239 research outputs found
Strategie e misure di tutela dei lavoratori nel contesto della sustainable corporate governance
No full text
Il controllo della prestazione di lavoro resa fuori dai confini dell’impresa
No full textThe author investigates the exercise of control prerogative beyond the company’s borders, while reflecting on the limitations imposed by the Workers' Statute to safeguard freedom and human dignity. By reiterating the prohibition of covert and impersonal monitoring, it is noted how the opportunities to verify the fulfillment of work performed outside the premises where surveillance personnel can be deployed are greatly limited. Nevertheless, attempts to expand them through interpretative means are deemed excessively risky in a context where the protection of human dignity and freedom is at stak
Optimization of washing conditions with biogenic mobilizing agents for marine fuel-contaminated beach sands
No full textWashing is a rapid and effective treatment to remediate contaminated sands impacted by oil spills, although synthetic additives used to increase extraction efficiency may cause additional pollution issues due to their intrinsic toxicity and very often low biodegradability. In this study, different biogenic mobilizing agents (soybean lecithins, cyclodextrins, cholic acids, plant-derived cleaners, rhamnolipids and sophorolipids) were tested in the washing of beach sands artificially contaminated with the Intermediate Fuel Oil IFO-180. Among these, a de-oiled soybean lecithin (SL-1), hydroxypropyl-beta-cyclodextrins (HPB-CD) and sophorolipids (SR) achieved hydrocarbon removals close to those attained with the synthetic surfactant Triton X-100 (TX) in preliminary washing tests carried out at constant mixing rate, water/sand ratio and IFO-180 contamination level using agents concentrations close to their critical micelle concentration (0.1% and 1% w/v for microbial and non-microbial agents, respectively). The effects of agent concentration, water/sand ratio, mixing rate and IFO-180 contamination on hydrocarbons removal were modelled using face-centred central composite design and ANOVA. Optimal washing parameters for sand contamination levels in the range 0.5-20 g/kg were identified with response surface methodology. While HPB-CD and SR performed equally to TX only at low sand contaminations, SL-1 attained hydrocarbon removal higher or equal to that of TX at any IFO-180 contamination and at lower application rates. SL-1 also outperformed TX when minimizing the water/sand ratio, i.e., the volume of water used. Considering its lower toxicity, higher biodegradability and higher hydrocarbon removal efficiencies, SL-1 is an effective and environmentally sustainable alternative to synthetic surfactants in washing treatments for marine fuel-contaminated sands
L’area dell’abitato compresa tra le Terme del Foro e le mura settentrionali
No full textThis paper gives a synthesis of the archaeological excavations held by the University of Napoli "L'Orientale" in the urban area between the "Terme del Foro" and the Northern wall
Intraoperative liver ultrasound still affects surgical strategy for patients with colorectal metastases in the modern era
No full textIntraoperative liver ultrasound still affects surgical strategy for patients with colorectal metastases in the modern era.
Ferrero A1, Langella S, Giuliante F, Viganò L, Vellone M, Zimmitti G, Ardito F, Nuzzo G, Capussotti L.
Author information1Department of Surgery, Ospedale Mauriziano "Umberto I", Largo Turati 62, 10128, Turin, Italy, [email protected].
Abstract
BACKGROUND: The present study was designed to evaluate the role of intraoperative ultrasound (IOUS) in intrahepatic staging and the impact on surgical strategy for patients with colorectal liver metastases (CRLM).
METHODS: The study included 515 patients who had undergone liver resection for CRLM at two tertiary care referral centers. Data from a prospectively collected database were retrospectively analysed. Early intrahepatic recurrence was assessed at 3 and 6 months after resection and was considered as residual disease undetected by IOUS. Performance of imaging modalities was compared by analysis of studies on individual patients.
