2,956 research outputs found
RIC-HSCT for MF/SS
Advanced-stage mycosis fungoides and Sezary syndrome (MF/SS) have a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT), particularly using a reduced-intensity conditioning (RIC) regimen, is a promising treatment for advanced-stage MF/SS. We performed RIC-HSCT in nine patients with advanced MF/SS. With a median follow-up period of 954days after HSCT, the estimated 3-year overall survival was 85.7% (95% confidence interval, 33.4-97.9%) with no non-relapse mortality. Five patients relapsed after RIC-HSCT; however, in four patients whose relapse was detected only from the skin, persistent complete response was achieved in one patient, and the disease was manageable in other three patients by the tapering of immunosuppressants and donor lymphocyte infusion, suggesting that graft-versus-lymphoma effect and "down-staging" effect from advanced stage to early stage by HSCT improve the prognosis of advanced-stage MF/SS. These results suggest that RIC-HSCT is an effective treatment for advanced MF/SS
Factors associated with low bone mass in hemodialysis patients: A cross-sectional correlation study
A critical examination of hypernova remnant candidates in M101. I. MF 83
[[abstract]]The supernova remnant (SNR) candidate MF 83 in M101 is coincident with a very luminous X-ray source. Based on the high X-ray luminosity, it has been suggested that MF 83 is a "hypernova remnant" requiring an explosion energy about 2 orders of magnitude higher than normal supernovae. We have analyzed high-quality ground-based and Hubble Space Telescope observations of MF 83, and find that MF 83 is a star formation region, consisting of a large ionized gas shell and four H II regions along its periphery. Continuum images show OB associations in these H II regions and within the large shell. The shell has an expansion velocity of similar to 50 km s(-1) and a diameter of similar to 270 pc. The optical properties of this shell in MF 83 are similar to those of X-ray-bright superbubbles in the Large Magellanic Cloud. If the X-ray emission is indeed diffuse, the implied thermal energy in MF 83 is high, a few times 10(52) ergs. This amount of thermal energy requires a large number of concentrated supernova explosions or one powerful explosion. Future X-ray observations with a high angular resolution are needed to resolve the diffuse emission and point sources in MF 83, in order to determine more accurately the thermal energy in the shell interior and its required explosion energy.[[fileno]]2010506010001[[department]]天文
Preparation of mono-sized epoxy/MF microcapsulesin the appearance of polyvinyl alcohol as co-emulsifier
For epoxy microcapsules embedded in concrete as mechanic-triggered self-healing adhesive, globular shape with uniform size is the basic requirement to ensure the solid shell broken and the liquid core released at a designed stress. In this paper, monodispersed melamine\u96formaldehyde (MF) resin-walled epoxy E-51 microcapsules were successfully fabricated in an in situ polycondensation process, in which a certain amount of polyvinyl alcohol (PVA) solution was added as coemulsifier to control the microcapsules\u92 shape and size. Detail investigation shows, with the cooperation of PVA, the microcapsule morphologies and size distribution were ease to be adjusted by the parameters such as emulsifying agents, agitation rate, pH value and acidification time
ACT Family Violence Intervention Program review
This paper reports on a review of the Australian Capital Territory’s Family Violence Intervention Program, which provides an interagency response to family violence matters.
The scope of the review was to analyse the program’s activities and outcomes using 2007–08 data provided by participating agencies, supported by in-depth interviews with key stakeholders including victims whose matters had been finalised in court. After the completion of this report, additional data from 2008–09 and 2009–10 was made available by some Family Violence Intervention Program (FVIP) participating agencies. Although not within the scope of this evaluation, these data pointed to some preliminary improvements in the FVIP
A Nonlinear Analysis on the Euro Exchange Rate Using MF-DFA
The objective of this study is to examine the nonlinear characteristics of the Euro exchange rate. Many nonlinear approaches have been applied in the finance field. Multifractal detrended fluctuation analysis (MF-DFA) is one of the popular methodologies employed to detect the nonlinear properties of a time series. The MF-DFA analysis is executed by removing the trend of a time series and abstracting its multifractality. This paper examines the features of the entire Euro exchange rate series and the sub-periods during the Global Financial Crisis and European Sovereign Debt Crisis. The overall pattern of the Euro exchange rate is determined. Further, the degrees of complexity during the two crisis periods are detected.1. Introduction / 2. Multifractal Detrended Fluctuation Analysis / 3. A brief review of the Euro exchange rate / 4. Empirical analysis / 5. Conclusion / 6. Future researc
NF membrane fouling by aluminum and iron coagulant residuals after coagulation-MF pretreatment
The effects of coagulant residuals on fouling of a nanofiltration (NF) membrane were investigated. Experiments were carried out with a laboratory-scale microfiltration (MF)-NF setup and a pilot MF-NF plant. In the laboratory-scale experiments, NF feed water was pretreated with poly-aluminum chloride (PACl) or alum followed by MF. NF membrane permeability declined when the feed water contained residual aluminum at 18 μg/L or more, but not when it was lower than 9 μg/L. When pretreated with ferric chloride, no substantial decline of NF membrane permeability was observed: residual iron did not affect the permeability. When SiO2 was added to the water before the pretreatment with PACl, the NF membrane permeability declined at about double the speed. Thermodynamic calculations and elemental analysis of foulants recovered from the membranes indicated that the majority of inorganic foulants were compounds composed of aluminum, silicate, and possibly potassium. In the pilot plant, NF feed was pretreated by PACl. Transmembrane pressure for NF doubled over 4.5 months of operation. Although the aluminum concentration in the NF feed was not high (30 μg/L), analysis of membrane foulants revealed excessive accumulation of aluminum and silicate, also suggesting that aluminum residuals caused the membrane fouling by alumino-silicates or aluminum hydroxide
Zircon and whole-rock Hf isotope constraints on the petrogenesis of Transhimalayan plutonic rocks
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