1,720,979 research outputs found
Working procedures of an hot line insulators washing device operating at reduced distance from surface insulators
No full textDevelopment and validation of a high-fidelity neonatal pneumothorax simulator
No full textNeonatal pneumothorax is a clinical emergency procedure that -if not solved within minutes -can lead to major clinical complications, including death. For this reason, advanced management skills are required. High-fidelity simulation represents a valuable training tool for residents that allows to gain experience and confidence thus preserving patient safety. Nevertheless, systems now available on the market and literature prototypes provide poor anatomical and physiological features, thus limiting the realism of the simulation and the training. With the aim to overcome these limitations and allow the training of all aspects of the clinical procedure, an innovative highfidelity neonatal pneumothorax simulator was realized by exploiting two airtight pressurized chambers coupled together with self-sealing needle insertion areas. The simulator assessment phase was carried out involving both expert neonatologists and residents. Before and after the clinical procedure, surveys were used for collecting subjective evaluations. Finally, procedural time was recorded. Based on the obtained results, neonatologists considered the simulator a valid teaching and retraining tool. Moreover, thanks to a simple setting and the possibility to provide real-time feedback, the simulator proved to be a valid tool for training also in critical conditions of personal distancing, e.g., Covid-19 pandemic, which often requires remote operation
Valutazione funzionale ed ecografica della tiroide nel deficit staturale da ritardo intrauterino di crescita
No full textEarly-onset sepsis risk calculator: a review of its effectiveness and comparative study with our evidence-based local guidelines
Full text linkBackground: According to most early-onset sepsis (EOS) management guidelines, approximately 10% of the total
neonatal population are exposed to antibiotics in the first postnatal days with subsequent increase of neonatal and
pediatric comorbidities. A review of literature demonstrates the effectiveness of EOS calculator in reducing
antibiotic overtreatment and NICU admission among neonates ≥34 weeks’ gestational age (GA); however, some
missed cases of culture-positive EOS have also been described.
Methods: Single-center retrospective study from 1st January 2018 to 31st December 2018 conducted in the
Division of Neonatology at Santa Chiara Hospital (Pisa, Italy). Neonates ≥34 weeks’ GA with birth weight ≤ 1500 g,
34–36 weeks’ GA neonates with suspected intraamniotic infection and neonates ≥34 weeks’ GA with three clinical
signs of EOS or two signs and one risk factor for EOS receive empirical antibiotics. Neonates ≥34 weeks’ GA with
risk factors for EOS or with one clinical indicator of EOS undergo serial measurements of C-reactive protein and
procalcitonin in the first 48–72 h of life; they receive empirical antibiotics in case of abnormalities at blood exams
with one or more clinical signs of EOS. Two hundred sixty-five patients at risk for EOS met inclusion criteria; they
were divided into 3 study groups: 34–36 weeks’ GA newborns (n = 95, group A), ≥ 37 weeks’ GA newborns (n =
170, group B), and ≥ 34 weeks’ GA newborns (n = 265, group A + B). For each group, we compared the number of
patients for which antibiotics would have been needed, based on EOS calculator, and the number of the same
patients we treated with antibiotics during the study period. Comparisons between the groups were performed
using McNemar’s test and statistical significance was set at p < 0.05; post-hoc power analysis was carried out to
evaluate the sample sizes.
Results: 32/265 (12.1%) neonates ≥34 weeks’ GA received antibiotics within the first 12 h of life. According to EOS
calculator 55/265 (20.7%) patients would have received antibiotics with EOS incidence 2/1000 live births (p < 0.0001).
Conclusion: Our evidence-based protocol entails a further decrease of antibiotic overtreatment compared to EOS
calculator. No negative consequences for patients were observed
Endocrine Diseases of Newborn
No full textCongenital hypopituitarism results from a deficiency of any or all of the hormones secreted by the anterior pituitary gland or by the posterior pituitary gland. It is uncommon. The annual incidence ranges from 1 to 42 new cases per million and a prevalence of 300-455 cases per million. Reduced cortisol and/or aldosterone production may be the consequence of primary cortical adrenal deficiency or damage. Isolated cortisol insufficiency may also be a consequence of pituitary/hypothalamic ACTH/CRF deficiency.
The definition of the lower normal limit of blood glucose is controversial. A common definition of hypoglycaemia is a plasma glucose level < 35 mg/dL in term or < 40 mg/dl in premature infants, although some studies have suggested 47-55 mg/dl.
The definition of the upper normal limit of blood glucose in the newborn remains uncertain. A blood glucose level higher than 125 mg/dl or plasma glucose level > 150 mg/dl, regardless gestational age or postnatal age, are usually considered abnormal
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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