RESULTS: A total of 1,370 liver metastases were detected preoperatively with a median of 3 imaging modalities. MRI and PET were performed in 51 and 42 % of the patients, respectively. Median number of days between last imaging and surgery was 18. Contrast-enhanced IOUS was performed in 136 patients (26.4 %). Intraoperatively, 293 new nodules were found in 132 patients: on histology 280 were CRLM (17.6 %). Surgical strategy was changed in 140 patients (27.2 %). On multivariate analysis synchronous and bilobar metastases ≥ 3 in number, BMI ≥ 30, and time between last imaging and surgery longer than 18 days resulted in predictive factors indicating new nodules detected by IOUS. Early intrahepatic recurrences were 3.7 and 7.9 % at 3 and 6 months. Performance of CT, MRI, FDG-PET, and intraoperative staging was compared: sensitivity was 63.6, 68.8, 53.6, and 92 % and specificity was 91, 92.3, 95.8, and 97.8 %, respectively
CONCLUSIONS: The use of IOUS continues to be mandatory for correct staging of patients with CRLM undergoing liver resection
Terminal oxazolinyloxiranes: synthesis, reaction with amines and regioselective beta-lithiation
No full textThe synthesis of terminal oxazolinyloxiranes, even in enantioenriched form, has been performed by
Darzens-type reaction of lithiated chloroalkyloxazolines with benzotriazolylmethanol (BtCH2OH) or by
chloromethylation of 2-acyl-2-oxazolines. The synthetic utility of such oxiranes based on their ability to
act either as electrophiles, undergoing ring-opening reactions with nucleophiles, or as nucleophiles in
form of the oxiranyl anions, generated by stereoselective beta-deprotonation, has been investigated
Un italiano al servizio del pasha d’Egitto. Alfonso Nuzzo Mauro e la narrazione della catastrofe di Missolungi
No full textIn the context of the rich literary production of Philhellenic inspiration, the siege of
Missolonghi had a wide impact such as few other episodes of the Greek Revolution.
The events of Missolonghi and the heroic resistance of its inhabitants aroused great
dismay in European public opinion and inspired a lot of literary works: short texts,
poems and dramas circulated in form of printed pamphlets or in periodicals, even
many years after the siege. The catastrophe of Missolonghi and The slave of the bazaar, by
Alfonso Nuzzo Mauro, published in Italy (1830) and France (1836), fits entirely into
this long and varied literary tradition. The author, who was the personal physician of
Ibrahim Pasha declares himself an eyewitness of the events and retraces the siege from
an unprecedented perspective: he combines the historical narration and the fictional
story of the characters, enriches the text with exotic and ethnographic details that run
through all the pages of his work
Le lesioni iatrogene della via biliare principale - Associata alla Relazione Biennale su invito al 104° Congresso della Società Italiana di Chirurgia, anno 2002 (Relatore: Gennaro Nuzzo)
No full textIl libro (monografia) descrive i molteplici aspetti connessi alle lesioni iatrogene della via biliare principale, in particolare a quelle che possono verificarsi in corso di colecistectomia: fattori predisponenti, prevenzione, diagnosi, trattamento. Il libro riporta inoltre i risultati di un'inchiesta nazionale sull'argomento, coordinata dal relatore e dai suoi collaboratori, a cui hanno partecipato 184 ospedali.The book (monograph) describes multiple issues related to iatrogenic biliary lesions, in particular to those occurring during cholecystectomy: predisposing factors, prevention, diagnosis, treatment. The book also reports the results of an Italian national survey on the topic, coodinated by the main author and by his collaborators, with the participation of 184 hospitals
ADViSELipidomics: a workflow for analyzing lipidomics data
No full textADViSELipidomics is a novel Shiny app for preprocessing, analyzing, and visualizing lipidomics data. It handles the outputs from LipidSearch and LIQUID for lipid identification and quantification and the data from the Metabolomics Workbench. ADViSELipidomics extracts information by parsing lipid species (using LIPID MAPS classification) and, together with information available on the samples, performs several exploratory and statistical analyses. When the experiment includes internal lipid standards, ADViSELipidomics can normalize the data matrix, providing normalized concentration values per lipids and samples. Moreover, it identifies differentially abundant lipids in simple and complex experimental designs, dealing with batch effect correction. Finally, ADViSELipidomics has a user-friendly Graphical User Interface (GUI) and supports an extensive series of interactive graphics
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