1,354,172 research outputs found
Intravitreal bevacizumab for macular complications from retinal arterial macroaneurysms : reply
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Imagining and creating solidarity futures: from the CERS experience to the regeneration of public housing heritage in Naples Immaginare e realizzare futuri solidali: dall’esperienza della CERS alla rigenerazione del patrimonio di edilizia pubblica a Napoli
No full textThe growing importance of energy independence and security has been amplified by rising prices due to ongoing conflicts and the need for decarbonization. Renewable Energy Communities (RECs) have been introduced at the European level as autonomous entities aimed at facilitating the integration of renewable sources and promoting local energy production. Despite the residential sector offering significant potential, legal and administrative challenges, as well as decisions regarding the placement of these communities, continue to hinder their widespread adoption, particularly in Italy’s inner and southern regions. This study focuses on highlighting the potential economic, environmental, and social benefits associated with the establishment of an REC in a residential area of inner Abruzzo. Specifically, the analysis covers Campli, a municipality in the province of Teramo. The municipality is characterized by a complex territorial structure (with 42 localities), it is partly within the Gran Sasso and Monti della Laga National Park, it included in the 2016 earthquake zone and classified within Italy’s inner areas (SNAI). In this study, the proposed REC model envisions energy sharing from renewable energy systems installed on existing rooftops, with direct involvement of local citizens and public administration
Vizio o virtù?
No full textI vizi capitali hanno sempre costituito un importante tema di riflessione. Fin da Aristotele, che li definisce «gli abiti del male», si è intuito che i vizi, mettendo a nudo la fragilità e la miseria umana, sono una via privilegiata per conoscere il fondo oscuro e misterioso dell’anima. Questo è il motivo per il quale anche oggi i vizi capitali sono oggetto di un rinnovato interesse, non solo da parte della teologia, ma anche della psicologia del profondo, della filosofia e della letteratura
Combined reduced fluence photodynamic therapy and intravitreal ranibizumab for polypoidal choroidal vasculopathy
No full textPurpose: We performed a prospective noncomparative study to report the results of
reduced fluence photodynamic therapy (PDT) combined with intravitreal ranibizumab in
patients with polypoidal choroidal vasculopathy with active exudation and hemorrhage.
Methods: Seventeen polypoidal choroidal vasculopathy eyes were treated, and followup
for all patients was 12 months. Photodynamic therapy was administered with reduced
fluence (exposure time of 70’’) and followed (48 hours later) by intravitreal ranibizumab (0.5
mg in 50 mL). Intravitreal ranibizumab, with or without reduced fluence PDT, was repeated
as indicated by clinical and angiographic findings.
Results: During the follow-up, the mean best-corrected visual acuity significantly
improved from 0.45 ± 0.29 logarithm of the minimum angle of resolution at baseline to
0.29 ± 0.28 logarithm of the minimum angle of resolution at 12 months. The mean total
macular volume (documented by optical coherence tomography retinal map examination)
decreased from 7.5 ± 1.18 mm3 to 6.7 ± 0.8 mm3. In 95% of the cases, best-corrected
visual acuity remained stable or improved.
Conclusion: Reduced fluence PDT limits laser exposure, minimizing the risks of PDTinduced
adverse effects. Intravitreal injections of ranibizumab 0.5 mg reduced bleeding and
leakage in polypoidal choroidal vasculopathy eyes and interfere with rebound upregulation
of vascular endothelial growth factor because of PDT-induced choroidal hypoperfusion.
Combined treatment may improve treatment outcomes in polypoidal choroidal vasculopathy
while minimizing ocular and systemic complications of treatment
Neovascular Glaucoma Induced by Peripheral Retinal Ischemia in Neurofibromatosis Type 1: Management and Imaging Features
No full textPurpose: To report the case of a young patient affected by neurofibromatosis 1 (NF-1) with peripheral retinal ischemia-induced neovascular glaucoma and the peculiar spectral-domain optical coherence tomography (SD-OCT) features. Material and Methods: A 13-year-old boy affected by NF-1, as diagnosed according to established criteria, was referred with a diagnosis of hypertensive uveitis in his left eye. He underwent a complete ophthalmic examination and comprehensive blood work with viral and immunological tests. The case was documented with fluorescein angiography (FA) and SD-OCT. When the intraocular pressure (IOP) of the left eye decreased and the cornea cleared, FA revealed retinal ischemia and leakage from pathologic retinal vessels. SD-OCT revealed foveal hypoplasia secondary to the complete absence of the retinal nerve fiber layer. Results: Peripheral retinal ischemia-induced neovascular glaucoma was diagnosed. The patient underwent Ahmed valve implantation to control his IOP, and subsequent retinal photocoagulation by argon laser and intravitreal bevacizumab injection were performed to control neovascularization. Discussion: Retinal ischemia in NF-1 might lead to neovascular glaucoma: lowering of the IOP with surgical implantation of an Ahmed valve, regression of neovascularization by argon laser panretinal photocoagulation and intravitreal injection of bevacizumab can be a helpful way to control such a complication
Effects of a low-phosphorus, low- protein diet supplemented with essential amino acids and ketoanalogues on serum beta-endorphin in chronic renal failure.
No full textThe effects of a vegetarian low-protein, low-phosphorus diet supplemented with essential amino acids and ketoanalogues, on the serum beta-endorphin, growth hormone, parathyroid hormone, thyroid hormones (T3 and T4), pituitary TSH and total cortisol were studied in 12 male chronic uremics. beta-Endorphin decreased, as well as growth hormone. Parathyroid hormone and T3 improved significantly, reaching almost normal values. It is hypothesized that the correction of the beta-endorphin excess may account in part for the improvement of some endocrinological and metabolic effects exerted by this dietary treatment. The possible pathophysiological mechanisms which could explain the antiendorphinic action of this treatment in uremic patients are discussed, as well as the possible beneficial endocrine and metabolic effects exerted by the fall in circulating beta-endorphin
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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