1,721,066 research outputs found
STD889265 Supplemental material - Supplemental material for Mosaic structure of the <i>penA</i> gene in the oropharynx of men who have sex with men negative for gonorrhoea
No full textSupplemental material, STD889265 Supplemental material for Mosaic structure of the penA gene in the oropharynx of men who have sex with men negative for gonorrhoea by Antonella Marangoni, Giacomo Marziali, Melissa Salvo, Antonietta D’Antuono, Valeria Gaspari, Claudio Foschi and Maria Carla Re in International Journal of STD & AIDS</p
From natural products based research, n ew substances for the treatment of Candida sp infections: the case of spirulina platensis
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Lactobacillus crispatus interferes with Chlamydia trachomatis infectivity through modulation of integrin exposure in cervical cells
No full textIn women, urogenital CT infections are often asymptomatic, thus remaining unnoticed and untreated. This can lead to complications and sequelae including pelvic inflammatory disease, tubal infertility and ectopic pregnancy (1, 2). A normal vaginal microbiota, dominated by lactobacilli, is crucial for the prevention of several urogenital and sexually transmitted infections, including Chlamydia (3, 4, 5). This aspect is strengthened by the demonstration that in case of bacterial vaginosis, a clinical condition characterized by the depletion of lactobacilli, a higher risk of STI transmission and acquisition is reported (6).
This study aimed to elucidate the molecular bases of the interaction among lactobacilli, Chlamydia trachomatis and epithelial cells. We evaluated the capacity of lactobacilli cells and supernatants to interfere with C. trachomatis infectivity in HeLa cells, by means of competition, exclusion and displacement mechanisms. Lactobacilli cells were the most active fraction, by means of an exclusion strategy. We investigated the potential mechanism of protection in Lactobacillus crispatus BC5 (model strain), and we demonstrated that the incubation of HeLa cell line with BC5 cells induces important modifications al the level of the epithelial plasma membrane, by altering lipid composition and α5 integrin subunit exposure. When α5 integrin subunits were masked by a specific blocking antibody, Chlamydia infection was precluded. α5 integrin subunit is thus crucial for the pathogen penetration into HeLa cells, and the anti-Chlamydia activity of BC5 can be directly linked to membrane properties modifications in epithelial cells. In conclusion, we identified a potential molecular mechanism at the basis of the protection exerted by Lactobacillus against the sexually transmitted pathogen Chlamydia trachomatis, getting insights into the role of the vaginal microbiota for the woman’s health
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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