1,722,120 research outputs found

    Orchestration of Stepwise Synaptic Growth by K+ and Ca2+ Channels in Drosophila

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    Synapse formation is tightly associated with neuronal excitability. We found striking synaptic overgrowth caused by Drosophila K+-channel mutations of the seizure and slowpoke genes, encoding Erg and Ca2+-activated large-conductance (BK) channels, respectively. These mutants display two distinct patterns of “satellite” budding from larval motor terminus synaptic boutons. Double-mutant analysis indicates that BK and Erg K+ channels interact with separate sets of synaptic proteins to affect distinct growth steps. Post-synaptic L-type Ca2+ channels, Dmca1D, and PSD-95-like scaffold protein, Discs large, are required for satellite budding induced by slowpoke and seizure mutations. Pre-synaptic cacophony Ca2+ channels and the NCAM-like adhesion molecule, Fasciclin II, take part in a maturation step that is partially arrested by seizure mutations. Importantly, slowpoke and seizure satellites were both suppressed by rutabaga mutations that disrupt Ca2+/CaM-dependent adenylyl cyclase, demonstrating a convergence of K+ channels of different functional categories in regulation of excitability-dependent Ca2+ influx for triggering cAMP-mediated growth plasticity.National Institutes of Health (U.S.) (Grant NS 26528

    Morphological and phylogenetic evidence reveal Tetraploa cylindrica sp. nov. (Tetraplosphaeriaceae, Pleosporales) from Saccharum arundinaceum (Poaceae) in Yunnan Province, China

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    Liao, Chun-Fang, Dong, Wei, Thilini Chethana, K. W., Pem, Dhandevi, Phookamsak, Rungtiwa, Suwannarach, Nakarin, Doilom, Mingkwan (2022): Morphological and phylogenetic evidence reveal Tetraploa cylindrica sp. nov. (Tetraplosphaeriaceae, Pleosporales) from Saccharum arundinaceum (Poaceae) in Yunnan Province, China. Phytotaxa 554 (2): 189-200, DOI: 10.11646/phytotaxa.554.2.7, URL: http://dx.doi.org/10.11646/phytotaxa.554.2.

    Confirmatory Factor Analysis of the Short Dispositional Flow Scale–2 and Short Flow State Scale–2 for Persons With Schizophrenia in Taiwan

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    Abstract Date Presented 3/30/2017 The Chinese versions of the Short Dispositional Flow Scale–2 (DFS–2) and Short Flow State Scale–2 (FSS–2) showed goodness of fit when administered to persons with schizophrenia in Taiwan, and future studies would be suggested to apply the same validation method for the Short DFS–2 and Short FSS–2 in other cultures or populations. Primary Author and Speaker: Lin-Jye Huang Additional Authors and Speakers: Fu-Chang Hu, Chinyu Wu, Yi-Hong Yang, Shu-Chun Lee, Yung-Chun Fang, Hsu-Chang Huang, Kuan-Yu Lai, Chun-Yi Yu</jats:p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Erratum to "A Tale of Two Setae: How Morphology and ITS2 Help Delimit a Cryptic Species Complex in Eulophidae (Hymenoptera: Chalcidoidea)"

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    Li, Jian-An, Shi, Ming-Peng, Cong, Lin, Gu, Ming-Yu, Chen, Yi-Heng, Wang, Si-Yi, Li, Zhen-Hua, Zan, Chun-Fang, Wei, Wan-Fu (2019): Erratum to "A Tale of Two Setae: How Morphology and ITS2 Help Delimit a Cryptic Species Complex in Eulophidae (Hymenoptera: Chalcidoidea)". Insect Systematics and Diversity (AIFB) 3 (5), No. 10: 1-1, DOI: 10.1093/isd/ixz021, URL: http://dx.doi.org/10.4103/1673-5374.35350

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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