2,958 research outputs found
aE Journal 2015/2016: aE/INTECTURE innovating architecture
No full textThe graduation studio of Architectural Engineering focuses on the integration of (new) technology in architecture. For this purpose, the name aE/ INTECTURE® was devised, which will be developed further as a brand in the coming years. Students start with a technical fascination and translate this into an architectural concept, finally being able to implement this within the environment in a responsible way. ‘If technology is the answer, what is the question?‘ Under the guidance of a team of enthusiastic (guest) lecturers, students search for the dot on the horizon that is necessary for coming up with solutions that improve the quality of the built environment and make it more sustainable. In addition, either the ‘making‘ (make) or ‘the energy and material flow’ (flow) is used and applied as a basis in different contexts.Architectural Engineerin
aE Journal 2017/2018: aE/Intecture innovating architecture
No full textDriven by the need to think differently about resources, energy, power generation, the choice of materials, and user involvement, we see the built environment in a new perspective. The program, Architectural Engineering, seeks for innovative and inspiring architectural solutions for social and environmental issues throughout all scales.To achieve this, innovation of the architectural challenge is high on our agenda. Innovation is more than just a technical improvement. How do you implement new current issues in modern architecture? We anticipate new energy, materials, and circularity. We also use the current environment of the metropolis and the countryside. We add new buildings, strengthen existing stock, and work on new components of buildings. From high to low tech. From digital to traditional, looking carefully to the context.Architectural Engineerin
Main motifs in the prose of the leftist author Kang Kyŏng-ae
No full textThe subject of this bachelor thesis is the life and work of the Korean writer Kang Kyǒng-ae, with a focus on her short prose. The aim of this thesis is an analysis of two works - Salt and Darkness - with attention to the context of the author's time. Nowadays, Kang Kyǒng-ae is considered a significant author of the 1930s and her works reflect the phenomenon of Korean emigrants in Manchuria. For a long time, leftist tendencies caused her prose to be neglected, which resulted in a considerably limited number of studies concerned with her work, in comparison to the number of studies about other writers. There are virtually no Czech studies of her work. The text of the thesis initially presents the timeframe of Kang's authorship and then analyzes select works of hers. The analysis of the works focuses on recurring motifs, which are put into a historical and social context. Keywords Kang Kyǒng-ae, Korean 1930s literature, leftist literature, Sogǔm, Ǒdu
Kabuki syndrome: international consensus diagnostic criteria
No full textBackground Kabuki syndrome (KS) is a clinically recognisable syndrome in which 70% of patients have a pathogenic variant in KMT2D or KDM6A. Understanding the function of these genes opens the door to targeted therapies. The purpose of this report is to propose diagnostic criteria for KS, particularly when molecular genetic testing is equivocal. Methods A n international group of experts created consensus diagnostic criteria for KS. Systematic PubMed searches returned 70 peer-reviewed publications in which at least one individual with molecularly confirmed KS was reported. The clinical features of individuals with known mutations were reviewed. Results T he authors propose that a definitive diagnosis can be made in an individual of any age with a history of infantile hypotonia, developmental delay and/ or intellectual disability, and one or both of the following major criteria: (1) a pathogenic or likely pathogenic variant in KMT2D or KDM6A; and (2) typical dysmorphic features (defined below) at some point of life. Typical dysmorphic features include long palpebral fissures with eversion of the lateral third of the lower eyelid and two or more of the following: (1) arched and broad eyebrows with the lateral third displaying notching or sparseness; (2) short columella with depressed nasal tip; (3) large, prominent or cupped ears; and (4) persistent fingertip pads. Further criteria for a probable and possible diagnosis, including a table of suggestive clinical features, are presented. Conclusion A s targeted therapies for KS are being developed, it is important to be able to make the correct diagnosis, either with or without molecular genetic confirmation
Biographical Romance, or The Wonders of ihe Life of An Émigrée of Choice: Fryderyk Járosy (1889–1960) – the Author of Unwritten Memoirs of Life Among the Polish Diaspora in London
No full textEnglish version. Original issue: “Archiwum Emigracji” 2009, no. 1 (10)https://apcz.umk.pl/AE/article/view/AE.2009.01
Genetic landmarks through philately: Woodrow Wilson ‘Woody’ Guthrie and Huntington disease
No full textAutour du Nepos d'Alburnus, Maior, Panes, fils de Bizo (AE, 20081167=AE, 2007, 1201) : petit-fils ou neveu
No full textInternational audienceIn this article, the author studies again the inscription on a stone of a nepos from Alburnus Maior: Panes, son of Bizo (AE, 2008, 1167 = AE,2007, 1201). If the word nepos very often means « grandson », there are cases where it means « nephew ». The author pays special attention to the Latin kinship terminology in this inscription because names and lines are not Roman but peregrine. So, there is ambiguity as we cannot exactly know the relations between all these names. Now, between a grandfather and his grandson or an uncle and his nephew, there is the same number of generations. It is necessary for one to compare these to other inscriptions and words in addition to nepos (auia, auus, nurus, gener, pater, mater) or only with nepos in Rhenodanubian provinces (Raetia, Pannoniae, Moesiae, Dacia): these 67 inscriptions are in an appendix.The author concludes that the these two possibilities exist here
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