6,656 research outputs found

    Michigan, Wisconsin and Minnesota 1836

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    Relief shown by hachures. "Engraved by Rawdon Clark & Co., Albany, N.Y." "Entered according to act of Congress... by J.H. Colton & Co. on the 9th Nov. 1835." Oriented with north toward the upper left. Prime meridians: Greenwich and Washington. Includes inset: Map of part of Ste. Marie River from actual survey. Indexed in:Karpinski 130E3 Moore 1-0809. This map has been conserved through the generosity of Dr. Donn K. Haglund, 2012.Color1:1,900,8

    Map of the United States and Texas, 1860

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    Map of the United States and Texas - Boundary Line and Adjacent Territory Determined and Surveyed in 1857, 8, 9, 1860. Inset: Points that can be easily found on the earth's surface. Clark, J.H., U.S. Commissioner, Department of the Interio

    Letter from J.H. Clark to Thomas Lamb Eliot

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    https://rdc.reed.edu/v1/resources/6ddaa9e5-84b4-4f0a-b381-d9bfc12d6a33/thumb/128.jp

    Letter from J.H. Clark to Thomas Lamb Eliot

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    https://rdc.reed.edu/v1/resources/ce816979-db6c-412a-9dce-a5f0a23adbc3/thumb/128.jp

    Letter from J.H. Clark to Thomas Lamb Eliot

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    https://rdc.reed.edu/v1/resources/8e931568-7009-404e-970d-d3e88d3df2c8/thumb/128.jpgThis is from the law office of S.M. Beckenridge

    J.H. Merryman et D.S. Clark, Comparative Law : Western European and Latin American Légal Systems. Cases and Materials

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    J.H. Merryman et D.S. Clark, Comparative Law : Western European and Latin American Légal Systems. Cases and Materials. In: Revue internationale de droit comparé. Vol. 31 N°2, Avril-juin 1979. pp. 475-477

    J.H. Merryman et D.S. Clark, Comparative Law : Western European and Latin American Légal Systems. Cases and Materials

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    J.H. Merryman et D.S. Clark, Comparative Law : Western European and Latin American Légal Systems. Cases and Materials. In: Revue internationale de droit comparé. Vol. 31 N°2, Avril-juin 1979. pp. 475-477

    Letters to Andrew Inglis Clark, Tasmania, from American colleagues and friends J.H. Allen and Mary W. Allen, 1891, 1897 and 1898

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    Letters to Andrew Inglis Clark, Tasmania, from American colleagues and friends J.H. Allen and Mary W. Allen, 1891, 1897 and 1898. C4/C9, C4/C10, C4/C11, C4/C1

    Clark, Margarete (Death, 1906-03-02)

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    Address: St. Marys Hospital- 749 W. 5th St.Age at death: 23-7-0328/Pg 34/1906/F W M/Cincinnati, Ohio/Dr. Louis A. Maloney/J.H. Finn/St. Joseph Cem.Original record filed in drawer labeled 'CLARK, N.-COHEN'

    A network meta-analysis to compare glycaemic control in patients with type 2 diabetes treated with exenatide once weekly or liraglutide once daily in comparison with insulin glargine, exenatide twice daily or placebo

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    AIMS: The glucagon-like peptide-1 receptor agonists (GLP-1 RAs) exenatide once weekly (ExQW) and liraglutide once daily (QD) are indicated to improve glycaemic control in patients with type 2 diabetes. Although glycaemic control with ExQW versus liraglutide QD 1.8 mg has been directly compared, no studies have compared ExQW with liraglutide QD 1.2 mg or determined the probable relative efficacies of various injectable therapies for glycaemic control; therefore, a network meta-analysis was performed to address these questions.METHODS: A systematic review identified randomized controlled trials of ≥24 weeks that compared ExQW, liraglutide QD (1.2 mg, 1.8 mg), insulin glargine, exenatide twice daily (ExBID), or placebo. Twenty-two studies evaluating 11 049 patients were included in the network meta-analysis. Mean differences in HbA1c relative to placebo or each other and probability rankings were estimated.RESULTS: Estimated mean differences in HbA1c versus placebo were -1.15% (95% CrI: -1.31 to -1.00) for ExQW, -1.01% (95% CrI: -1.18 to -0.85) for liraglutide 1.2 mg, and -1.18% (95% CrI: -1.32 to -1.04) for liraglutide 1.8 mg. HbA1c differences for ExQW versus liraglutide 1.2 mg and 1.8 mg were -0.14% (95% CrI: -0.34 to 0.06) and 0.03% (95% CrI: -0.14 to 0.18), respectively. The estimated mean difference in HbA1c between liraglutide 1.2 mg and 1.8 mg was 0.17% (95% CrI: 0.02-0.30). Results were consistent when adjusted for background antihyperglycaemic medications and diabetes duration.CONCLUSIONS: This network meta-analysis did not identify meaningful differences in HbA1c lowering between ExQW and both liraglutide doses, suggesting that these GLP-1 RAs have similar glycaemic effects.</p
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