1,720,958 research outputs found
Improving patient safety after rigid bronchoscopy in adults: laryngeal mask airway versus face mask a pilot study
No full textBackground: There are still no clear guidelines in the literature on per procedural bronchoscopic management for anesthesiologists, and few relevant datasets are available. To obtain rapid recovery from anesthesia, it is often necessary to keep patients in the recovery room for several hours until they become clinically stable. In this study, we tested the hypothesis that the laryngeal mask airway (LMA) enables better respiratory and hemodynamic recovery than the oxygen face mask (FM) in patients undergoing rigid bronchoscopy. Methods: Twenty-one patients undergoing elective bronchoscopy of the upper airway were randomized to ventilation assistance with FM or LMA after a rigid bronchoscopy procedure under general anesthesia. The primary endpoint was duration of post-surgical recovery and the secondary endpoints were postoperative hemodynamic and respiratory parameters. Assessment of the study endpoints was performed by an intensive care specialist blinded to the method of ventilation used. The statistical analysis was performed using the Fisher’s Exact test for nominal data and the Student’s t-test for continuous data. Results: There was no statistically significant difference in post-procedural time between the two groups (P=0.972). The recovery parameters were significantly better in the LMA group than in the FM group, with significantly fewer desaturation, hypotensive, and bradycardic events (P <0.05). Conclusion: We conclude that the LMA may be safer and more comfortable than the FM in patients undergoing rigid bronchoscopy
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Smoking pattern in men and women: A possible contributor to sex differences in smoke-related lung diseases
Get PDFhoc test odds would be 0.076 [0.25 3 0.303] and corresponding to a post
hoc test probability of 7.6% [0.076/(1 1 0.076)]) (8).
We designed the classifier to assess organ quality for donor pool
expansion strategies, to identify organs for possible rehabilitation on ex vivo
lung perfusion, and to identify potential targets for directed therapies in
clinical trials. The validation of the pathways identified in this transcript
panel highlights the importance of the innate immune system in the
development of PGD and identifies its constituent genes as potential
therapeutic targets. This work builds on previous work identifying
associated pathways and developing clinical predictors important in PGD
to assess risk prior to procurement to facilitate decision making for
potential therapeutics and advanced surgical therapies (3, 4, 7).
Although these results are promising, there are limitations to
consider. The cohort sample size was small, therefore reducing overall
power. Nonetheless, this study represents a temporal validation in tissue
of prior findings in blood and BAL using a conventional machine
learning approach. Tissue biopsy is an invasive procedure with associated
risks. We validated our classifier in tissue to ensure that all lung
compartments were sampled (endothelial, epithelial, and lymphoid), and
we acknowledge that further refinement will be necessary to scale to
clinical practice. Additionally, translating gene expression prediction to
the bedside will require development of point-of-care technologies using
abbreviated gene sets, such as those using microfluidics (9). As this study
cohort did not overlap with our prior cohorts, we were unable to assess
interactions between blood, BAL, and tissue compartments. Although
this work is supported by several other studies that show association (3,
4, 10), additional validation will be necessary to confirm discriminant
and diagnostic validity and generalizability.
In summary, we have demonstrated that transcript analysis of
donor lung tissue, using an innate immunity pathway classifier, can be
used in conjunction with clinical variables to predict PGD with
excellent discrimination and precision. With the ability to identify
organ risk, this panel has the potential to alter future PGD clinical trial
designs and lead to the development of precision medical approaches.
As PGD drives morbidity and mortality associated with lung transplant, further research in this area has the potential to improve
outcomes following transplantation
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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