1,523 research outputs found

    Response to the Round Table on Why Did We Choose to Industrialize? Montreal 1819–1849

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    Author Robert C.H. Sweeny responds to comments on his award-winning book, Why Did We Choose to Industrialize? Montreal 1819–1849.L’auteur Robert C.H. Sweeny répond aux commentaires de son livre récompensé, Why Did We Choose to Industrialize? Montreal 1819–1849

    Sensitization of Hep3B hepatoma Cells to Cisplatin and Doxorubicin by Corilagin.

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    The anticancer action of gallotannins is a well-developed topic. We have demonstrated the in vivo antitumour activity of corilagin on Hep3B hepatoma using the xenograft athymic nude mice model. Here, we further report the potential sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilagin. Our results showed that corilagin is able to enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B hepatoma cells. We speculate the possible use of corilagin in combination with low dosages of the anticancer chemotherapeutic standard drugs like cisplatin and doxorubicin, with the aim of obtaining an increment in the anticancer effect. Copyright © 2013 John Wiley & Sons, Ltd

    Recourse against Judgments in the Netherlands

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    In the 1980s, the Netherlands witnessed the start of a comprehensive programme of reform in the fields of judicial organisation and procedure. The reform programme consists of three stages, of which the first has now been completed. This has, amongst other things, resulted in the consolidation of several administrative procedures which were formerly adjudicated by different judicial bodies, in the Arrondissementsrechtbank. Consequently, the Arrondissementsrechtbank has obtained extensive administrative jurisdiction together with its jurisdiction in civil and criminal cases. As part of the reforms in the second stage, a bill has been submitted to Parliament which contains changes in the court structure. It is proposed to abolish the Kantongerecht and to reallocate its jurisdiction to the Arrondissementsrechtbank, transforming the latter court into a general first-instance court. In addition, the bill contains changes in the Code of Civil Procedure. In the present report the author discusses the current situation January 1998

    Interpolation with reflection invariant positive definite functions.

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    Concepts of abstract harmonic analysis can be used to provide a unifying framework for basis function methods, like radial basis functions in Euclidean spaces or zonal basis functions on the sphere. To illustrate how these concepts can be applied reflection invariant functions are considered. A specialization of the Bochner-Godement Theorem leads to a characterization of suitable basis functions

    Bifurcation Routes in Financial Markets

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    The heterogeneity of expectations among traders introduces an important non-linearity into the financial markets. In a series of papers, Brock and Hommes, propose to model economic and financial markets as adaptive belief systems. Asset price fluctuations in adaptive belief systems are characterized by phases of close-to-the-fundamental-price fluctuations, phases of optimism where most agents follow an upward price trend, and phases of pessimism with small or large market crashes. In this paper will be discussed the EMH benchmark and forecasting rules of fundamentals and trend extrapolators. Some illustrative examples are supplied.heterogeneity of expectations, adaptive belief systems, forecasting rules, fundamentals, trend extrapolators equations, limit cycles, asymptotical stability

    John Ploughman's Talk or Plain Advice for Plain People.

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    I admit that I have read only two pages of this book (154-5). It seems a non-stop barrage of one-liners. The author does indeed, as the cover illustration suggests, take the bull by the horns! I picked the book up because its frontispiece of Aesop's fox and crow depicts the book's insight: The fox admires the cheese, not the raven (154). My two pages had lots of good zingers in them, like He who believes in promises made at elections has long ears, and may try to eat thistles. I suspect there are many more fable-related proverbs along the way in the book, but for now I will let someone else find them. This printing represents the 544th thousand.This is a hardbound book (hard cover)C.H. Spurgeo

    Microencapsulation-protected l-ascorbic acid for the application of human epithelial HaCaT cell proliferation.

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    Abstract l-ascorbic acid is an abundant water-soluble nutrient found in vegetables and fruits. It enhances the cell proliferation, which is helpful in wound healing process. However, it is relatively unstable and easily degraded under external environments including acidity, alkalinity, evaporation, heat, oxidization, light or moisture. Its storage remains challenged. This study reported the development of l-ascorbic acid microcapsules using the natural protein, gelatin, and the natural polysaccharide, agar, as the wall protection carrier. The physical properties including entrapment efficiency, particle size, surface morphology, chemical compositions and release profile were identified. The cell proliferation of l-ascorbic acid microcapsules was stronger than the free drug. Significant cell growth in microencapsulated l-ascorbic acid-treated human epithelial HaCaT cells was observed when compared with untreated control. Since cell proliferation and wound repair are closely related, it is believed that l-ascorbic acid microcapsules would effectively increase the potential effect of wound healing activity in human skin

    Commentary

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