1,720,965 research outputs found
Wandlungen des Mythos
No full textMit seinem Geschichtsromanzyklus "Amazonas", dessen Handlung eine Zeitspanne von rund Vierjahrhunderten umfasst – von den Ereignissen rund um die Eroberung Südamerikas im 16. Jahrhundert bis hin zu der Zeit des pränationalsozialistischen Deutschlands –, führt Alfred Döblin den Leser auf eine Reise durch die verschiedenen Phasen der Entwicklungsgeschichte der menschlichen Zivilisation. Claudia Cippitelli liest Döblins Geschichtsdarstellung als durchgehendes Wandeln des Mythischen und zeigt die Art und Weise, wie diese Evolution des Mythischen auf formaler Ebene realisiert wird. Durch die Untersuchung der textimmanenten Romanpoetik setzt sie sich zum Ziel, die Merkmale und Grundpfeiler der Geschichtsphilosophie festzulegen, die "Amazonas" implizit sind. Dabei steht im Mittelpunkt ihrer Arbeit die Auffassung, dass Döblin durch seine dichterische Darstellung der Weltgeschichte über den Anspruch der Zivilisation reflektiert, eine Wahrheit zu stiften und über die Gewalt, die auf derBasis dieses illusorischen Wahrheits- und Objektivitätsanspruches erzeugt wird
Tagungsbericht zur internationalen Tagung ‘Conceptions de l’Identité européenne / Konzepte europäischer Identität / Concezioni dell’identità europea II’, Venedig 28. bis 29. März 2022
No full textTagungsbericht zur internationalen Tagung ‘Conceptions de l’Identité européenne / Konzepte europäischer Identität / Concezioni dell’identità europea II’, Venedig 28. bis 29. März 202
Wandlungen des Mythos. Eine Untersuchung zur impliziten Geschichtsphilosophie der "Amazonas"-Trilogie Alfred Döblins
No full textNella tesi si indaga la filosofia della storia implicita in "Amazonas", trilogia storica di Alfred Döblin che narra prevalentemente gli eventi attorno la conquista europea del Sudamerica. Partendo dalla considerazione che nel romanzo i vari passaggi dell’evoluzione della civiltà vengono rappresentati come fenomeni di violenza, si sostiene la tesi che il romanzo contenga una riflessione di critica della civiltà (Zivilisationskritik) riguardante tutte le epoche e le culture rappresentate. Si propone una lettura secondo la quale nel romanzo la ragione viene ripetutamente svelata come mito, ovvero come narrazione che si convince di riuscire a interpretare la natura e, in questa autoillusione, produce violenza.
Tale interpretazione del romanzo viene sostenuta tramite il metodo del close reading effettuato su specifiche parti della trilogia. Il close reading permette di cogliere la corrispondenza che c’è fra contenuto e forma del romanzo: ai cambiamenti di visione del mondo che avvengono nel corso della storia umana – così come delineata nel romanzo – corrispondono variazioni stilistiche, con le quali Döblin riproduce l’evoluzione del narrare (quindi della trasmissione della storia) e svela il desiderio di dominio che si nasconde dietro la narrazione. Mettendo in luce la poetica implicita del romanzo (utilizzo delle fonti e delle tradizioni letterarie, elementi intertestuali, strutturali, linguistici, ecc.) si potrà, inoltre, confutare la diffusa opinione secondo la quale la critica döbliniana alla civiltà sarebbe rivolta esclusivamente al mondo europeo moderno.
Nell'analisi si fa riferimento alle teorie di filosofia politica, antropologiche e sociologiche dell'epoca di Döblin che hanno esercitato un'influenza sul suo pensiero o mostrano un'affinità con esso
Jenseits des Politischen: Alfred Döblins Reflexionen über Deutschland und Europa
No full textJenseits des Politischen: Alfred Döblins Reflexionen über Deutschland und Europ
Raman spectroscopy discriminates malignant follicular lymphoma from benign follicular hyperplasia and from tumour metastasis
No full textRaman spectroscopy is a non-destructive label-free technique providing biochemical tissue fingerprint. The objective of the present work was to test if Raman spectroscopy is a suitable tool to differentiate lymph nodes affected by different conditions, such as reactive follicular hyperplasia (benign), follicular lymphoma (low grade primary tumour), diffuse large B cell lymphoma (high grade primary tumour) and tumour metastasis (secondary tumours). Moreover, we tested its ability to discriminate follicular lymphomas by the tumour grade and the BCL2 protein expression. Lymph nodes collected from 20 patients, who underwent surgery for suspected malignancy, were investigated. Imaging of tissue areas from about 400 μm2 up to 2 mm2 was performed collecting Raman maps containing thousands of spectra. Partial least squares discriminant analysis (PLS-DA) - a bilinear classification method - was used to calculate lymph node classification models, in order to discriminate at first between benign and malignant tissues and successively among cancer types, grades and the BCL2 protein expression. This proof-of-concept study paves the way for the development of clinical optical biopsy tools for lymph node cancer diagnosis, complementary to histopathological assessment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Reduced lymphotoxin-beta production by tumour cells is associated with loss of follicular dendritic cell phenotype and diffuse growth in follicular lymphoma
No full textCytokine production is essential for follicular dendritic cell (FDC) maintenance and organization of germinal centres. In follicular lymphoma, FDCs are often disarrayed and may lack antigens indicative of terminal differentiation. We investigated the in situ distribution of cells producing lymphotoxin-beta (LTB), lymphotoxin-alpha (LTA), and tumour necrosis factor-alpha (TNFA) transcripts in human reactive lymph nodes and in follicular lymphomas with follicular or diffuse growth pattern. LTB was the cytokine most abundantly produced in germinal centres. LTB was present in nearly 90% of germinal centre cells whereas LTA and TNFA were detected in 30 and 50%, respectively. Moreover, the amount of LTB expressed in reactive germinal centre cells was 80-fold higher than that of LTA and 20-fold higher than that of TNFA. LTB-positive cells were more numerous in the germinal centre dark zone, whereas expression of the FDC proteins CD21, CD23, VCAM, and CXCL13 was more intense in the light zone. Tumour cells of follicular lymphomas produced less LTB than reactive germinal centre cells. The results of the in situ study were confirmed by RT-PCR; LTB was significantly more abundant in reactive lymph nodes than in follicular lymphoma, with the lowest values detected in predominantly diffuse follicular lymphoma. In neoplastic follicles, low production of LTB by tumour B cells was associated with weaker expression of CD21+/CD23+ by FDCs. Our findings detail for the first time the distribution of LTA-, LTB-, and TNFA-producing cells in human reactive germinal centres and in follicular lymphoma. They suggest the possibility that impaired tumour-cell LTB production may represent a determinant of FDC phenotype loss and for defective follicular organization in follicular lymphoma
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