper firstly underlines that the role of the Italian Constitutional Court has been increasingly restrained not only by EU rules having direct effects, but also by general principles to which the Court of Justice grants the same effects, as long as they justify «in any case» the disapplication of inconsistent national rules. Starting from this finding, the paper points out that the Constitutional Court gives nonetheless broad consideration to EU law issues and shows, in so doing, a remarkable opening towards «external» sources of law, as the constitutional judgment No. 80/2011 clearly confirms. In this view, the Court has recently suggested that the provisions of the EU Charter of Fundamental Rights could work as «special» parameters (“norme interposte”) for the purpose of constitutional review of legislation, in order to ensure an adequate level of protection to the rights thereby established. In the same view, the Court has also significantly rethought its relation with the European Court of Justice and it has referred to the ECJ both questions of interpretation and of validity of EU law, although so far only in the course of «principal» proceedings (i.e. proceedings started by the State or other «privileged» applicants) and not yet in the course of «incidental» proceedings (i.e. proceedings concerning questions raised by national courts), despite the unanimous opinion of legal scholarship. The Constitutional Court has finally asserted its capability to play a role within the European integration process by reserving its power (through the application of the so-called counter-limits theory) to review the Italian legislation implementing the European Treaties in the unlikely hypotheses of their contrast with the fundamental principles of the national constitutional order or with the fundamental rights of the individuals
Evaluation of antigen-specific T-cell responses with a miniaturized and automated method
Screening of Substrate Analogs as Potential Enzyme Inhibitors for the Arginine Kinase of Trypanosoma cruzi
Arginine kinase catalyzes the transphosphorylation between phosphoarginine and ADP. Phosphoarginine is involved in temporal ATP buffering and inorganic phosphate regulation. Trypanosoma cruzi arginine kinase phosphorylates only L‐arginine (specific activity 398.9 mUE‐min−1 mg−1), and is inhibited by the arginine analogs, agmatine, canavanine, nitroarginine, and homoarginine. Canavanine and homoarginine also produce a significant inhibition of the epimastigote culture growth (79.7% and 55.8%, respectively). Inhibition constants were calculated for canavanine and homoarginine (7.55 and 6.02 mM, respectively). In addition, two novel guanidino kinase activities were detected in the epimastigote soluble extract. The development of the arginine kinase inhibitors of T. cruzi could be an important feature because the phosphagens biosynthetic pathway in trypanosomatids is different from the one in their mammalian hosts.Fil: Pereira, Claudio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Alonso, Guillermo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Ivaldi, María Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Bouvier, León Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Torres, Hector Norberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Flawia, Mirtha Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentin
«La canzone d’autore»: dal concetto alla serie di studi
Definizione della 'canzone d'autore' come concetto e categoria estetica
Automatic Tuning and Selection of Whole-Body Controllers
Designing controllers for complex robots such as humanoids is not an easy task. Often, researchers hand-tune controllers, but this is a time-consuming approach that yields a single controller which cannot generalize well to varied tasks. This work presents a method which uses the NSGA-II multi-objective optimization algorithm with various training trajectories to output a diverse Pareto set of well-functioning controller weights and gains. The best of these are shown to also work well on the real Talos robot. The learned Pareto front is then used in a Bayesian optimization (BO) algorithm both as a search space and as a source of prior information in the initial mean estimate. This combined learning approach, leveraging the two optimization methods together, finds a suitable parameter set for a new trajectory within 20 trials and outperforms both BO in the continuous parameter search space and random search along the precomputed Pareto front. The few trials required for this formulation of BO suggest that it could feasibly be applied on the physical robot using a Pareto front generated in simulation.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Learning & Autonomous Contro
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