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“Scanning electron microscopy patterns in the antisperm antibodies detection with immunobead test”.
No full text“Post vasectomy antisperm immune reaction after testosterone-induced azoospermia”.
No full textWe describe preliminary experiments on the effects of testosterone-induced azoospermia on post-vasectomy antisperm antibody reaction in two subjects. Progressive resumption of spermatogenesis following gradual suspension of testosterone therapy was still associated with antisperm antibody formation. Post-vasectomy antisperm antibody production does not seem to be triggered exclusively by acute, sudden and massive reabsorption of spermatoza after vasectomy but also by slow, gradual and late sperm antigen reabsorption.
PIP: To learn more about the post-vasectomy autoimmune antisperm reaction, vasectomy was performed on 2 subjects who had achieved azoospermia through the administration of 250 mg/week of testosterone enanthate. Once the subjects had been azoospermic for 3 weeks and the vasectomy had been performed, testosterone administration was gradually reduced to allow spermatogenesis to resume. The tray agglutination test was used to detect sperm agglutinating antibodies. Antisperm antibody reaction was recorded in both subjects 3 months after vasectomy. The agglutination was head-to-head or mixed, not tail-to-tail. The antisperm antibody reaction was found only in blood in the 1st subject and in serum and seminal plasma in the 2nd subject. These findings appear to refute the authors' original hypothesis that it is the massive, sudden contact between antigens present on the spermatozoa and the immunocompetent cells that produces the post-vasectomy autoimmune reaction. Rather, it appears that the gradual and late reabsorption of sperm antigens resulting from the resumption of spermatogenesis after testosterone cessation acts as an antigenic stimulus in vasectomy patients. At present, the authors are investigating whether the immunological response is altered through the testosterone-induced block of spermatogenesis when testosterone treatment is continued for a longer period after vasectomy
Immunological usefulness of semen manipulation for artificial insemination homologous (AIH) in subjects with antisperm antibodies bound to sperm surface.
No full textThe authors report trials carried out in the preparation of semen for homologous artificial insemination in subjects with antisperm autoantibodies. The tests have demonstrated that swim-up is not able to select spermatozoa free of antibodies bound to the sperm surface. All the experiments of migration, dilution, antigenic competition and cryoconservation, carried out to evaluate the theoretical possibility of a better recovery of non "immunologically compromised" spermatozoa, have confirmed such negative results both with the Immunobead Test and Cytofluorimetric analysi
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Laser radiation and motility patterns of human sperm
No full textHuman sperm were exposed in vitro to laser radiation. An increase in progressive sperm motility was associated with a faster rate of sperm ATP consumption. Computer-assisted analysis of sperm motility confirmed the positive effect of laser irradiation on velocity and linearity of sper
“IBT diretto e tecniche indirette per lo studio della autoimmunità antispermatozoo: correlazioni ed aspetti sperimentali”.
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