5,134 research outputs found

    NAFLD: a multi-faceted morbid spectrum with uncertain diagnosis and complicated management

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    Non-alcoholic steatohepatitis (NASH) can be considered the pandemic of these times, because of its global diffusion alongside obesity, diabetes, and metabolic dysfunction. It is a disease that often poses many difficulties, since making an early diagnosis is often impossible since specific diagnostic tests and criteria are missing: so, it needs a high degree of suspicion. Most of the times the evolution to its more severe and terminal step, NASH cirrhosis, is unavoidable and so are the social pressure on health system and economic consequences it brings back. The aim of this article is to provide a review of the literature about both non-alcoholic fatty liver disease (NAFLD) and NASH, thus structuring a wide, comprehensive, 360-degree work with a focus on all major aspects of NAFLD, spanning from diagnosis, physiopathology and its repercussions on liver transplantation. Moreover, we also focus on patients related issues both in pre-and post-transplant management (when these patients are listed for liver transplant). NAFLD and NASH are a contemporary plague, and an exhaustive knowledge of the problem throughout all its aspects is necessary in order to lower economic weight that metabolic issues bring back and to have an open view to possible solutions to all management issues that NASH patients have and that are often prohibitive to a definitive cure (for example cardiovascular risk in patients otherwise eligible to liver transplantation). We aim to offer a complete view on the actual knowledge about NAFLD and NASH, by an extensive review of the literature. (Cite this article as: Di Renzo C, Vitale A, D'Amico F, Cillo U. NAFLD: a multi-faceted morbid spectrum with uncertain diagnosis and complicated management. Minerva Surg 2021;76:450-66. DOI: 10.23736/S2724-5691.21.08729-0

    Quando le immagini diventano un serbatoio di dati per le aziende

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    Sempre più spesso i consumatori utilizzano le immagini postate sui social media – Instagram in particolare – per comunicare, esprimere e condividere i propri sentimenti, le proprie emozioni e impressioni. Di conseguenza, le aziende si stanno attivando per utilizzare questo imponente patrimonio per comprendere in maniera più approfondita i comportamenti e le preferenze degli individui al fine di orientare le proprie decisioni di marketing, di innovazione e comunicazione. • Una recente ricerca ha raccolto 50.000 immagini Instagram, e i metadata associati, postate tra il 2015 e il 2018 a Los Angeles, San Francisco, Boston, New York, Paris, Londra e dove comparivano diversi loghi incluso quello di Under Armour. Questo ha permesso di selezionare le immagini con il logo del brand; definire i cluster di hashtag all’interno di queste immagini; identificare i vari segmenti di consumatori e le modalità di appropriazione del marchio e di utilizzo dello stesso. • Tale processo attiva un potenziale enorme per i brand in termini di personalizzazione dell’offerta e dell’attività di engagement delle differenti comunità. Questo avviene in base alle specifiche dinamiche di interazione e di costruzione di significato che si creano tra utente e brand

    Francesco Scorza Barcellona o della passione agiografica

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    L'autrice traccia, sul filo dei ricordi, il profilo scientifico ed umano di Francesco Scorza Barcellona ed introduce gli studi raccolti nel volume.The author traces, on the thread of memories, the scientific and human profile of Francesco Scorza Barcelona and introduces the studies collected in the book

    Extraordinary disease-free survival in a rare malignant extrarenal rhabdoid tumor: A case report and review of the literature

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    Background: Malignant extrarenal rhabdoid tumor of the gastrointestinal tract is rarely reported in the literature. It is characterized by poor prognosis and aggressive metastatic features. A literature review evidenced only 19 cases, with poor outcome. Case presentation: We report a case of a colonic "pure" malignant extrarenal rhabdoid tumor with metastatic nodes in a 65-year-old Caucasian man. He was treated surgically with no recurrence, no adjuvant chemotherapy, and with 4-year survival without disease at the time of the submission of this article. Conclusions: We present an extraordinary case of long-term survival due to the extended surgical treatment. We believe that the absence of organ metastasis at presentation is a positive prognostic factor, although pathology confirmed node involvement (13/38 positive) on microscopy. © 2018 The Author(s)

    Delle lodi di don Francesco Medici de' principi di Toscana : orazione /

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    Engraved t.p. vignette of Medici arms. On recto of 2nd leaf is Callot's full-page engraved port. of Francesco de' Medici, son of Grand Duke Ferdinand I. It is in Lieure's 1st state. The port. also appeared the same year in Alessandro Adimari's Esequie dell' ill.mo & ecc.mo principe don Francesco Medici (Florence : Gio. Donato & Bernardino Giunti); see Lieure. Large woodcut Giunti device on p. [31].Lieure, J. Jacques Callot,Mode of access: Internet.At head of front pastedown is bookplate of Francesco Riccardi de Vernaccia (Florence, ca. 1780; see Gelli, p. 387). Below it is the label of Horatius (Orazio) Landau, with stamped shelfmark 53021. At foot is the bookplate of U. Manganelli, signed with the initials SER. A dedicatory inscription at foot of t.p. has been scratched out.Binding: modern marbled paper, backed in green vellum. Date, author & title writte on spine.Port. trimmed into the image at right margin and foot
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